Citations 1
Size-dependent alterations in phrenic motor neuron perineuronal nets following cervical spinal hemisection
Cheung, Sang Won , Fogarty, Matthew J. , Zhan, Wen-Zhi, Bellingham, Mark C. , Noakes, Peter G. , Sieck, Gary C. , Bellingham, Mark C , Sieck, Gary , Fogarty, Matthew J , Zhan, Wen‐Zhi
Journal of Neurophysiology | June 8, 2026 | Volume: 136 | Issue: 1 | Pages: 180-190
Neuroplastic changes in phrenic motor neurons that underlie recovery from spinal cord injury may be mediated by perineuronal nets. We show that changes in perineuronal nets around phrenic motor neurons occur within 7 days after cervical spinal cord injury, and that the increase in perineuronal nets around larger phrenic motor neurons was more pronounced. These changes are consistent with substantial reorganization of the neural network onto intact phrenic motor neurons following cervical spinal cord injury.