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Roy, Opalina

Mayo Clinic

Manipal Academy of Higher Education

Citations 1

Functional Changes in the Fallopian Tube: Environmental Factors, Lifestyle, Pathological Conditions and Pharmacological Agents
Roy, Opalina, Kumari, Sandhya, Adiga, Satish Kumar , Kumar, Anujith , Venkatraman, Ganesh, Kalthur, Guruprasad , Venkatraman, Ganesh , Kannan, Nagarajan , Adiga, Satish Kumar , Joshi, Manjunath Bandu , Kannan, Nagarajan

Cells | February 2, 2026 | Volume: 15 | Issue: 3 | Pages: 269

10.3390/cells15030269 Get It

The fallopian tubes are critical segments of the female reproductive tract and are essential for transporting gametes and embryos. It creates a conducive environment necessary for successful fertilization, early embryo development, and embryo transport. The cellular composition and function of the fallopian tube are tightly regulated by the sex hormones estradiol and progesterone. Therefore, any pathological/ metabolic condition or exposure to exogenous agents with the potential to alter endocrine levels can have a significant impact on fallopian tube function and health. This review summarizes the effects of medications, infections, pathological conditions, lifestyle choices, and environmental factors that can significantly impact the morphology, histology, cellularity, and functionality of the fallopian tube.