Citations 1
(389) Multicenter Evaluation on the Use of Down-Sized Cylinders Penile Prosthesis: When to Go Narrow?
Lee, J, Swerdloff, Daniel , Sadeghi‐Nejad, Hossein , Pearce, Ian , Lentz, A, Gross, Kelli, Hotaling, James M. , Sempels, Maxime, Park, S Hun, Renterghem, Katrien Van, Hatzichristodoulou, G, Levy, Jason A. , Andrianne, Robert, Hsieh, Tung‐Chin , Modgil, Vaibhav , Jones, Adam , Warner, J, Ziegelmann, M., Suarez-Sarmiento, A, Perito, P, Simhan, Jay , Gross, M, Yafi, Faysal A. , Barham, David , Lee, J, Chawareb, Elia Abou , Hammad, M, Miller, Jake A. , Azad, Babak Kazemzadeh , Osmonov, D, Burnett, Arthur L. “Bud” , Lentz, A, Hatzichristodoulou, Georgios , Levy, J, Jones, James M. , Suarez‐Sarmiento, Alfredo, Gross, Martin
The Journal of Sexual Medicine | December 9, 2025 | Volume: 22 | Issue: Supplement_4 | Pages: No page available
Abstract Introduction Down-sized inflatable penile prosthesis (IPP) cylinders are useful in cases with substantial penile fibrosis such as history of priapism or prior infection. Although down-sized IPP cylinders have a clear role in fibrotic corpora, their role in primary implant cases is unclear. Objective To identify factors associated with the use of down-sized cylinders in men undergoing primary IPP placement. Methods We conducted a retrospective analysis of 4,389 patients undergoing primary IPP placement from our multicenter database. Patients were categorized by down-sized (AMS 700 CXR, Coloplast NB) vs. standard sized cylinders (AMS 700 CX, AMS 700 LGX, Coloplast Titan). We collected demographic, intraoperative, and postoperative data. A multivariable analysis was performed to identify factors associated with use of down-sized cylinders Results A total of 4,389 men undergoing primary inflatable penile prosthesis (IPP) placement were included in the study, with a mean age of 62.3 ± 10.3 years. Among them, 1,485 (34%) had diabetes and 2,131 (49%) had hypertension. A total of 406 down-sized cylinders and 3,983 standard cylinders were implanted. Non-infectious complications occurred more frequently with the use of down-sized cylinders (odds ratio [OR] = 2.0, p < 0.001). Specifically, non-infectious complications were reported in 44 out of 185 men (23.8%) with down-sized cylinders, compared to 192 out of 2,727 men (10.9%) with standard cylinders. Cylinder complications constituted 13.9% and 13.0% of the non-infectious complications in the down-sized and standard cylinder groups, respectively. Conclusions The rate of cylinder-related complications were similar between the down-sized cylinder and standard cylinder groups. Urologists should be prepared to place down-sized cylinders during IPP placement in diabetic men and in men requiring serial dilation due to fibrosis. Disclosure Any of the authors act as a consultant, employee or shareholder of an industry for: Intuitive Surgical, Fidelis, Urofill, Boston Scientific, Coloplast, Cynosure, Antares Pharma, Clarus Pharmaceuticals, Acerus Pharma; Endo Pharma.