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Ashkar, Motaz

https://orcid.org/0000-0002-3132-5153

Mayo Clinic

Mayo Clinic

Citations 1

Successful Use of Glucagon-Like Peptide-1 Receptor Agonist in a Patient With Recurrent Hypertriglyceridemia-Induced Pancreatitis
Guralwar, Chinmay , Mitsuhashi, Shuji , Ashkar, Motaz , Chedid, Victor G , Chedid, Victor

ACG Case Reports Journal | November 17, 2025 | Volume: 12 | Issue: 11 | Pages: No page available

10.14309/crj.0000000000001890 Get It

ABSTRACT Glucagon-like peptide-1 receptor agonists (GLP-1RA) are generally avoided in patients with a history of pancreatitis due to concerns about potential associated risk of acute pancreatitis (AP). However, their role in managing severe hypertriglyceridemia (HTG) remains underexplored. We present a case of a 42-year-old woman with recurrent HTG-induced AP who was initiated on GLP-1RA and achieved 15% weight loss, sustained triglyceride reduction, and remained AP-free while on that therapy. This case highlights a potential new role for the use of GLP-1RAs for HTG-AP.