Citations 1
Fluorescence based live cell imaging identifies exon 14 skipped hepatocyte growth factor receptor (MET) degraders
Yang, Lin , Lin, Wan-Hsin, Feathers, Ryan W. , Ayers-Ringler, Jennifer , Tolosa, Ezequiel J. , Kizhake, Amritha G., Kizhake, Smitha , Kubica, Sydney P., Boghean, Lidia , Naldrett, Michael J. , Rana, Sandeep , Schaefer-Klein, Janet, Roden, Anja C. , Kosari, Farhad , Anastasiadis, Panos Z. , Feathers, Ryan, Tolosa, Ezequiel, Roden, Anja, Natarajan, Amarnath , Mallareddy, Jayapal Reddy , Lin, WanâHsin , Alvarez, Sophie , Singh, Sarbjit , Zahid, Muhammad , Borad, Mitesh J. , Natarajan, Amarnath , Mansfield, Aaron S.
RSC Advances | April 4, 2025 | Volume: 15 | Issue: 13 | Pages: 10419-10425
Despite ongoing efforts to employ structure-based methods to discover targeted protein degraders (TPD), the prevailing strategy remains synthesizing a focused set of heterobifunctional compounds and screening them for target protein degradation.