Dominguez, Alejandro Nieto

INTRODUCTION: This study investigates seasonal variations in eosinophilic esophagitis (EoE)-related emergency department visits among adults. METHODS: We analyzed the National Emergency Department Sample (2016–2021), identifying adult patients with EoE using ICD-10 codes. Generalized additive models assessed seasonal patterns. RESULTS: Among 18,791 EoE-related emergency department visits, a significant seasonal variation was observed, peaking in summer and nadiring in winter. This pattern was consistent across all US regions. CONCLUSION: Seasonal dietary habits and social behaviors likely contribute to EoE exacerbations. Healthcare providers should emphasize management strategies during high-risk periods, particularly summer months and weekends.

AbstractBackground and AimEsophageal cancer significantly contributes to US cancer mortality, with notable racial disparities. This study aims to provide updated esophageal cancer mortality trends among Black and White adults from 1999 to 2020.MethodsCDC‐WONDER was used to identify Black and White adults in the United States from 1999 to 2020. We calculated age‐standardized mortality rates, absolute rate differences, and rate ratios to compare the mortality differences between these populations.ResultsFrom 1999 to 2020 in the United States, there were 303 267 esophageal cancer deaths, with significant racial disparities. The age‐adjusted mortality rate for Black adults fell from 6.52 to 2.62 per 100 000, while for White adults, it declined from 4.19 to 3.97 per 100 000, narrowing the racial mortality gap. Gender‐wise, the study showed a decrease in the mortality rate from 3.31 to 2.29 per 100 000 in Black women, but an increase from 1.52 to 1.99 per 100 000 in White women. Among young men, the rate dropped in Black men from 12.82 to 6.26 per 100 000 but rose in White men from 9.90 to 10.57 per 100 000. Regionally, Black adults in the Midwest and South initially had higher mortality rates than Whites, but this gap reduced over time. By 2020, Black men had lower mortality rates across all regions.ConclusionsOver the last two decades, age‐adjusted esophageal cancer mortality decreased in Black adults but stabilized in White adults, reflecting distinct cancer trends and risk factors. The study highlights the importance of tailored public health strategies for healthcare access and risk factor management.