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Salassa, John R.

Mayo Clinic

Mayo Clinic

Citations 15

Malignant Pyoderma
Salassa, John R., Winkelmann, R.K., McDonald, Thomas J.

Otolaryngology–Head and Neck Surgery | January 5, 2017 | Volume: 89 | Issue: 6 | Pages: 917-922

10.1177/019459988108900608 Get It

Malignant pyoderma is a rare inflammatory pyoderma of unknown cause with characteristic destructive and necrotizing ulcers limited to the face, neck, and upper trunk. The typical lesions are small, purulent, periauricular ulcers. Enlargement and coalescence result in extensive lesions that may ultimately destroy portions of the external ear. The histopathologic findings are acute and chronic inflammation with necrosis. Treatment consists of long‐term systemic corticosteroids. We present two new cases and alert otolaryngologists to the seriousness of this disease.
‘Colonic Type’ Adenocarcinoma of the Nasal Cavity and Paranasal Sinuses
Salassa, John R., McDonald, Thomas J. , Weiland, Louis H.

Otolaryngology–Head and Neck Surgery | April 8, 2016 | Volume: 88 | Issue: 2 | Pages: 133-135

10.1177/019459988008800205 Get It

Primary “colonic type” tumors of the nasal cavity and paranasal sinuses are adenocarcinomas with histologic features similar to those of colonic cancers. Their behavior is one of local invasion and recurrence. Unlike tumors of the colon, they rarely metastasize. Surgical resection by means of lateral rhinotomy with or without radiation is the treatment of choice. Prognosis is poor. This type of tumor should be recognized by pathologists and its implications should be known to head and neck surgeons.
Recurrent Adult Myofibromatosis: A Case Report
Hogan, Stephen F., Salassa, John R.

American Journal of Clinical Pathology | March 17, 2016 | Volume: 97 | Issue: 6 | Pages: 810-814

10.1093/ajcp/97.6.810 Get It

Posterior Wall Pharyngectomy with Preservation of Laryngeal Function
Levine, Paul A., Salassa, John R., Lynch, Dennis J., Lenis, Armando, Verheyden, Charles N.

Otolaryngology–Head and Neck Surgery | November 25, 2015 | Volume: 97 | Issue: 1 | Pages: 79-82

10.1177/019459988709700116 Get It

Dual-Acquisition Extracranial Computed Tomographic Angiography-Enhanced Neck Computed Tomography before Transoral Laser Microsurgery in Head and Neck Cancer Patients
Weindling, Steven M. , Salassa, John R., Casler, J.D., Chellini, David

The Neuroradiology Journal | April 22, 2015 | Volume: 24 | Issue: 3 | Pages: 379-391

10.1177/197140091102400306 Get It

Transoral laser microsurgery (TLM) is an alternative surgical technique for piecemeal endoscopic resection of mucosal-based aerodigestive tract tumors. Though uncommon, potentially catastrophic postoperative bleeding may occur with this technique secondary to vascular injury along invasive tumor inner margins. We describe our preliminary results using a preoperative dual-acquisition extracranial computed tomographic angiography (CTA)-enhanced neck computed tomographic (CT) imaging and postprocessing protocol developed to improve visualization of mucosal-based head and neck tumors and adjacent arterial branches with the objective of facilitating TLM surgery and reducing secondary bleeding complications. Twenty patients with known head and neck cancers anticipated for TLM resection were selected for a dual-acquisition CTA-CT scanning and postprocessing protocol. The mucosal-based pharyngeal tumors and peritumoral vessel enhancement were compared on matched CTA and enhanced neck CT axial images. Operative reports and clinical notes were retrospectively reviewed to identify patients in whom the TLM surgical approach was altered or changed to conventional open surgery as a result of presurgical CTA-CT findings. Enhancement of peritumoral vasculature was almost uniformly superior (19 of 20 patients) on extracranial CTA compared with enhanced neck CT images. In six candidates for TLM surgery (30%), CTA findings resulted in a change in surgical approach to improve intraoperative peritumoral vascular control. In this small pilot series, primary tumor-peritumoral vessel relationships delineated by the addition of extracranial CTA to preoperative enhanced neck CT frequently impacted the surgical approach and facilitated TLM planning.
Intraventricular Tension Pneumocephalus as a Complication of Paranasal Sinus Surgery
Davis, D.H., Laws, Edward R. , McDonald, Thomas J. , Salassa, John R., Phillips, Lawrence H.

Neurosurgery | May 30, 2010 | Volume: 8 | Issue: 5 | Pages: 574-576

10.1227/00006123-198105000-00011 Get It

Abstract A case of intraventricular tension pneumocephalus occurring as a complication of paranasal sinus surgery is presented. The pathophysiology of tension pneumocephalus is discussed and emphasis is placed on the potentially life-threatening increase in intracranial pressure that occurs. Tension pneumocephalus requires prompt diagnosis and treatment.
Manofluorographic and functional outcomes after endoscopic laser cricopharyngeal myotomy for cricopharyngeal bar
Özgürsoy, Ozan Bağış , Salassa, John R.

Otolaryngology–Head and Neck Surgery | April 22, 2010 | Volume: 142 | Issue: 5 | Pages: 735-740

10.1016/j.otohns.2009.08.020 Get It

ObjectiveTo investigate the manofluorographic and functional outcomes after endoscopic laser cricopharyngeal myotomy (ELCPM) for cricopharyngeal (CP) bar.Study DesignCase series with chart review.SettingAcademic medical center.Subjects and MethodsReview of patients undergoing ELCPM between 2001 and 2007 was undertaken to determine the demographic, clinical, and manofluorographic findings before and six months after surgery. Two groups were established according to pharyngeal driving pressures: normal pressure group (> 55 mm Hg) and low pressure group (< 55 mm Hg).ResultsFourteen patients underwent ELCPM for CP bar without a concomitant head and neck or Zenker's procedure. There were no major surgical complications. All 14 patients improved at least one stage on the Functional Outcome Swallowing Scale (FOSS) after surgery. There was a statistically significant decrease in the FOSS stages after surgery. Videofluoroscopy demonstrated a significant postoperative increase in the mean cross‐sectional CP opening (CP‐area) from 32.75 to 123.52 mm2. Manofluorographic pressure recordings showed a significant postoperative decrease in the intrabolus pressure gradient across the cricopharyngeal region (IB‐Gra) from 25.44 to 13.22 mm Hg. Despite significant overall results, the change in the IB‐Gra showed no difference between the patient groups.ConclusionSubjective (FOSS) and objective manofluorographic (CP‐area, IB‐Gra) improvement in CP bar patients occurred after ELCPM. We suggest IB‐Gra as a reliable objective indicator for patients who might benefit from ELCPM and as an appropriate parameter for follow‐up after surgery. However, continued research on a larger patient population is required to enhance our understanding of CP bar and predictors of outcome after treatment of CP bar dysphagia.
Computed tomographic angiography with three‐dimensional reconstruction for transoral laser microsurgery
Salassa, John R., Özgürsoy, Ozan Bağış , Weindling, Steven M. , Casler, John D.

Otolaryngology–Head and Neck Surgery | February 19, 2010 | Volume: 142 | Issue: 3 | Pages: 351-354

10.1016/j.otohns.2009.11.028 Get It

ObjectiveTo identify major arteries in relationship to large pharyngeal tumors during transoral laser microsurgery.Study DesignCase series with planned data collection.SettingMayo Clinic, Jacksonville, Florida.Subjects and MethodsWe developed a new technique that combines three‐dimensional CT angiography and enhanced soft‐tissue neck CT for evaluation of pharyngeal tumors before transoral laser microsurgery. Data from CT angiography were used to create three‐dimensional images of the tumor and adjacent arterial branches to better orient the surgeon to the spatial relationships of major arteries and pharyngeal tumors. Included were selected patients who had large tumors involving the pharynx and who underwent transoral laser microsurgery.ResultsEighteen patients were studied from June 2008 through January 2009. Tumor enhancement was absent or modest in four of 18 patients. Three of these four patients had superficial squamous cell carcinomas and one had adenoid cystic carcinoma. The remaining 14 patients had good tumor enhancement. The tumor involved the lingual artery in three and displaced the lingual or facial artery in two of these 14 patients. One anomalous right inferior thyroid artery was identified. Compared with routine enhanced soft‐tissue neck CT, three‐dimensional CT angiography greatly enhanced the anatomical relationships of the major arteries. In one patient, the surgeon's approach was changed after three‐dimensional CT angiography demonstrated an encased lingual artery.ConclusionThree‐dimensional CT angiography was useful in identifying the anatomical orientation of major arteries and the planning of transoral laser microsurgery to treat tumors involving the pharynx.
Love and Fear of Heights: The Pathophysiology and Psychology of Height Imbalance
Salassa, John R., Zapala, David A.

Wilderness & Environmental Medicine | December 28, 2009 | Volume: 20 | Issue: 4 | Pages: 378-382

10.1580/1080-6032-020.004.0378 Get It

Individual psychological responses to heights vary on a continuum from acrophobia to height intolerance, height tolerance, and height enjoyment. This paper reviews the English literature and summarizes the physiologic and psychological factors that generate different responses to heights while standing still in a static or motionless environment. Perceptual cues to height arise from vision. Normal postural sway of 2 cm for peripheral objects within 3 m increases as eye-object distance increases. Postural sway >10 cm can result in a fall. A minimum of 20 minutes of peripheral retinal arc is required to detect motion. Trigonometry dictates that a 20-minute peripheral retinal arch can no longer be achieved in a standing position at an eye-object distance of >20 m. At this distance, visual cues conflict with somatosensory and vestibular inputs, resulting in variable degrees of imbalance. Co-occurring deficits in the visual, vestibular, and somatosensory systems can significantly increase height imbalance. An individual's psychological makeup, influenced by learned and genetic factors, can influence reactions to height imbalance. Enhancing peripheral vision and vestibular, proprioceptive, and haptic functions may improve height imbalance. Psychotherapy may improve the troubling subjective sensations to heights.
Postoperative bleeding in transoral laser microsurgery for upper aerodigestive tract tumors
Salassa, John R., Hinni, Michael L., Grant, David G., Hayden, Richard E.

Otolaryngology–Head and Neck Surgery | August 23, 2008 | Volume: 139 | Issue: 3 | Pages: 453-459

10.1016/j.otohns.2008.06.010 Get It

ObjectivesTo report the incidence, cause, and outcome of bleeding after transoral laser microsurgery.Study DesignA two‐center prospective case series analysis.Subjects and MethodsSeven hundred one patients underwent transoral laser microsurgery for tumors of the oral cavity, pharynx, and larynx from June 1996 through September 2006.ResultsTen patients (1.4%) experienced postoperative bleeding between 0 and 17 days after surgery. Five patients had previously untreated tumors, and five patients had salvage surgery. Two patients (0.3%) had minor bleeding and required observation only. Five patients (0.7%) experienced major bleeding requiring exploration under general anesthesia. Three patients (0.4%) had catastrophic life‐threatening bleeds, two of whom died. The bleeding vessel was identified as the lingual artery in four patients, the superior laryngeal artery in two, the facial artery in two, and unknown in two.ConclusionsBleeding after transoral laser microsurgery is rare but potentially life‐threatening.