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Melville, David M.

https://orcid.org/0009-0001-6942-6216

Mayo Clinic

Mayo Clinic in Arizona

Citations 5

Intravascular Lipoma
Brown, Parker J. , Melville, David M. , Wyse, Aaron , Melville, David

Seminars in Musculoskeletal Radiology | December 3, 2025 | Volume: 29 | Issue: 06 | Pages: 959-962

10.1055/s-0045-1810112 Get It

Intravascular lipomas are rare benign tumors composed of adipose tissue that originate from the walls of blood vessels. They most commonly arise from veins, are typically asymptomatic, and rarely occur in the lower extremities. When large, these tumors can cause symptoms related to venous obstruction, such as swelling and pain. We report a case of a 75-year-old man with an intravascular lipoma in the right common femoral vein, identified during evaluation of lower extremity swelling and poorly healing ulcers. Surgical resection was ultimately required. This case contributes to the few published reports of pathologically proven symptomatic intravascular lipomas involving the lower extremity veins. Comprehensive preoperative imaging played a critical role in characterizing the lesion. The case facilitates a discussion of key differential diagnoses, such as atypical lipomatous tumors/well-differentiated liposarcoma and leiomyosarcoma.
Response to: An International ASXL3 Natural History Study: Deep Phenotypic Analyses Including Detailed Reports of a Milder Phenotype, Novel Associations,
Hasan, Shemonti , Melville, David M. , Chaaban, Mohammad Karam, Harahsheh, Ehab , Olarewaju, Bukola A., Baudhuin, Linnea M. , Shamoun, Fadi , Osundiji, Mayowa A. , Melville, David, Chaaban, Mohammad K, Osundiji, Mayowa Azeez , Shen, Wei

American Journal of Medical Genetics Part A | September 29, 2025 | Volume: 200 | Issue: 2 | Pages: 559-561

10.1002/ajmg.a.64272 Get It

A Multimodality Review of Thumb Metacarpophalangeal Joint Injuries
Haug, Logan P. , Long, Jeremiah R. , Noland, Shelley S. , Melville, David M. , Flug, Jonathan A.

Roentgen Ray Review | May 22, 2025 | Volume: 1 | Issue: 2 | Pages: No page available

10.2214/r3j.24.01031 Get It

Peripheral Spondyloarthritis: Conceptualization and Diagnosis as a Distinct Rheumatologic Subset of Disease
Chroneos, Paul, Melville, David M. , Long, Jeremiah R. , Flug, Jonathan A. , Melville, David, Flug, Jonathan A , Nagaraja, Vivek

Seminars in Musculoskeletal Radiology | March 31, 2025 | Volume: 29 | Issue: 02 | Pages: 236-248

10.1055/s-0045-1802350 Get It

AbstractPeripheral spondyloarthritis (pSpA) encompasses multiple entities affecting the musculoskeletal system with classic findings of synovitis, enthesitis, and tenosynovitis. It remains poorly defined when compared with the axial spondyloarthritides due to nonspecific symptoms, ill-defined imaging findings, and lack of specific testable biomarkers. Previous research has tried to distinguish between the two disease entities using clinical presentations, scoring systems, and radiographic findings; however, overlap remains. We summarize the current classification of pSpA, imaging findings, and the distinction between these entities and axial spondyloarthritis.
Comparison of Ultrasound and MRI with Intraoperative Findings in the Diagnosis of Peroneal Tendinopathy, Tears, and Subluxation
Melville, David M. , Taljanovic, Mihra S. , Gimber, Lana H., Sepich, Dustin, Miller, Matthew R. , Ahmad, Aamir , Latt, Leonard Daniel

Journal of Clinical Medicine | January 30, 2024 | Volume: 13 | Issue: 3 | Pages: 740

10.3390/jcm13030740 Get It

Suspected peroneal tendinopathy, tears, and subluxation are often confirmed preoperatively using magnetic resonance imaging (MRI) or diagnostic ultrasound (US). No study has directly compared the accuracy of these tests for the diagnosis of peroneal tendon pathology. The purpose of this study is to directly compare MRI and US to intraoperative findings in patients who underwent surgery for suspected peroneal pathology to determine the imaging diagnostic accuracy. Operative records and diagnostic images for 21 consecutive patients who had both MRI and US prior to surgery for suspected peroneal tendinopathy, tears, or subluxation were retrospectively reviewed. The results of this review are compared with the intraoperative findings to yield the sensitivity and specificity for each imaging modality. For the diagnosis of peroneal tendon tears, US was found to have a sensitivity of 88% and specificity of 100%, compared to 100% sensitivity and specificity for MRI. In the diagnosis of peroneal tendinopathy, both US and MRI had a sensitivity and specificity of 100%. In diagnosing peroneal subluxation, US was 100% sensitive compared to 66% for MRI, and both were 100% specific. In conclusion, US was found to be more effective in diagnosing peroneal subluxation and MRI was slightly more accurate in the diagnosis of peroneal tendon tears.