Al-Droubi, Tarek

Abstract Introduction Hydatid disease, caused by the parasite Echinococcus granulosus, is a prevalent parasitic infection found in various regions worldwide, including the Middle East, southern Europe, and Africa. Although hepatic and pulmonary involvements are well-documented, atypical presentations of the disease remain significant. Case Presentation This case report discusses a 32-year-old female patient who sought medical attention due to right hypochondrial pain, and pallor. Initial imaging revealed a hepatic cyst, but an incidental finding of a pericardial cyst further complicated the diagnosis. Subsequent evaluations confirmed the presence of a pericardial hydatid cyst, which is an uncommon manifestation of the disease. The patient presented with a multi-organ infection, which included a cardiac cyst—an unusual occurrence in hydatid disease. Additionally, the pericardial cyst was situated in the pericardium, a rare location, accounting for 2–10% of all cardiac cysts. Importantly, this cyst lacked myocardial involvement, adding to its uniqueness. Conclusion This case underscores the importance of considering hydatid disease in patients with non-specific symptoms, particularly in endemic regions, as timely diagnosis is crucial in preventing severe complications.