Citations 1
Effectiveness and Safety of Antiobesity Medications in Patients With Obesity and Inflammatory Bowel Disease
Pham, J. , Ghusn, Wissam , Acosta, Andrés , Loftus, Edward V. , Johnson, Amanda M. , Pham, Jonathan T , Ghusn, Wissam , Loftus, Edward V , Acosta, Andres
American Journal of Gastroenterology | October 9, 2023 | Volume: 119 | Issue: 6 | Pages: 1197-1200
INTRODUCTION: Limited data exist evaluating antiobesity medications (AOM) in patients with inflammatory bowel disease (IBD). METHODS: We performed a case-control study evaluating the effectiveness and safety of AOM in patients with IBD with obesity, matched to non-IBD controls. RESULTS: After 12 months, the case (n = 36) and control (n = 36) groups achieved similar percent total body weight loss of −6.9 ± 8.3 and −8.1 ± 7.0 ( P = 0.30), respectively. Side effect profiles were similar between groups. Seven patients experienced an IBD flare, all managed medically. DISCUSSION: AOM use in patients with IBD demonstrated similar effectiveness and safety when compared with that observed in the non-IBD population.