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Adams, Zoe H.

https://orcid.org/0000-0003-0187-0123

Mayo Clinic

University of Bristol

Citations 1

Aging in females is associated with changes in respiratory modulation of sympathetic nerve activity and blood pressure
Adams, Zoe H. , Blythe, Hazel , Charkoudian, Nisha , Joyner, Michael J. , Kendrick, Adrian , Nightingale, Angus K. , Abdala, Ana P. , Hart, Emma C. , Blythe, Hazel C , Curry, Timothy B. , Joyner, Michael J , Nightingale, Angus K , Abdala Sheikh, Ana P , Hart, Emma C

American Journal of Physiology-Heart and Circulatory Physiology | September 1, 2023 | Volume: 325 | Issue: 5 | Pages: H1108-H1117

10.1152/ajpheart.00226.2023 Get It

The current study demonstrates that respiratory modulation of sympathetic nerve activity (SNA) is reduced in healthy postmenopausal (PMF) versus premenopausal females (YF). Furthermore, respiratory sympathetic modulation was negatively related to resting blood pressure in postmenopausal females, such that blood pressure was greater in individual with less modulation. Reduced respiratory sympathetic modulation may have implications for the autonomic control of blood pressure in aging postmenopausal females, by contributing to age-related sympathetic activation and reducing acute, respiratory-linked blood pressure variation.