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Jones, David T.

https://orcid.org/0000-0002-4807-9833

Mayo Clinic

Mayo Clinic

Citations 339

IC‐P‐083: DIAGNOSTIC UTILITY OF [18F]AV‐1451 PET, FDG‐PET AND MRI TO DIFFERENTIATE THE THREE VARIANTS OF PRIMARY PROGRESSIVE APHASIA
Whitwell, Jennifer L., Martin, Peter R. , Graff‐Radford, Jonathan , Weigand, Stephen D. , Drubach, Daniel A., Petersen, Ronald C. , Lowe, Val J. , Josephs, Keith A. , Whitwell, Jennifer , Botha, Hugo , Schwarz, Christopher G. , Duffy, Joseph R. , Clark, Heather M. , Machulda, Mary M. , Senjem, Matthew L. , Utianski, Rene L. , Boeve, Bradley F. , Jones, David T. , Knopman, David S. , Jack, Clifford R.

Alzheimer's & Dementia | October 22, 2018 | Volume: 14 | Issue: 7S_Part_1 | Pages: No page available

10.1016/j.jalz.2018.06.2147 Get It

IC‐P‐028: VARIABILITY IN PDMN CONNECTIVITY AND RELATIVE HUBNESS IN COGNITIVELY NORMAL INDIVIDUALS PREDICT AMYLOID AND TAU DEPOSITION PATTERNS IN TYPICAL ALZHEIMER'S DISEASE
Graff‐Radford, Jonathan , Lowe, Val J. , Przybelski, Scott A. , Wiste, Heather J. , Gunter, Jeffrey L. , Petersen, Ronald C. , Botha, Hugo , Senjem, Matthew L. , Kantarci, Kejal , Boeve, Bradley F. , Knopman, David S. , Jack, Clifford R. , Jones, David T.

Alzheimer's & Dementia | October 22, 2018 | Volume: 14 | Issue: 7S_Part_1 | Pages: No page available

10.1016/j.jalz.2018.06.2092 Get It

P2‐430: MR SPECTROSCOPY FROM FRONTAL LOBE AND POSTERIOR CINGULATE GYRUS IN ASYMPTOMATIC AND SYMPTOMATIC MICROTUBULE‐ASSOCIATED PROTEIN TAU (MAPT) MUTATION CARRIERS
Chen, Qin , Brushaber, Danielle , Dheel, Christina, Fields, Julie A. , Forsberg, Leah K. , Gavrilova, Ralitza H. , Gearhart, Debra, Haley, Dana , Graff‐Radford, Jonathan , Graff‐Radford, Neill R. , Kraft, Ruth, Rademakers, Rosa , Syrjanen, Jeremy A. , Rosen, Howard J. , Boxer, Adam L. , Boeve, Bradley F. , Jones, David T. , Knopman, David S. , Lapid, Maria I. , Wszołek, Zbigniew K. , Kantarci, Kejal

Alzheimer's & Dementia | October 22, 2018 | Volume: 14 | Issue: 7S_Part_16 | Pages: No page available

10.1016/j.jalz.2018.06.1122 Get It

P1‐442: VARIABILITY IN PDMN CONNECTIVITY AND RELATIVE HUBNESS IN COGNITIVELY NORMAL INDIVIDUALS PREDICT AMYLOID AND TAU DEPOSITION PATTERNS IN TYPICAL ALZHEIMER'S DISEASE
Graff‐Radford, Jonathan , Lowe, Val J. , Przybelski, Scott A. , Wiste, Heather J. , Gunter, Jeffrey L. , Petersen, Ronald C. , Botha, Hugo , Senjem, Matthew L. , Kantarci, Kejal , Boeve, Bradley F. , Knopman, David S. , Jack, Clifford R. , Jones, David T.

Alzheimer's & Dementia | October 22, 2018 | Volume: 14 | Issue: 7S_Part_8 | Pages: No page available

10.1016/j.jalz.2018.06.451 Get It

P1‐420: ACCELERATED NEUROCHEMICAL CHANGES PRIOR TO PHENOCONVERSION TO FRONTOTEMPORAL LOBAR DEGENERATION IN PRESYMPTOMATIC MICROTUBULE‐ASSOCIATED PROTEIN TAU (MAPT) MUTATION CARRIERS: A LONGITUDINAL MRS STUDY
Chen, Qin, Tosakulwong, Nirubol , Lesnick, Timothy G. , Brushaber, Danielle , Dheel, Christina, Fields, Julie A. , Forsberg, Leah K. , Gavrilova, Ralitza H. , Gearhart, Debra, Haley, Dana , Gunter, Jeffrey L. , Graff‐Radford, Jonathan , Graff‐Radford, Neill R. , Kraft, Ruth, Rademakers, Rosa , Syrjanen, Jeremy A. , Rosen, Howard J. , Boxer, Adam L. , Chen, Qin, Boeve, Bradley F. , Jones, David T. , Knopman, David S. , Lapid, Maria I. , Wszołek, Zbigniew K. , Kantarci, Kejal

Alzheimer's & Dementia | October 22, 2018 | Volume: 14 | Issue: 7S_Part_8 | Pages: No page available

10.1016/j.jalz.2018.06.429 Get It

P1‐419: USING A BRAIN NETWORK APPROACH TO PREDICT GENETIC MUTATION IN INDIVIDUAL PATIENTS WITH FAMILIAL FRONTOTEMPORAL DEMENTIA
Touroutoglou, Alexandra , Brickhouse, Michael , Krivensky, Samantha, Getchell, Katelynn, Lucente, Diane , McGinnis, Scott M., Dickerson, Brad C., Rosen, Howard J. , Boxer, Adam L. , Bove, Jessica, Brushaber, Danielle , Coppola, Giovanni , Dheel, Christina, Dickinson, Susan, Faber, Kelley, Fields, Julie A. , Forsberg, Leah K. , Gavrilova, Ralitza H. , Gearhart, Debra, Ghoshal, Nupur , Graff‐Radford, Jonathan , Graff‐Radford, Neill R. , Grossman, Murray, Haley, Dana , Heuer, Hilary W. , Huey, Edward D. , Jones, Lynne C. , Karydas, Anna M., Kornak, John , Kramer, Joel H. , Mackenzie, Ian R. , Manoochehri, Masood , Pearlman, Rodney , Potter, Madeline, Rademakers, Rosa , Rankin, Katherine , Rascovsky, Katya, Sengdy, Pheth, Shaw, Leslie M. , Sutherland, Margaret , Syrjanen, Jeremy A. , Tatton, Nadine , Taylor, Joanne, Trojanowski, John Q. , Weıntraub, Sandra , Boeve, Bradley F. , Fong, Jamie , Foroud, Tatiana , Goldman, Jill , Hsiao, John , Irwin, David J. , Jones, David T. , Jones, Lynne, Kantarci, Kejal , Knopman, David S. , Kremers, Walter K. , Kukull, Walter A. , Lapid, Maria I. , Miller, Bruce L. , Toga, Arthur W. , Wszołek, Zbigniew K.

Alzheimer's & Dementia | October 22, 2018 | Volume: 14 | Issue: 7S_Part_8 | Pages: No page available

10.1016/j.jalz.2018.06.428 Get It

P1‐387: PRINCIPAL AXES OF PHENOTYPIC VARIABILITY IN ALZHEIMER'S DISEASE DERIVED FROM AN FDG‐PET BASED UNSUPERVISED MACHINE LEARNING ALGORITHM
Lowe, Val J. , Graff‐Radford, Jonathan , Parisi, Joseph E., Josephs, Keith A. , Therneau, Terry M. , Przybelski, Scott A. , Petersen, Ronald C. , Jones, David T. , Botha, Hugo , Murray, Melissa E. , Machulda, Mary M. , Senjem, Matthew L. , Kantarci, Kejal , Boeve, Bradley F. , Knopman, David S. , Jack, Clifford R.

Alzheimer's & Dementia | October 22, 2018 | Volume: 14 | Issue: 7S_Part_8 | Pages: No page available

10.1016/j.jalz.2018.06.395 Get It

P1‐281: NONLINEAR N‐SCORE ESTIMATION FOR ESTABLISHING COGNITIVE NORMS FROM THE NATIONAL ALZHEIMER'S COORDINATING CENTER (NACC) DATASET
Kornak, John , Fields, Julie A. , Farmer, Sarah, Rosen, Howard J. , Boxer, Adam L. , Bove, Jessica, Brushaber, Danielle , Coppola, Giovanni , Dheel, Christina, Dickerson, Brad C., Dickinson, Susan, Faber, Kelley, Forsberg, Leah K. , Gavrilova, Ralitza H. , Gearhart, Debra, Ghoshal, Nupur , Graff‐Radford, Jonathan , Graff‐Radford, Neill R. , Haley, Dana , Heuer, Hilary W. , Huey, Edward D. , Jones, Lynne C. , Karydas, Anna M., Kramer, Joel H. , Lucente, Diane , Mackenzie, Ian R. , Manoochehri, Masood , Pearlman, Rodney , Petrucelli, Leonard , Potter, Madeline, Rademakers, Rosa , Rankin, Katherine , Rascovsky, Katya, Sengdy, Pheth, Shaw, Leslie M. , Sutherland, Margaret , Syrjanen, Jeremy A. , Tatton, Nadine , Taylor, Joanne, Trojanowski, John Q. , Weıntraub, Sandra , Boeve, Bradley F. , Fong, Jamie , Foroud, Tatiana , Goldman, Jill , Grossman, Murray , Hsiao, John , Hsiung, Ging‐Yuek Robin , Irwin, David J. , Jones, David T. , Jones, Lynne, Kantarci, Kejal , Knopman, David S. , Kremers, Walter K. , Kukull, Walter A. , Lapid, Maria I. , Miller, Bruce L. , Toga, Arthur W. , Wszołek, Zbigniew K.

Alzheimer's & Dementia | October 22, 2018 | Volume: 14 | Issue: 7S_Part_7 | Pages: No page available

10.1016/j.jalz.2018.06.287 Get It

Imaging correlations of tau, amyloid, metabolism, and atrophy in typical and atypical Alzheimer's disease
Whitwell, Jennifer L. , Graff‐Radford, Jonathan, Tosakulwong, Nirubol , Weigand, Stephen D. , Senjem, Matthew L. , Spychalla, Anthony J., Vemuri, Prashanthi , Drubach, Daniel A., Ertekin‐Taner, Nilüfer , Petersen, Ronald C. , Lowe, Val J. , Jack, Clifford R. , Josephs, Keith A. , Jack, Clifford R , Vemuri, Prashanthi , Senjem, Matthew L , Graff‐Radford, Jonathan , Machulda, Mary M. , Jones, David T. , Knopman, David S. , Boeve, Bradley F.

Alzheimer's & Dementia | March 30, 2018 | Volume: 14 | Issue: 8 | Pages: 1005-1014

10.1016/j.jalz.2018.02.020 Get It

Abstract Introduction Neuroimaging modalities can measure different aspects of the disease process in Alzheimer's disease, although the relationship between these modalities is unclear. Methods We assessed subject‐level regional correlations between tau on [ 18 F]AV‐1451 positron emission tomography (PET), β amyloid on Pittsburgh compound B PET, hypometabolism on [ 18 F] fluorodeoxyglucose PET, and cortical thickness on magnetic resonance imaging in 96 participants with typical and atypical Alzheimer's disease presentations. We also assessed how correlations between modalities varied according to age, presenting syndrome, tau‐PET severity, and asymmetry. Results [ 18 F]AV‐1451 uptake showed the strongest regional correlation with hypometabolism. Correlations between [ 18 F]AV‐1451 uptake and both hypometabolism and cortical thickness were stronger in participants with greater cortical tau severity. In addition, age, tau asymmetry, and clinical diagnosis influenced the strength of the correlation between [ 18 F]AV‐1451 uptake and cortical thickness. Discussion These findings support a close relationship between tau and hypometabolism in Alzheimer's disease but show that correlations between neuroimaging modalities vary across participants.
Longitudinal tau PET in ageing and Alzheimer’s disease
Jack, Clifford R. , Wiste, Heather J. , Lowe, Val J. , Senjem, Matthew L. , Vemuri, Prashanthi , Weigand, Stephen D. , Therneau, Terry M. , Knopman, D. S., Gunter, Jeffrey L. , Graff‐Radford, Jonathan , Kantarci, Kejal , Roberts, Rosebud O., Petersen, Ronald C. , Knopman, Dave S, Jack, Clifford R , Vemuri, Prashanthi , Senjem, Matthew L , Kantarci, Kejal , Schwarz, Christopher G. , Jones, David T. , Mielke, Michelle M. , Machulda, Mary M.

Brain | February 22, 2018 | Volume: 141 | Issue: 5 | Pages: 1517-1528

10.1093/brain/awy059 Get It