Citations 2
Failure of mecA/mecC PCR Testing to Accurately Predict Oxacillin Resistance in a Patient with Staphylococcus aureus Infective Endocarditis
Hess, Kyle A., Kooda, Kirstin , Shirley, Joshua D. , Schuetz, Audrey N. , Saleh, Omar Abu , Stevens, Ryan W. , Abu Saleh, Omar , Schuetz, Audrey N , Stevens, Ryan W
Antimicrobial Agents and Chemotherapy | June 21, 2023 | Volume: 67 | Issue: 10 | Pages: No page available
Genotypic testing for mecA / mecC is heavily relied upon for rapid optimization of antimicrobial therapy in infections due to Staphylococcus aureus . Little is known regarding optimal reporting and/or therapy for patients demonstrating lack of genotypic evidence of mecA or mecC but phenotypic oxacillin resistance.
Retrospective Evaluation of the Association of Oxacillin MIC on Acute Treatment Outcomes with Cefazolin and Antistaphylococcal Penicillins in Methicillin-Susceptible Staphylococcus aureus Bacteremia
Hess, Kyle A., Kooda, Kirstin , Shulha, Jennifer A., Mara, Kristin C. , Mara, Kristin, Go, John R, Mara, Kristin C , Shulha, Jenny , Go, John Raymond , Fida, Madiha , DeSimone, Daniel C. , Stevens, Ryan W.
Journal of Clinical Microbiology | March 29, 2023 | Volume: 61 | Issue: 4 | Pages: No page available
Antistaphylococcal penicillins (ASP) and cefazolin are first-line treatment of methicillin-susceptible Staphylococcus aureus (MSSA) bacteremia. Borderline oxacillin resistance (i.e., oxacillin MICs 1-8 μg/mL) is observed in strains hyperproducing beta-lactamases.