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Elsbernd, Paul

https://orcid.org/0000-0001-7572-3615

Mayo Clinic

Mayo Clinic in Arizona

Citations 4

Interleukin-6 Inhibition with Tocilizumab for Relapsing MOG-IgG Associated Disorder (11)
Elsbernd, Paul , Wingerchuk, Dean M. , Carter, Jonathan , Hoffmann, William, Carter, Jonathan

Neurology | December 7, 2023 | Volume: 96 | Issue: 15_supplement | Pages: No page available

10.1212/wnl.96.15_supplement.11 Get It

Cerebral cortical encephalitis in Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease (P16-1.002)
Sánchez, Cristina Valencia, Chen, John , Tillema, Jan‐Mendelt , Lucchinetti, Claudia F. , Montalvo, Mayra , Elsbernd, Paul , López‐Chiriboga, A. Sebastian , Budhram, Adrian , Sechi, Elia , Kunchok, Amy , Dubey, Divyanshu , Pittock, Sean J. , Flanagan, Eoin P.

Neurology | December 6, 2023 | Volume: 98 | Issue: 18_supplement | Pages: No page available

10.1212/wnl.98.18_supplement.2497 Get It

Cerebral Cortical Encephalitis in Myelin Oligodendrocyte Glycoprotein Antibody‐Associated Disease
Guo, Yong , Krecke, Karl N. , Chen, John J. , Redenbaugh, Vyanka , Montalvo, Mayra , Elsbernd, Paul , Tillema, Jan‐Mendelt , López‐Chiriboga, A. Sebastian , Budhram, Adrian , Kunchok, Amy , Dubey, Divyanshu , Pittock, Sean J. , Lucchinetti, Claudia F. , Dubey, Divyanshu , Valencia-Sánchez, Cristina , Pittock, S J , Flanagan, E P , Lopez-Chiriboga, A Sebastian , Budhram, Adrian , Dubey, Divyanshu , Pittock, Sean J , Chen, John J , Dubey, Divyanshu , Valencia Sanchez, Cristina , Sechi, Elia , Flanagan, Eoin P.

Annals of Neurology | November 14, 2022 | Volume: 93 | Issue: 2 | Pages: 297-302

10.1002/ana.26549 Get It

Cerebral cortical encephalitis (CCE) is a recently described myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) phenotype. In this observational retrospective study, we characterized 19 CCE patients (6.7% of our MOGAD cohort). Headache (n = 15, 79%), seizures (n = 13, 68%), and encephalopathy (n = 12, 63%) were frequent. Magnetic resonance imaging revealed unilateral (n = 12, 63%) or bilateral (n = 7, 37%) cortical T2 hyperintensity and leptomeningeal enhancement (n = 17, 89%). N‐Methyl‐D‐aspartate receptor autoantibodies coexisted in 2 of 15 tested (13%). CCE pathology (n = 2) showed extensive subpial cortical demyelination (n = 2), microglial reactivity (n = 2), and inflammatory infiltrates (perivascular, n = 1; meningeal, n = 1). Most received high‐dose steroids (n = 17, 89%), and all improved, but 3 had CCE relapses. This study highlights the CCE spectrum and provides insight into its pathogenesis. ANN NEUROL 2023;93:297–302