Citations 2
Computed tomography perfusion stroke mimics on RAPID commercial software: A case-based review
Ahmed, Amara, Hamam, Omar , Niri, Sanaz Ghaderi, Oeltzchner, Georg, Elmandouh, Omar, Garg, Tushar , Intrapiromkul, Jarunee, Intrapiromkul, Jarunee , Yedavalli, Vivek
Brain Circulation | June 30, 2023 | Volume: 9 | Issue: 2 | Pages: 68-76
Acute ischemic stroke (AIS) is a leading cause of morbidity worldwide and can present with nonspecific symptoms, making diagnosis difficult. Many neurologic diseases present similarly to stroke; stroke mimics account for up to half of all hospital admissions for stroke. Stroke therapies carry risk, so accurate diagnosis of AIS is crucial for prompt treatment and prevention of adverse outcomes for patients with stroke mimics. Computed tomography (CT) perfusion techniques have been used to distinguish between nonviable tissue and penumbra. RAPID is an operator-independent, automated CT perfusion imaging software that can aid clinicians in diagnosing strokes quickly and accurately. In this case-based review, we demonstrate the applications of RAPID in differentiating between strokes and stroke mimics.
Baseline Characteristics Associated with Good Collateral Status Using Hypoperfusion Index as an Outcome
Hamam, Omar , Garg, Tushar , Elmandouh, Omar, Wang, Richard , Aslan, Alperen , Ahmed, Amara, Moustafa, Abdallah , Yedavalli, Vivek , Yedavalli, Vivek S
Tomography | July 25, 2022 | Volume: 8 | Issue: 4 | Pages: 1885-1894
Up to 30% of ischemic stroke cases are due to large vessel occlusion (LVO), causing significant morbidity. Studies have shown that the collateral circulation of patients with acute ischemic stroke (AIS) secondary to LVO can predict their clinical and radiological outcomes. The aim of this study is to identify baseline patient characteristics that can help predict the collateral status of these patients for improved triage. In this IRB approved retrospective study, consecutive patients presenting with AIS secondary to anterior circulation LVO were identified between September 2019 and August 2021. The baseline patient characteristics, laboratory values, imaging features and outcomes were collected using a manual chart review. From the 181 consecutive patients initially reviewed, 54 were confirmed with a clinical diagnosis of AIS and anterior circulation LVO. In patients with poor collateral status, the body mass index (BMI) was found to be significantly lower compared to those with good collateral status (26.4 ± 5.6 vs. 31.7 ± 12.3; p = 0.045). BMI of >35 kg/m2 was found to predict the presence of good collateral status. Age was found to be significantly higher (70.5 ± 9.6 vs. 58.9 ± 15.6; p = 0.034) in patients with poor collateral status and M1 strokes associated with older age and BMI.