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Chomont, Nicolas

https://orcid.org/0000-0001-9747-5018

Mayo Clinic

Centre Hospitalier de l’Université de Montréal

Citations 1

Detecting Sources of Immune Activation and Viral Rebound in HIV Infection
Wietgrefe, Stephen W. , Duan, Lijie, Anderson, Jodi, Marqués, Guillermo , Sanders, Mark A , Cummins, Nathan W. , Karn, Jonathan , Pagliuzza, Amélie , Chomont, Nicolas , Sannier, Gérémy , Kaufmann, Daniel E. , Zuck, Paul, Howell, Bonnie J. , Reilly, Cavan , Herschhorn, Alon , Schacker, Timothy W. , Haase, Ashley T. , Cummins, Nathan W , Badley, Andrew D. , Dobrowolski, Curtis N. , Dubé, Mathieu , Wu, Guoxin

Journal of Virology | July 20, 2022 | Volume: 96 | Issue: 15 | Pages: No page available

10.1128/jvi.00885-22 Get It

Anti-retroviral therapy (ART) has greatly improved the quality and length of life for people living with HIV, but immune activation does not normalize during ART, and persistent immune activation has been linked to increased morbidity and mortality. We report a comparison of assays of two potential sources of immune activation during ART: rare cells producing HIV and the virus’ major viral protein, p24, benchmarked on a cell model of active and latent infections and a method to visualize HIV-producing cells.