Citations 1
A Novel USP25::PDGFRA Gene Fusion in a 78 Year Old Patient with a Myeloid Neoplasm
Dalland, Joanna , Blackburn, Patrick R. , Reichard, Kaaren K. , Johnson, Sarah H. , Smadbeck, James B. , Vasmatzis, George , Hoppman, Nicole L., Xu, Xinjie, Greipp, Patricia T. , Peterson, Jess F. , Dalland, Joanna C , Peterson, Jess F , Greipp, Patricia T , Baughn, Linda B.
Laboratory Medicine | January 27, 2022 | Volume: 53 | Issue: 5 | Pages: e134-e138
Abstract The World Health Organization category of myeloid/lymphoid neoplasms with eosinophilia and PDGFRA rearrangements is composed of a heterogeneous group of neoplasms that can present as a myeloproliferative neoplasm, acute myeloid leukemia, myeloid sarcoma, or lymphoblastic leukemia/lymphoma. The overall outcome of these neoplasms is favorable with imatinib therapy. Herein, we describe an adult female patient with a myeloid neoplasm accompanied by eosinophilia and a novel USP25::PDGFRA gene fusion.