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Wang, Benjamin

https://orcid.org/0000-0002-9492-1489

Mayo Clinic

Mayo Clinic in Florida

Citations 1

Adult-onset Still’s disease after environmental exposure while working in Africa
Gilbert, Emily, Wang, Benjamin , Gilbert, Emily L

BMJ Case Reports | October 28, 2021 | Volume: 14 | Issue: 10 | Pages: e244156

10.1136/bcr-2021-244156 Get It

Adult-onset Still’s disease (AOSD) is characterised by a constellation of systemic inflammatory symptoms and typical laboratory findings like hyperferritinaemia. A high index of suspicion is needed to identify patients as diagnosis is primarily clinical and significant morbidity can result from delayed diagnosis. While AOSD may be self-limited, some patients experience flares over years and require more aggressive treatment approaches. Aetiology is unknown but can be triggered by viral infections and other environmental factors in a susceptible genetic host. We present a case of AOSD triggered after exposure to a sap-like liquid while working in Africa. This inciting event occurred as part of a hostile act towards the patient and involved medicinal practices traditional to the area. Our case highlights the more chronic course of AOSD, which requires escalating biological treatment to avoid long-term corticosteroids, as well as the juncture between traditional and modern medical practices.