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Totten, Katherine M. C.

https://orcid.org/0000-0002-8181-1176

Mayo Clinic

Mayo Clinic

Citations 4

Considerations for the Use of Phage Therapy in Clinical Practice
Suh, Gina A. , Lodise, Thomas P. , Tamma, Pranita D. , Knisely, Jane M., Alexander, Jose, Aslam, Saima, Barton, Karen D., Bizzell, Erica, Totten, Katherine M. C. , Campbell, Joseph L., Chan, Benjamin K., Cunningham, Scott A., Goodman, Katherine E., Greenwood-Quaintance, Kerryl E., Harris, Anthony D., Hesse, Shayla , Maresso, Anthony, Nussenblatt, Veronique, Pride, David , Rybak, Michael J. , Sund, Zoe, Tyne, Daria Van , Patel, Robin , Group, for the Antibacterial Resistance Leadership, Barton, Karen D. , van Duin, David , Van Tyne, Daria , Patel, Robin , Tamma, Pranita D , Suh, Gina A , Lodise, Thomas P. , Knisely, Jane M., Alexander, Jose, Aslam, Saima, Bizzell, Erica, Totten, Katherine M. C. , Campbell, Joseph L., Chan, Benjamin K., Cunningham, Scott A., Goodman, Katherine E., Greenwood-Quaintance, Kerryl E., Harris, Anthony D., Hesse, Shayla , Maresso, Anthony, Nussenblatt, Veronique, Pride, David , Rybak, Michael J , Sund, Zoe, Group, for the Antibacterial Resistance Leadership

Antimicrobial Agents and Chemotherapy | January 18, 2022 | Volume: 66 | Issue: 3 | Pages: No page available

10.1128/aac.02071-21 Get It

Increasing antimicrobial resistance and medical device-related infections have led to a renewed interest in phage therapy as an alternative or adjunct to conventional antimicrobials. Expanded access and compassionate use cases have risen exponentially but have varied widely in approach, methodology, clinical situations in which phage therapy might be considered, dosing, route of administration, and outcomes.
Phage Activity against Planktonic and Biofilm Staphylococcus aureus Periprosthetic Joint Infection Isolates
Totten, Katherine M. C. , Patel, Robin , Patel, Robin

Antimicrobial Agents and Chemotherapy | October 18, 2021 | Volume: 66 | Issue: 1 | Pages: No page available

10.1128/aac.01879-21 Get It

We recently reported the successful treatment of a case of periprosthetic joint infection (PJI) with phage. Phage activity against bacteria causing PJI has not been systematically evaluated.
Biological challenges of phage therapy and proposed solutions: a literature review
Caflisch, Katherine M., Patel, Robin , Totten, Katherine M. C. , Patel, Robin , Suh, Gina A. , Totten, Katherine M. C.

Expert Review of Anti-infective Therapy | November 16, 2019 | Volume: 17 | Issue: 12 | Pages: 1011-1041

10.1080/14787210.2019.1694905 Get It

Implications of Bacteriophage- and Bacteriophage Component-Based Therapies for the Clinical Microbiology Laboratory
Caflisch, Katherine M., Patel, Robin , Totten, Katherine M. C. , Patel, Robin , Totten, Katherine M. C.

Journal of Clinical Microbiology | May 23, 2019 | Volume: 57 | Issue: 8 | Pages: No page available

10.1128/jcm.00229-19 Get It

Treatment of bacterial infections is increasingly challenged by resistance to currently available antibacterial agents. Not only are such agents less likely to be active today than they were in the past, but their very use has selected for and continues to select for further resistance. Additional strategies for the management of bacterial illnesses must be identified. In this review, bacteriophage-based therapies are presented as one promising approach.