Citations 1
Accuracy of a Rapid Multiplex Polymerase Chain Reaction Plus a Chromogenic Phenotypic Test Algorithm for Detection of Extended-Spectrum β-Lactamase and Carbapenemase-Producing Gram-Negative Bacilli in Positive Blood Culture Bottles
Ong, Sean Wei Xiang , Hon, Pei Yun, Wee, Sharon , Chia, Jonathan W. Z., Mendis, Shehara M, Izharuddin, Ezlyn, Lin, Ray Junhao, Chia, Po Ying , Sim, Rees Chin Swee, Chen, Mark , Lye, David Chien , Teng, Christine B. , Tambyah, Paul Anantharajah , Banerjee, Ritu , Patel, Robin , De, Partha Pratim, Chen, Mark I-Cheng , Chow, Angela , Patel, Robin , Kline, Susan , Yoong, Joanne , Vasoo, Shawn
Clinical Infectious Diseases | September 21, 2021 | Volume: 74 | Issue: 10 | Pages: 1850-1854
Abstract We studied the performance of an algorithm combining multiplex polymerase chain reaction with phenotypic detection of extended-spectrum β-lactamases and carbapenemases directly from positive blood culture bottles in patients with gram-negative bacteremia and found good concordance with routine cultures. Such an algorithm may be a tool to improve time to optimal therapy in patients with gram-negative bacteremia.