Citations 3
Clinical and Infection Prevention Applications of Severe Acute Respiratory Syndrome Coronavirus 2 Genotyping: an Infectious Diseases Society of America/American Society for Microbiology Consensus Review Document
Greninger, Alexander L. , Bard, Jennifer Dien , Colgrove, Robert C. , Graf, Erin H. , Hanson, Kimberly E. , Hayden, Mary K. , Humphries, Romney M. , Lowe, Christopher F. , Pillai, Dylan R. , Rhoads, Daniel D. , Yao, Joseph D. , Lee, Francesca M, Dien Bard, Jennifer , Humphries, Romney , Hanson, Kimberly , Rhoads, Daniel D , Greninger, Alexander L , Graf, Erin H , Miller, Melissa B.
Journal of Clinical Microbiology | November 3, 2021 | Volume: 60 | Issue: 1 | Pages: No page available
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged into a world of maturing pathogen genomics, with more than 2 million genomes sequenced at the time of writing. The rise of more transmissible variants of concern that impact vaccine and therapeutic effectiveness has led to widespread interest in SARS-CoV-2 evolution.
Clinical and Infection Prevention Applications of Severe Acute Respiratory Syndrome Coronavirus 2 Genotyping: An Infectious Diseases Society of America/American Society for Microbiology Consensus Review Document
Greninger, Alexander L. , Bard, Jennifer Dien , Colgrove, Robert C. , Hayden, Mary K. , Humphries, Romney M. , Lowe, Christopher F. , Pillai, Dylan R. , Rhoads, Daniel D. , Yao, Joseph D. , Lee, Francesca M, Graf, Erin H. , Humphries, Romney , Rhoads, Daniel D , Greninger, Alexander L , Hanson, Kimberly E. , Miller, Melissa B.
Clinical Infectious Diseases | September 8, 2021 | Volume: 74 | Issue: 8 | Pages: 1496-1502
Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged into a world of maturing pathogen genomics, with >2 million genomes sequenced at this writing. The rise of more transmissible variants of concern that affect vaccine and therapeutic effectiveness has led to widespread interest in SARS-CoV-2 evolution. Clinicians are also eager to take advantage of the information provided by SARS-CoV-2 genotyping beyond surveillance purposes. Here, we review the potential role of SARS-CoV-2 genotyping in clinical care. The review covers clinical use cases for SARS-CoV-2 genotyping, methods of SARS-CoV-2 genotyping, assay validation and regulatory requirements, clinical reporting for laboratories, and emerging issues in clinical SARS-CoV-2 sequencing. While clinical uses of SARS-CoV-2 genotyping are currently limited, rapid technological change along with a growing ability to interpret variants in real time foretell a growing role for SARS-CoV-2 genotyping in clinical care as continuing data emerge on vaccine and therapeutic efficacy.
Envisioning Future Urinary Tract Infection Diagnostics
Patel, Robin , Bard, Jennifer Dien , May, Larissa, Lee, Francesca M, Hayden, Mary K. , Doernberg, Sarah D B, Haake, David A. , Grigoryan, Larissa, Tsalik, Ephraim L. , Hanson, Kimberly E. , Grigoryan, Larissa , Patel, Robin , Hanson, Kimberly , Grigoryan, Larissa , Polage, Christopher R. , Fabre, Valeria , Doernberg, Sarah B. , Trautner, Barbara W.
Clinical Infectious Diseases | August 31, 2021 | Volume: 74 | Issue: 7 | Pages: 1284-1292
Abstract Urinary tract infections (UTIs) are among the most common bacterial infections in the United States and are a major driver of antibiotic use, both appropriate and inappropriate, across healthcare settings. Novel UTI diagnostics are a strategy that might enable better UTI treatment. Members of the Antibacterial Resistance Leadership Group Laboratory Center and the Infectious Diseases Society of America Diagnostics Committee convened to envision ideal future UTI diagnostics, with a view towards improving delivery of healthcare, patient outcomes and experiences, and antibiotic use, addressing which types of UTI diagnostics are needed and how companies might approach development of novel UTI diagnostics.