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Baskerville, Victoria

Mayo Clinic

Mayo Clinic

Citations 1

Nuclear accumulation of CHMP7 initiates nuclear pore complex injury and subsequent TDP-43 dysfunction in sporadic and familial ALS
Coyne, Alyssa N. , Baskerville, Victoria, Zaepfel, Benjamin L. , Dickson, Dennis W. , Rigo, Frank , Bennett, Frank , Lusk, C. Patrick , Rothstein, Jeffrey D. , Dickson, Dennis W , Coyne, Alyssa N , Rothstein, Jeffrey D

Science Translational Medicine | July 28, 2021 | Volume: 13 | Issue: 604 | Pages: No page available

10.1126/scitranslmed.abe1923 Get It

Nuclear accumulation of CHMP7 leads to multiple cellular pathologies that can be mitigated via CHMP7 ASOs in familial and sporadic ALS iPSNs.