Mayo Clinic - AuthorCitation

Steroid-sparing maintenance immunotherapy for MOG-IgG associated disorder

Chen, John J. , Bhatti, M. Tariq , Jitprapaikulsan, Jiraporn , Dubey, Divyanshu , López‐Chiriboga, A. Sebastian , Fryer, James P., Weinshenker, Brian G. , Tillema, Jan‐Mendelt , Lennon, Vanda A. , Lucchinetti, Claudia F. , Kunchok, Amy , Lee, Michael S. , Bennett, Jeffrey L. , Pelak, Victoria S. , Stavern, Gregory Van , Eggenberger, Eric , Acierno, Marie D, Wingerchuk, Dean M. , Lam, Byron L., Moss, Heather E. , Beres, Shannon , Gilbert, Aubrey L. , Shah, Veeral, Armstrong, Grayson W. , Heidary, Gena , Cestari, Dean M. , Pittock, Sean J. , Jitprapaikulsan, Jiraporn , Lopez Chiriboga, Alfonso Sebastian S, Weinshenker, Brian G , McClelland, Collin M, Van Stavern, Gregory, Adesina, Ore-Ofe O, Eggenberger, Eric R, Moss, Heather, Armstrong, Grayson, Pittock, S J , Bennett, Jeffrey L , Pittock, Sean J , Chen, John J , Dubey, Divyanshu , Moss, Heather E , Flanagan, Eoin P. , McKeon, Andrew , McClelland, Collin M. , Adesina, Ore-ofe O. , Shah, Veeral S. , Stiebel‐Kalish, Hadas

Neurology | June 18, 2020 | Volume: 95 | Issue: 2 | Pages: No page available

10.1212/wnl.0000000000009758

Clinical utility of AQP4-IgG titers and measures of complement-mediated cell killing in NMOSD

Jitprapaikulsan, Jiraporn , Fryer, James P., Majed, Masoud , Jenkins, Sarah M. , Cabre, Philippe, Hinson, Shannon R., Weinshenker, Brian G. , Mandrekar, Jay , Chen, John J. , Lucchinetti, Claudia F. , Jiao, Yujuan , Segan, Jessica, Schmeling, John E., Mills, John R. , Pittock, Sean J. , Smith, Carin Y. , Weinshenker, Brian G , Pittock, S J , Chen, John J , Flanagan, Eoin P. , McKeon, Andrew

Neurology Neuroimmunology & Neuroinflammation | May 28, 2020 | Volume: 7 | Issue: 4 | Pages: No page available

10.1212/nxi.0000000000000727

Autologous nonmyeloablative hematopoietic stem cell transplantation for neuromyelitis optica

Burt, Richard K. , Balabanov, Roumen , Han, Xiaoqiang , Burns, Carol, Gastala, Joseph B. , Jovanovic, Borko, Helenowski, Irene , Jitprapaikulsan, Jiraporn , Fryer, James P., Pittock, Sean J. , Gastala, Joseph , Pittock, S J

Neurology | October 2, 2019 | Volume: 93 | Issue: 18 | Pages: No page available

10.1212/wnl.0000000000008394

Clinical, Radiologic, and Prognostic Features of Myelitis Associated With Myelin Oligodendrocyte Glycoprotein Autoantibody

Dubey, Divyanshu , Pittock, Sean J. , Krecke, Karl N. , Morris, Padraig P., Sechi, Elia , Zalewski, Nicholas L. , Weinshenker, Brian G. , Shosha, Eslam , Lucchinetti, Claudia F. , Fryer, James P., López‐Chiriboga, A. Sebastian , Chen, John C. , Jitprapaikulsan, Jiraporn , McKeon, Andrew , Gadoth, Avi , Tillema, Jan‐Mendelt , Naddaf, Elie , Messacar, Kevin , Chen, John J. , Patterson, Marc C. , Pittock, S J , Weinshenker, Brian G , Naddaf, Elie , McKeon, Andrew , Chen, John J , Sechi, Elia , Dubey, Divyanshu , Keegan, B. Mark , Tyler, Kenneth L. , Flanagan, Eoin P.

JAMA Neurology | December 21, 2018 | Volume: 76 | Issue: 3 | Pages: 301

10.1001/jamaneurol.2018.4053

Association of MOG-IgG Serostatus With Relapse After Acute Disseminated Encephalomyelitis and Proposed Diagnostic Criteria for MOG-IgG–Associated Disorders

López‐Chiriboga, A. Sebastian , Majed, Masoud , Fryer, James P., Dubey, Divyanshu , McKeon, Andrew , Jitprapaikulsan, Jiraporn , Kothapalli, Naga Pradyumna, Tillema, Jan‐Mendelt , Chen, John J. , Weinshenker, Brian G. , Wingerchuk, Dean M. , Sagen, Jessica, Gadoth, Avi , Lennon, Vanda A. , Lucchinetti, Claudia F. , Pittock, Sean J. , Fryer, James, Kothapalli, Naga, Wingerchuk, Dean, Lucchinetti, Claudia, Pittock, S J , Weinshenker, Brian G , McKeon, Andrew , Chen, John J , Dubey, Divyanshu , Flanagan, Eoin P. , Keegan, B. Mark

JAMA Neurology | July 16, 2018 | Volume: 75 | Issue: 11 | Pages: 1355

10.1001/jamaneurol.2018.1814

Autoimmune septin-5 cerebellar ataxia

Honorat, Josephe A., López‐Chiriboga, A. Sebastian , Kryzer, Thomas J., Fryer, James P., Devine, Michelle F., Flores, Angela, Lennon, Vanda A. , Pittock, Sean J. , McKeon, Andrew , Devine, Michelle, Pittock, S J , McKeon, Andrew

Neurology Neuroimmunology & Neuroinflammation | July 9, 2018 | Volume: 5 | Issue: 5 | Pages: No page available

10.1212/nxi.0000000000000474

Novel Glial Targets and Recurrent Longitudinally Extensive Transverse Myelitis

Jitprapaikulsan, Jiraporn , López‐Chiriboga, A. Sebastian , Fryer, James P., McKeon, Andrew , Weinshenker, Brian G. , Pittock, Sean J. , Pittock, S J , Weinshenker, Brian G , McKeon, Andrew , Flanagan, Eoin P.

JAMA Neurology | April 28, 2018 | Volume: 75 | Issue: 7 | Pages: 892

10.1001/jamaneurol.2018.0805

Prevalence of Myelin Oligodendrocyte Glycoprotein and Aquaporin-4–IgG in Patients in the Optic Neuritis Treatment Trial

Chen, John J. , Majed, Masoud , Jitprapaikulsan, Jiraporn , Fryer, James P., Leavitt, Jacqueline A., McKeon, Andrew , Pittock, Sean J. , Pittock, S J , McKeon, Andrew , Chen, John J , Tobin, W. Oliver , Flanagan, Eoin P.

JAMA Ophthalmology | February 22, 2018 | Volume: 136 | Issue: 4 | Pages: 419

10.1001/jamaophthalmol.2017.6757

Clinical utility of testing AQP4-IgG in CSF

Majed, Masoud , Fryer, James P., McKeon, Andrew , Lennon, Vanda A. , Pittock, Sean J. , Pittock, S J , McKeon, Andrew

Neurology Neuroimmunology & Neuroinflammation | April 21, 2016 | Volume: 3 | Issue: 3 | Pages: No page available

10.1212/nxi.0000000000000231

Epidemiology of aquaporin‐4 autoimmunity and neuromyelitis optica spectrum

Flanagan, Eoin P. , Cabre, Philippe, Weinshenker, Brian G. , Sauver, Jennifer L. St. , Jacobson, Debra J., Majed, Masoud , Lennon, Vanda A. , Lucchinetti, Claudia F. , McKeon, Andrew , Matiello, Marcelo , Kale, Nilifur, Wingerchuk, Dean M. , Mandrekar, Jay , Sagen, Jessica, Fryer, James P., Robinson, Angala Borders, Pittock, Sean J. , Sagen, Jessica A., Pittock, S J , Flanagan, E P , Weinshenker, Brian G , St Sauver, Jennifer L , McKeon, Andrew

Annals of Neurology | February 18, 2016 | Volume: 79 | Issue: 5 | Pages: 775-783

10.1002/ana.24617

ObjectiveNeuromyelitis optica (NMO) and its spectrum disorders (NMOSD) are inflammatory demyelinating diseases (IDDs) with a specific biomarker, aquaporin‐4–immunoglobulin G (AQP4‐IgG). Prior NMO/NMOSD epidemiological studies have been limited by lack of AQP4‐IgG seroprevalence assessment, absence of population‐based USA studies, and under‐representation of blacks. To overcome these limitations, we sought to compare NMO/NMOSD seroepidemiology across 2 ethnically divergent populations.MethodsWe performed a population‐based comparative study of the incidence (2003–2011) and prevalence (on December 31, 2011) of NMO/NMOSD and AQP4‐IgG seroincidence and seroprevalence (sera collected in 80–84% of IDD cases) among patients with IDD diagnosis in Olmsted County, Minnesota (82% white [Caucasian]) and Martinique (90% black [Afro‐Caribbean]). AQP4‐IgG was measured by M1 isoform fluorescence‐activated cell‐sorting assays.ResultsThe age‐ and sex‐adjusted incidence (7.3 vs 0.7/1,000,000 person‐years [p < 0.01]) and prevalence (10 vs 3.9/100,000 [p = 0.01]) in Martinique exceeded that in Olmsted County. The AQP4‐IgG age‐ and sex‐adjusted seroincidence (6.5 vs 0.7/1,000,000 person‐years [p < 0.01]) and seroprevalence (7.9 vs 3.3/100,000 [p = 0.04]) were also higher in Martinique than Olmsted County. The ethnicity‐specific prevalence was similar in Martinique and Olmsted County: 11.5 and 13/100,000 in blacks, and 6.1 and 4.0/100,000 in whites, respectively. NMO/NMOSD represented a higher proportion of IDD cases in Martinique than Olmsted County (16% vs 1.4%; p < 0.01). The onset age (median = 35–37 years) and female:male distribution (5–9:1) were similar across both populations; 60% of prevalent cases were either blind in 1 eye, dependent on a gait aid, or both.InterpretationThis study reports the highest prevalence of NMO/NMOSD in any population (10/100,000 in Martinique), estimates it affects 16,000 to 17,000 in the USA (higher than previous predictions), and demonstrates it disproportionately affects blacks. Ann Neurol 2016;79:775–783

Fryer, James P.

Citations 45