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Dugger, Brittany N.

https://orcid.org/0000-0003-2141-8855

Mayo Clinic

University of California, Davis

Citations 52

O2–10–06: Neuropathological outcome of prospectively followed normal elderly brain bank volunteers
Hentz, Joseph G. , Adler, Charles, Shill, Holly A. , Jacobson, Sandra A. , Caviness, John N., Belden, Christine M. , Driver‐Dunckley, Erika, Davis, Kathryn, Sue, Lucia I., Beach, Thomas G. , Dugger, Brittany N. , Sabbagh, Marwan Noel , Driver‐Dunckley, Erika

Alzheimer's & Dementia | October 9, 2013 | Volume: 9 | Issue: 4S_Part_8 | Pages: No page available

10.1016/j.jalz.2013.04.194 Get It

Quantitative Appraisal of Ventricular Cerebrospinal Fluid Biomarkers in Neuropathologically Diagnosed Parkinson's Disease Cases Lacking Alzheimer's Disease Pathology
Maarouf, Chera L., Beach, Thomas G., Malek‐Ahmadi, Michael , Kokjohn, Tyler A., Dugger, Brittany N. , Walker, Douglas G. , Shill, Holly A. , Jacobson, Sandra A. , Roher, Alex E., Adler, Charles H. , Sabbagh, Marwan Noel , Dugger, Brittany N

Biomarker Insights | March 12, 2013 | Volume: 8 | Issue: No issue available | Pages: BMI.S11422

10.4137/bmi.s11422 Get It

Identifying biomarkers that distinguish Parkinson's disease (PD) from normal control (NC) individuals has the potential to increase diagnostic sensitivity for the detection of early-stage PD. A previous proteomic study identified potential biomarkers in postmortem ventricular cerebrospinal fluid (V-CSF) from neuropathologically diagnosed PD subjects lacking Alzheimer's disease (AD) neuropathology. In the present study, we assessed these biomarkers as well as p-tau 181 , Aβ42, and S100B by ELISA in PD (n = 43) and NC (n = 49) cases. The p-tau 181 /Aβ42 ratio and ApoA-1 showed statistically significant differences between groups. Multiple regression analysis demonstrated that p-tau 181 /Aβ42 had a significant odds ratio: OR = 1.42 (95% confidence interval [CI], 1.12–1.84), P = 0.006. Among the molecules investigated, intriguing correlations were observed that require further investigation. Our results suggest coexistent AD CSF biomarkers within the PD group notwithstanding that it was selected to minimize AD neuropathological lesions.
IC‐O2‐02: In dementia with Lewy bodies RBD is associated with reduced Alzheimer's disease pathology and hippocampal atrophy
Murray, Melissa E. , Petersen, Ronald C. , Parisi, Joseph E., Vemuri, Prashanthi , Ferman, Tanis J. , Dugger, Brittany N. , Jack, Clifford R. , Boeve, Bradley F. , Knopman, David S. , Dickson, Dennis W. , Kantarci, Kejal , Murray, Melissa E

Alzheimer's & Dementia | July 19, 2012 | Volume: 8 | Issue: 4S_Part_1 | Pages: No page available

10.1016/j.jalz.2012.05.024 Get It

IC‐P‐008: In dementia with Lewy bodies, rapid eye movement sleep behavior disorder is associated with reduced Alzheimer's disease pathology and hippocampal atrophy
Murray, Melissa E. , Petersen, Ronald C. , Parisi, Joseph E. , Vemuri, Prashanthi , Ferman, Tanis J. , Dugger, Brittany N. , Jack, Clifford R. , Boeve, Bradley F. , Knopman, David S. , Dickson, Dennis W. , Kantarci, Kejal , Murray, Melissa E

Alzheimer's & Dementia | July 19, 2012 | Volume: 8 | Issue: 4S_Part_1 | Pages: No page available

10.1016/j.jalz.2012.05.040 Get It

F2‐02‐06: Mixed Alzheimer's and Lewy Body Disease Pathology Patterns
Murray, Melissa E. , Dugger, Brittany N. , Dickson, Dennis W. , Murray, Melissa E

Alzheimer's & Dementia | October 26, 2010 | Volume: 6 | Issue: 4S_Part_19 | Pages: No page available

10.1016/j.jalz.2010.08.009 Get It

P1‐218: Mixed Alzheimer's and Lewy body disease pathology patterns
Murray, Melissa E. , Dugger, Brittany N. , Dickson, Dennis W.

Alzheimer's & Dementia | July 11, 2010 | Volume: 6 | Issue: 4S_Part_8 | Pages: No page available

10.1016/j.jalz.2010.05.769 Get It

Dopamine cell loss in the periaqueductal gray in multiple system atrophy and Lewy body dementia
Benarroch, Eduardo E. , Schmeichel, Ann M., Dugger, Brittany N. , Sandroni, Paola , Parisi, Joseph E., Low, Phillip A. , Dugger, Brittany N

Neurology | July 13, 2009 | Volume: 73 | Issue: 2 | Pages: 106-112

10.1212/wnl.0b013e3181ad53e7 Get It