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Ávila, Francisco R.

https://orcid.org/0000-0001-7856-1367

Mayo Clinic

Mayo Clinic

Citations 54

35. Human Adipose-derived Stem Cells Decrease Skin Damage in Mice After Scalp Irradiation: A Pilot Experiment
Maita, Karla C. , Garcia, John P., Eldaly, Abdullah S. , Serrano, Luiza Palmieri , Emam, Omar S. , Quiñones‐Hinojosa, Alfredo , Ávila, Francisco R. , Torres‐Guzman, Ricardo A. , Garcia, John P., Zubair, Abba C. , Forte, Antonio J. , Sarabia-Estrada, Rachel

Plastic and Reconstructive Surgery - Global Open | June 23, 2022 | Volume: 10 | Issue: 6S | Pages: 23-23

10.1097/01.gox.0000842468.52715.9c Get It

116. Hypoxic Culturing of Human Adipose-derived Stem Cells Enhances Cellular Proliferation and Angiogenesis
Garcia, John P., Maita, Karla C. , Eldaly, Abdullah S. , Rinker, Brian, Ávila, Francisco R. , Torres, Ricardo A., Zubair, Abba C. , Forte, Antonio J. , Sarabia-Estrada, Rachel

Plastic and Reconstructive Surgery - Global Open | June 23, 2022 | Volume: 10 | Issue: 6S | Pages: 76-76

10.1097/01.gox.0000842780.83877.19 Get It

Overall patient experience with a virtual hybrid hospital at home program
Maniaci, Michael J. , Garcia, John P. , Maita, Karla C. , Forte, Antonio J. , Torres-Guzman, Ricardo A, Garcia, John P , Forte, Antonio Jorge , Paulson, Margaret R. , Maniaci, Michael J , Torres‐Guzman, Ricardo A. , Ávila, Francisco R.

SAGE Open Medicine | April 23, 2022 | Volume: 10 | Issue: No issue available | Pages: No page available

10.1177/20503121221092589 Get It

Objectives: Traditional hospital at home models often have high patient experience scores. The purpose of this study is to look at the patient experience of a new virtual hybrid model of hospital at home called Advanced Care at Home. Methods: Patients in Mayo Clinic’s Advanced Care at Home program received a survey via email from 1 January–31 May 2021. Each survey consisted of 20 questions divided into 18 multiple-choice and two open-ended questions. Results: Ninety-nine surveys were sent and 41 partially or completely finished surveys were returned for a response rate of 41.4%. Patients responded positively, denoted by answering “strongly agree or somewhat agree,” with regard to the ability to reach the team right away 100% of the time, being kept informed 92% of the time, the command center responding promptly to their needs 95% of the time, the team providing comfort and support 98% of the time, feeling comfortable with interacting with their provider by phone or tablet 95% of the time, the ease of use from the equipment 97% of the time, the virtual and in-person staff working well together 98% of the time, the staff treating patients with courtesy and respect 100% of the time, and the ease of understanding the discharge process and feeling ready to leave the program 100% of the time. All providers received positive responses on listening ⩾88% of the time. Patients gave a top rating in likelihood to recommend the program 100% of the time. Conclusion: Overall, the Advanced Care at Home model of hospital at home was highly recommended by patients. Patients scored the program high on responsiveness, staff engagement and communication, ease of equipment use, and readiness for discharge, strengthening the overall confidence in this novel program.
A Virtual Hybrid Care Hotel Model Supports the Recovery of Post-procedural Patients with Mild to Severe Systemic Diseases
Ávila, Francisco R. , Torres‐Guzman, Ricardo A. , Maita, Karla C. , Garcia, John P. , Forte, Antonio J. , Matcha, Gautam , Pagán, Ricardo J. , Maniaci, Michael J. , Paulson, Margaret R. , Avila, Francisco R , Torres-Guzman, Ricardo A, Garcia, John P , Forte, Antonio Jorge , Matcha, Gautam V, Maniaci, Michael J , Torres, Ricardo A , Chadha, Ryan

The American Surgeon™ | April 14, 2022 | Volume: 89 | Issue: 6 | Pages: 2247-2253

10.1177/00031348221082271 Get It

Background Patients with mild to severe chronic systemic disease undergoing low-risk procedures are often hospitalized for observation. The Care Hotel is a novel virtual medicine hybrid model of care that offers patients a comfortable, out of hospital environment where they can receive both in-person and virtual care after a surgery or procedure. This study aimed to analyze if virtual hybrid post-procedure care in a hotel could be both conducted on and accepted by patients, even those with moderate to severe chronic diseases. Methods This retrospective cohort study was conducted between July 23, 2020 and June 4, 2021 at Mayo Clinic in Florida, a 306-bed community academic hospital. We collected the sex, age, race, ethnicity, acceptance rate, ASA score, and primary procedure of patients using the Care Hotel. Results Out of 392 patients, 272 (69.4%) opted for care in the program. Median patient age was 61.5 years, 59.56% were males, and 86.40% were white. We found that 50.37% had an ASA score of 2 and 43.4% had an ASA score of 3. Ten different surgical specialties were able to utilize the Care Hotel for care in 47 different procedure types. Urology had the most patients (n=70, 25.7%). Post-electrophysiologic procedures were the most common procedures (n=39, 14.3%). Conclusion Our virtual hybrid Care Hotel program was widely accepted by patients and could care for a multitude of post-operative procedures. Additionally, this novel program can care for patients with both mild and severe systemic diseases.
Vascularized Lymph Node Transfer for the Treatment of Posttraumatic Lower Extremity Lymphedema: A Preliminary Report
Ciudad, Pedro , Huayllani, María T. , Forte, Antonio J. , Escandón, Joseph M. , Manrique, Oscar J. , Boczar, Daniel , Ávila, Francisco R. , Escandón, Joseph M , Forte, Antonio Jorge , Chen, Hung‐Chi

Indian Journal of Plastic Surgery | March 1, 2022 | Volume: 55 | Issue: 01 | Pages: 097-101

10.1055/s-0041-1740520 Get It

Abstract Background Posttraumatic lymphedema develops more frequently than expected and reports on its management are scarce in the literature. We aimed to report the clinical outcomes of a case series of posttraumatic lymphedema patients treated with different vascularized lymph node transfers (VLNTs). Patients and Methods Five patients with secondary posttraumatic lower limb lymphedema treated with VLNT were included in this report. The groin-VLNT (n = 1), supraclavicular-VLNT (n = 2), and gastroepiploic-VLNT (n = 2) were implemented. The average flap area was 69.8 cm2. Patients underwent postoperative complex decompressive therapy for an average of 10.0 months. Results The average mean circumference reduction rate was 24.4% (range, 10.2–37.6%). Postsurgical reduction in the number of infection episodes per year was observed in all patients. The mean follow-up was 34.2 months. Conclusions VLNT is a promising surgical treatment for posttraumatic lymphedema patients. In our report, VLNT has demonstrated to reduce the volume and number of infections per year in posttraumatic lymphedema.
85-Year-Old Postsurgical Complex Patient Successfully Managed Remotely at the Novel Mayo Clinic’s Hospital at Home
Paulson, Margaret R. , Torres‐Guzman, Ricardo A. , Ávila, Francisco R. , Maita, Karla C. , Garcia, John P. , Eldaly, Abdullah S. , Serrano, Luiza Palmieri , Forte, Antonio J. , Thompson, Jonathan C. , Maniaci, Michael J. , Maita, Karla , Eldaly, Abdullah , Palmieri-Serrano, Luiza , Forte, Antonio Jorge , Torres, Ricardo A , Maniaci, Michael J , Avila, Francisco R , Garcia, John P , Paulson, Margaret R

Case Reports in Vascular Medicine | February 25, 2022 | Volume: 2022 | Issue: No issue available | Pages: 1-5

10.1155/2022/1439435 Get It

An 85-year-old male presented to the podiatry clinic following a 1st to 5th left toe amputation as a complication of severe peripheral arterial disease and nonhealing wound despite endovascular intervention with an angiogram. At the visit, cellulitis with gangrene of the surgical site was noted. The patient was admitted to the brick and mortar (BAM) hospital and taken to surgery for a transmetatarsal amputation of the left limb. In the immediate postoperative period, the incisional margins appeared dusky creating concern for flap viability. The medical team recommended a vascular bypass versus a below-knee amputation. However, given the age, comorbidities, and nutritional status, the family refused further surgical intervention. As such, Mayo Clinic’s home hospital program, Advanced Care at Home (ACH), was consulted for continued nonsurgical acute management at home. The patient was transferred to ACH and transported home three days after BAM admission to continue IV antibiotic therapy and wound care. Discharge from ACH occurred 11 days after admission to the BAM hospital. This case highlights the importance of developing health care alternatives to traditional hospitalization and demonstrates that ACH can manage highly complex, elder postoperative patients from the comfort of their homes.
Imaging Biomarkers for Diagnosis and Treatment Response in Patients with Lymphedema
Maita, Karla C. , Garcia, John P. , Torres‐Guzman, Ricardo A. , Ávila, Francisco R. , Kaplan, Jamie L. , Lu, Xiaona , Manrique, Oscar J. , Ciudad, Pedro , Forte, Antonio J. , Maita, Karla , Torres, Ricardo A , Forte, Antonio Jorge , Avila, Francisco R , Garcia, John P

Biomarkers in Medicine | February 18, 2022 | Volume: 16 | Issue: 4 | Pages: 303-316

10.2217/bmm-2021-0487 Get It

Simulation in Hand Surgery: A Literature Review
Saleem, Humza Y. , Kaplan, Jamie L. , Torres‐Guzman, Ricardo A. , Forte, Antonio J. , Ávila, Francisco R. , Forte, Antonio Jorge , Torres, Ricardo A

World Journal of Surgery | January 7, 2022 | Volume: 46 | Issue: 3 | Pages: 718-724

10.1007/s00268-021-06400-0 Get It

AbstractBackgroundDue to duty hour regulations, patient safety and inadequate operative time simulation have become a necessary part of surgical education and training in residency. Currently, there is no formal adoption of simulators for the use of surgical education or assessment in hand surgery. This literature review analyzes that the simulation techniques established thus far in hand surgery.MethodsA comprehensive literature search was performed on PubMed. Search results were filtered by title and abstract to isolate articles that were relevant to simulation in hand surgery. Articles that were nonspecific to the hand, non‐English and cadaveric were excluded. Additional articles were identified through references from the initial search.ResultsA total of 1192 articles were yielded from the initial query. After the application of the inclusion criteria, this was narrowed down to 28 articles. Another 8 additional articles were excluded as they did not pertain to the hand although the simulators could be adapted for hand surgery. A total of 20 articles were included in this study.ConclusionsSurgical simulation is a growing and essential field of surgical education. Simulators in hand surgery are limited and require further research and validation. Like other surgical subspecialties, hand surgery may benefit from the adoption of an official simulation curriculum for the assessment of residents and enhancement of technical skills.
Adipose-Derived Stem Cells Therapy for Radiation-Induced Skin Injury
Huayllani, María T. , Lu, Xiaona , Rinker, Brian, Moran, Steven L. , Quiñones‐Hinojosa, Alfredo , Forte, Antonio J. , Forte, Antonio Jorge , Ruiz-García, Henry , Boczar, Daniel , Ávila, Francisco R. , Sarabia-Estrada, Rachel

Annals of Plastic Surgery | November 1, 2021 | Volume: 87 | Issue: 6 | Pages: 639-649

10.1097/sap.0000000000003039 Get It

Background Radiation-induced skin injuries have been treated with different medical therapies and have shown diverse outcomes. We aim to evaluate the effect of adipose-derived stem cells (ADSCs) therapy on radiation-induced skin injury. Methods We performed a review by querying PubMed, Ovid MEDLINE, and EMBASE databases from inception to April 2020 following Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines. The MeSH terms “adipose-derived stem cells,” “wound healing,” “radiation,” and synonyms in combinations determined our search strategy. Experimental peer-reviewed articles describing the protocol and comparing the results with controls were included. Non-English studies were excluded. Results Our search recorded a total of 137 articles. Only 8 studies met our inclusion criteria and were included in this review. Five studies evaluated the use of ADSC alone, whereas the others evaluated the efficacy of ADSC seeded in scaffolds. Adipose-derived stem cell–based therapies, either alone or seeded in scaffolds, were shown to improve wound healing in most studies when compared with controls. Conclusions There is evidence supporting the positive benefits from ADSC-based therapies in radiation-induced skin injury. However, further studies are needed to standardize the method of ADSC extraction, radiation-induced skin injury experimental model, and increase the time of follow-up to evaluate the results accurately.
Application of Human Adipose-Derived Stem cells for Bone Regeneration of the Skull in Humans
Torres‐Guzman, Ricardo A. , Huayllani, María T. , Maita, Karla C. , Quiñones‐Hinojosa, Alfredo , Forte, Antonio J. , Forte, Antonio Jorge , Torres, Ricardo A , Ávila, Francisco R. , Zubair, Abba C. , Sarabia-Estrada, Rachel

Journal of Craniofacial Surgery | October 13, 2021 | Volume: 33 | Issue: 1 | Pages: 360-363

10.1097/scs.0000000000008114 Get It

Background: Archeological archives report cranioplasty as 1 of the oldest surgical procedures; however, it was not until the last century that true advances have been made. Alternative approaches are necessary to achieve optimal closure of the defect with fewer adverse effects. We aim to evaluate the use of human adipose-derived stem cells (hADSCs) alone or seeded in scaffolds as the main treatment for cranial bone defects and to assess human patient outcomes. Methods: A systematic review was performed by querying PubMed, Ovid MEDLINE, EMBASE, and Cumulative Index to Nursing and Allied Health Literature databases with the MeSH terms: “adipose-derived stem cells,” “cranial bone defect,” “stromal vascular factor,” “fat grafting,” as well as synonyms in combinations determined by our search strategy. We included human models that used hADSCs as primary therapy. We excluded studies in languages other than English. Results: One hundred ninety-four studies were identified after removal of duplicates. Four articles that used hADSCs as the main therapy to treat calvarial defects in humans were included. One article applied the cell therapy alone, and 3 used β-tricalcium phosphate granules as a scaffold to seed the hADSCs. Conclusions: Bone regeneration was reached in a short and intermediate period using autologous hADSCs in humans with no major adverse effects in all 4 articles included. A long-term follow-up study (6 years) exhibited late infections and reabsorption of the β-tricalcium phosphate scaffold seeded with hADSCs.