Mayo Clinic - AuthorCitation

The bivariate distribution of amyloid-β and tau: relationship with established neurocognitive clinical syndromes

Jack, Clifford R. , Wiste, Heather J. , Botha, Hugo , Weigand, Stephen D. , Therneau, Terry M. , Graff‐Radford, Jonathan , Ferman, Tanis J. , Boeve, Bradley F. , Kantarci, Kejal , Lowe, Val J. , Vemuri, Prashanthi , Fields, Julie A. , Senjem, Matthew L. , Gunter, Jeffrey L. , Petersen, Ronald C. , Jack, Clifford R , Boeve, Brad , Vemuri, Prashanthi , Senjem, Matthew L , Kantarci, Kejal , Botha, Hugo , Ferman, Tanis J , Knopman, David S. , Jones, David T. , Mielke, Michelle M. , Machulda, Mary M. , Schwarz, Christopher G.

Brain | August 28, 2019 | Volume: 142 | Issue: 10 | Pages: 3230-3242

See Gordon and Tijms (doi:10.1093/brain/awz278) for a scientific commentary on this article. Jack et al. examine relationships between the bivariate distribution of β-amyloid and tau on PET and established neurocognitive clinical syndromes. Amyloidosis appears to be required for high levels of 3R/4R tau deposition. Whereas abnormal amyloid PET is compatible with normal cognition, highly abnormal tau PET is not.

Prevalence of Biologically vs Clinically Defined Alzheimer Spectrum Entities Using the National Institute on Aging–Alzheimer’s Association Research Framework

Jack, Clifford R. , Therneau, Terry M. , Weigand, Stephen D. , Wiste, Heather J. , Vemuri, Prashanthi , Lowe, Val J. , Roberts, Rosebud O., Graff‐Radford, Jonathan , Gunter, Jeffrey L. , Senjem, Matthew L. , Rocca, Walter A. , Petersen, Ronald C. , Jack, Clifford R , Vemuri, Prashanthi , Senjem, Matthew L , Knopman, David S. , Mielke, Michelle M. , Machulda, Mary M. , Jones, David T. , Schwarz, Christopher G.

JAMA Neurology | July 15, 2019 | Volume: 76 | Issue: 10 | Pages: 1174

10.1001/jamaneurol.2019.1971

Associations of Amyloid, Tau, and Neurodegeneration Biomarker Profiles With Rates of Memory Decline Among Individuals Without Dementia

Jack, Clifford R. , Wiste, Heather J. , Therneau, Terry M. , Weigand, Stephen D. , Lowe, Val J. , Vemuri, Prashanthi , Gunter, Jeffrey L. , Senjem, Matthew L. , Graff‐Radford, Jonathan , Roberts, Rosebud O., Rocca, Walter A. , Petersen, Ronald C. , Jack, Clifford R , Vemuri, Prashanthi , Senjem, Matthew L , Knopman, David S. , Mielke, Michelle M. , Machulda, Mary M. , Schwarz, Christopher G. , Jones, David T.

JAMA | June 18, 2019 | Volume: 321 | Issue: 23 | Pages: 2316

10.1001/jama.2019.7437

Cross-sectional associations of tau-PET signal with cognition in cognitively unimpaired adults

Lowe, Val J. , Bruinsma, Tyler J. , Wiste, Heather J. , Min, Hoon‐Ki , Weigand, Stephen D. , Fang, Ping , Senjem, Matthew L. , Therneau, Terry M. , Josephs, Keith A. , Pandey, Mukesh K. , Murray, Melissa E. , Kantarci, Kejal , Vemuri, Prashanthi , Graff‐Radford, Jonathan , Roberts, Rosebud O., Petersen, Ronald C. , Jack, Clifford R. , Min, Hoon-Ki Paul , Jack, Clifford R , Vemuri, Prashanthi , Senjem, Matthew L , Kantarci, Kejal , Murray, Melissa E , Pandey, Mukesh K , Boeve, Bradley F. , Jones, David T. , Schwarz, Christopher G. , Machulda, Mary M. , Mielke, Michelle M. , Knopman, David S.

Neurology | May 31, 2019 | Volume: 93 | Issue: 1 | Pages: No page available

10.1212/wnl.0000000000007728

O2‐04‐05: CSF BIOMARKERS IN THE GENERAL POPULATION: ASSOCIATIONS WITH DEMOGRAPHICS AND APOE GENOTYPE

Wiste, Heather J. , Weigand, Stephen D. , Eichenlaub, Udo, Batrla‐Utermann, Richard, Petersen, Ronald C. , Harten, Argonde C. van , Mielke, Michelle M. , Kremers, Walter K. , Knopman, David S. , Jack, Clifford R.

Alzheimer's & Dementia | October 22, 2018 | Volume: 14 | Issue: 7S_Part_11 | Pages: No page available

10.1016/j.jalz.2018.06.2661

IC‐P‐028: VARIABILITY IN PDMN CONNECTIVITY AND RELATIVE HUBNESS IN COGNITIVELY NORMAL INDIVIDUALS PREDICT AMYLOID AND TAU DEPOSITION PATTERNS IN TYPICAL ALZHEIMER'S DISEASE

Graff‐Radford, Jonathan , Lowe, Val J. , Przybelski, Scott A. , Wiste, Heather J. , Gunter, Jeffrey L. , Petersen, Ronald C. , Botha, Hugo , Senjem, Matthew L. , Kantarci, Kejal , Boeve, Bradley F. , Knopman, David S. , Jack, Clifford R. , Jones, David T.

Alzheimer's & Dementia | October 22, 2018 | Volume: 14 | Issue: 7S_Part_1 | Pages: No page available

10.1016/j.jalz.2018.06.2092

P3‐443: ACCELERATED FAILURE TIME AS A MODEL FOR AMYLOID AND TAU ACCUMULATION

Therneau, Terry M. , Weigand, Stephen D. , Wiste, Heather J. , Lowe, Val J. , Roberts, Rosebud O., Petersen, Ronald C. , Vemuri, Prashanthi , Mielke, Michelle M. , Knopman, David S. , Jack, Clifford R.

Alzheimer's & Dementia | October 22, 2018 | Volume: 14 | Issue: 7S_Part_24 | Pages: No page available

10.1016/j.jalz.2018.06.1806

P1‐442: VARIABILITY IN PDMN CONNECTIVITY AND RELATIVE HUBNESS IN COGNITIVELY NORMAL INDIVIDUALS PREDICT AMYLOID AND TAU DEPOSITION PATTERNS IN TYPICAL ALZHEIMER'S DISEASE

Graff‐Radford, Jonathan , Lowe, Val J. , Przybelski, Scott A. , Wiste, Heather J. , Gunter, Jeffrey L. , Petersen, Ronald C. , Botha, Hugo , Senjem, Matthew L. , Kantarci, Kejal , Boeve, Bradley F. , Knopman, David S. , Jack, Clifford R. , Jones, David T.

Alzheimer's & Dementia | October 22, 2018 | Volume: 14 | Issue: 7S_Part_8 | Pages: No page available

10.1016/j.jalz.2018.06.451

Longitudinal tau PET in ageing and Alzheimer’s disease

Jack, Clifford R. , Wiste, Heather J. , Lowe, Val J. , Senjem, Matthew L. , Vemuri, Prashanthi , Weigand, Stephen D. , Therneau, Terry M. , Knopman, D. S., Gunter, Jeffrey L. , Graff‐Radford, Jonathan , Kantarci, Kejal , Roberts, Rosebud O., Petersen, Ronald C. , Knopman, Dave S, Jack, Clifford R , Vemuri, Prashanthi , Senjem, Matthew L , Kantarci, Kejal , Schwarz, Christopher G. , Jones, David T. , Mielke, Michelle M. , Machulda, Mary M.

Brain | February 22, 2018 | Volume: 141 | Issue: 5 | Pages: 1517-1528

10.1093/brain/awy059

Tau-negative amnestic dementia masquerading as Alzheimer disease dementia

Botha, Hugo , Mantyh, William G. , Graff‐Radford, Jonathan , Przybelski, Scott A. , Wiste, Heather J. , Senjem, Matthew L. , Parisi, Joseph E., Petersen, Ronald C. , Murray, Melissa E. , Lowe, Val J. , Jack, Clifford R. , Jack, Clifford R , Senjem, Matthew L , Botha, Hugo , Murray, Melissa E , Machulda, Mary M. , Boeve, Bradley F. , Knopman, David S. , Jones, David T.

Neurology | February 7, 2018 | Volume: 90 | Issue: 11 | Pages: No page available

10.1212/wnl.0000000000005124

Wiste, Heather J.

Citations 135

The bivariate distribution of amyloid-β and tau: relationship with established neurocognitive clinical syndromes

Prevalence of Biologically vs Clinically Defined Alzheimer Spectrum Entities Using the National Institute on Aging–Alzheimer’s Association Research Framework

Associations of Amyloid, Tau, and Neurodegeneration Biomarker Profiles With Rates of Memory Decline Among Individuals Without Dementia

Cross-sectional associations of tau-PET signal with cognition in cognitively unimpaired adults

O2‐04‐05: CSF BIOMARKERS IN THE GENERAL POPULATION: ASSOCIATIONS WITH DEMOGRAPHICS AND APOE GENOTYPE

Wiste, Heather J. , Weigand, Stephen D. , Eichenlaub, Udo, Batrla‐Utermann, Richard, Petersen, Ronald C. , Harten, Argonde C. van , Mielke, Michelle M. , Kremers, Walter K. , Knopman, David S. , Jack, Clifford R.

IC‐P‐028: VARIABILITY IN PDMN CONNECTIVITY AND RELATIVE HUBNESS IN COGNITIVELY NORMAL INDIVIDUALS PREDICT AMYLOID AND TAU DEPOSITION PATTERNS IN TYPICAL ALZHEIMER'S DISEASE

Graff‐Radford, Jonathan , Lowe, Val J. , Przybelski, Scott A. , Wiste, Heather J. , Gunter, Jeffrey L. , Petersen, Ronald C. , Botha, Hugo , Senjem, Matthew L. , Kantarci, Kejal , Boeve, Bradley F. , Knopman, David S. , Jack, Clifford R. , Jones, David T.

P3‐443: ACCELERATED FAILURE TIME AS A MODEL FOR AMYLOID AND TAU ACCUMULATION

Therneau, Terry M. , Weigand, Stephen D. , Wiste, Heather J. , Lowe, Val J. , Roberts, Rosebud O., Petersen, Ronald C. , Vemuri, Prashanthi , Mielke, Michelle M. , Knopman, David S. , Jack, Clifford R.

P1‐442: VARIABILITY IN PDMN CONNECTIVITY AND RELATIVE HUBNESS IN COGNITIVELY NORMAL INDIVIDUALS PREDICT AMYLOID AND TAU DEPOSITION PATTERNS IN TYPICAL ALZHEIMER'S DISEASE

Graff‐Radford, Jonathan , Lowe, Val J. , Przybelski, Scott A. , Wiste, Heather J. , Gunter, Jeffrey L. , Petersen, Ronald C. , Botha, Hugo , Senjem, Matthew L. , Kantarci, Kejal , Boeve, Bradley F. , Knopman, David S. , Jack, Clifford R. , Jones, David T.

Longitudinal tau PET in ageing and Alzheimer’s disease

Tau-negative amnestic dementia masquerading as Alzheimer disease dementia