Citations 2
Serum triamcinolone levels during intensive, inpatient wet‐dressing therapy
Mirza, Shireen, Wentworth, Ashley B., Harvey, Jamison A. , Bridges, Alina G. , Camilleri, Michael , McEvoy, M., Sartori‐Valinotti, Julio C. , Wetter, David A. , Davis, Mark D. P. , Sartori-Valinotti, J C , Mirza, S. A., el‐Azhary, Rokea A. , Davis, Mark D.P.
Clinical and Experimental Dermatology | May 15, 2020 | Volume: 45 | Issue: 5 | Pages: 549-554
Treatment of acne with spironolactone: a retrospective review of 395 adult patients at Mayo Clinic, 2007–2017
Roberts, Erin , Nowsheen, Somaira , Davis, Mark D. P. , McEvoy, M., Newman, Catherine C., Sartori‐Valinotti, Julio C. , Sciallis, Gabriel F., Torgerson, Rochelle R. , Wetter, David A. , Nowsheen, Somaira , Davis, Mark D.P.
Journal of the European Academy of Dermatology and Venereology | February 20, 2020 | Volume: 34 | Issue: 9 | Pages: 2106-2110
AbstractBackgroundFew large studies have assessed spironolactone treatment of adult female acne.ObjectivesTo explore the role of spironolactone in the treatment of adult female acne.MethodsWe performed a retrospective case series assessing the efficacy of spironolactone treatment of a cohort of women evaluated at Mayo Clinic in Rochester, Minnesota, from 2007 through 2017.ResultsIn total, 395 patients (median age, 32 years) received a median spironolactone dose of 100 mg daily. Approximately two‐thirds of patients (66.1%) had a complete response; 85.1% had a complete response or a partial response greater than 50%. Median times to initial response and maximum response were 3 and 5 months. Efficacy was observed across all severity subtypes of acne, including those with papulopustular and nodulocystic acne. Patients received long‐term treatment with spironolactone (median duration, 13 months) and had few adverse effects.ConclusionsSpironolactone is a safe and effective treatment of acne for women.