Citations 1
Multifocal Urinary Bladder Paragangliomas With Negative 68Ga-DOTATATE Uptake and Positive 123I-MIBG Uptake
Parra, Laura, Swanson, Scott K., Salomao, Marcela , Yang, Ming , Salomao, Marcela A, Salomao, Marcela
Clinical Nuclear Medicine | November 12, 2019 | Volume: 45 | Issue: 3 | Pages: e156-e157
Abstract We report a case of an adult male patient with multifocal urinary bladder paragangliomas, which were negative on 68Ga-DOTATATE PET/CT scan, but positive on 123I-MIBG SPECT/CT scan. While the 68Ga-DOTA analog PET/CT exhibits superior performance in diagnosis and staging of pheochromocytoma and paraganglioma, our case demonstrates negative somatostatin receptor expression in this rare entity and indicates that 123I-MIBG SPECT/CT still plays a vital role in characterization of bladder paraganglioma.