Citations 1
Engineered nanoparticles for systemic siRNA delivery to malignant brain tumours
Karlsson, Johan , Rui, Yuan , Kozielski, Kristen , Placone, Amanda L., Choi, Olivia, Tzeng, Stephany Y. , Keyes, Jamal J., Bogorad, Max I. , Guerrero‐Cazares, Hugo , Quiñones‐Hinojosa, Alfredo , Green, Jordan J. , Guerrero-Cázares, Hugo, Searson, Peter C , Green, Jordan J , Guerrero-Cazares, Hugo , Tzeng, Stephany Y , Choi, Olivia, Kim, Jayoung , Gabrielson, Kathleen L.
Nanoscale | October 3, 2019 | Volume: 11 | Issue: 42 | Pages: 20045-20057
Bioreducible nanoparticles were engineered for safe and effective systemic siRNA delivery, including crossing the blood–brain barrier to achieve in vivo gene silencing in an orthotopic glioblastoma mouse model.