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Muthupillai, Raja

https://orcid.org/0000-0001-5041-2562

Mayo Clinic

Mayo Clinic

Citations 1

Magnetic Resonance Elastography by Direct Visualization of Propagating Acoustic Strain Waves
Muthupillai, Raja , Lomas, David J. , Rossman, Phillip J. , Greenleaf, James F. , Manduca, Armando , Ehman, Richard L.

Science | October 27, 2006 | Volume: 269 | Issue: 5232 | Pages: 1854-1857

10.1126/science.7569924 Get It

A nuclear magnetic resonance imaging (MRI) method is presented for quantitatively mapping the physical response of a material to harmonic mechanical excitation. The resulting images allow calculation of regional mechanical properties. Measurements of shear modulus obtained with the MRI technique in gel materials correlate with independent measurements of static shear modulus. The results indicate that displacement patterns corresponding to cyclic displacements smaller than 200 nanometers can be measured. The findings suggest the feasibility of a medical imaging technique for delineating elasticity and other mechanical properties of tissue.