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Gaumann, Dorothee M.

Mayo Clinic

Mayo Clinic

Citations 4

Intrathecal somatostatin in rats. antinociception only in the presence of toxic effects
Gaumann, Dorothee M., Yaksh, Tony L.

Regional Anesthesia: The Journal of Neural Blockade in Obstetrics, Surgery, & Pain Control | October 11, 2025 | Volume: 13 | Issue: Suppl 1 | Pages: 49-49

10.1136/rapm-00115550-198813011-00049 Get It

Continuous Axillary Block for Postoperative Pain Management
Gaumann, Dorothee M., Lennon, Robert L., Wedel, Denise J.

Regional Anesthesia: The Journal of Neural Blockade in Obstetrics, Surgery, & Pain Control | September 4, 2025 | Volume: 13 | Issue: 2 | Pages: 77-82

10.1136/rapm-00115550-198813020-00007 Get It

The current study was conducted to establish a reliable method for the placement of a long (>5 cm) catheter in the axillary neurovascular sheath, and to assess the effect of proximal catheter position on postoperative pain management by continuous bupivacaine infusion. In 20 patients scheduled for upper extremity surgery, a Portex® epidural catheter was advanced a mean distance of 12 cm in the axillary neurovascular sheath and its correct position verified by onset of upper extremity anesthesia and x-ray examination. After operation a continuous infusion of bupivacaine 0.125% was initiated through this catheter. Excellent pain relief (score of 0-1 as evaluated on a visual analogue scale of 0 to 10), and sympathetic blockade was achieved in all patients with an average rate of bupivacaine administration of 7 ml/hr. Additionally administered systemic narcotics were in a mean range of 3-10 mg of morphine/day. Catheters remained in place for an average of 3.7 days. Catheter tips cultured on removal of the catheter (n = 11) yielded negative cultures in eight cases (placement 3.6 ± 0.6 days), and positive cultures in three cases (placement 8.6 ± 2.2 days, mean ± SE). No signs of local or systemic infection were noted in any patient and no specific antibiotic therapy was initiated. This technique is recommended for postoperative analgesia in selected patients. In this study there was a low risk of catheter displacement and no evidence of local anesthetic toxicity. Limiting the duration of continuous axillary catheter infusion to 4 days may minimize the risk of infection.
Intrathecal somatostatin causes severe hindleg dysfunction in cats and is devoid of analgesic effects
Gaumann, Dorothee M., Yaksh, T. L., Rodriquez, Manuel, Post, C. P.

Regional Anesthesia: The Journal of Neural Blockade in Obstetrics, Surgery, & Pain Control | September 4, 2025 | Volume: 13 | Issue: Suppl 1 | Pages: 44-44

10.1136/rapm-00115550-198813011-00044 Get It

μ-,δ- AND κ-RECEPTOR AGONISTS PRESERVE THE ADRENAL MEDULLARY RESPONSE EVOKED BY SEVERE HEMORRHAGE
Gaumann, Dorothee M., Yaksh, T. L., Tyce, G. M., Lucas, Darlene L.

Anesthesiology | October 10, 2006 | Volume: 67 | Issue: 3 | Pages: A677-A677

10.1097/00000542-198709001-00677 Get It