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30 citation(s) found for "Reece, Edward".

Precision-Oriented Reconstruction After Spinal Sarcoma Resection: Integrating Surgical Strategy, Biologic Risk, and Emerging Technologies
Carcione, Tanner, Callas, Bradley, Thiara, Jack, Jungbauer, W. Nicholas , Jeger, Jonathan L. , Reece, Edward, Jungbauer, Walter N , Jeger, Jonathan L

Mayo Clinic

Cancers | May 11, 2026 | Volume: 18 | Issue: 10 | Pages: 1555

10.3390/cancers18101555 | PMID 42192916 Get It

Background/Objectives: Primary spinal sarcomas, encompassing both bone and soft tissue histotypes, demand individualized reconstruction due to heterogeneous tumor biology, anatomic complexity, and host environments compromised by radiation, systemic therapy, or prior surgery. This narrative review reframes post-resection spinal reconstruction through a precision-medicine lens. Methods: A structured literature review was performed using PubMed and Scopus, targeting articles published between 2000 and 2026. Searches encompassed spinal sarcoma reconstruction, radiation and fusion, biologic reconstruction, and emerging technologies. Results: Tumor grade, radiation exposure, and systemic therapy timing emerge as multiplicative determinants of reconstructive environment quality, with drug-class-specific perioperative effects warranting stratified management. Vascularized bone grafts achieve reliable fusion in compromised hosts where avascular constructs fail. A precision-oriented reconstructive ladder is proposed as a conceptual, hypothesis-generating framework to guide strategy selection. Hybrid PSI-VBG constructs may further expand reconstructive possibilities. The evidence base remains largely composed of small, retrospective series. Conclusions: Individualized strategies anchored in tumor biology and host environment are the cornerstone of durable spinal sarcoma reconstructions. The proposed framework requires prospective, multi-institutional validation. Standardized outcome definitions, prospective registries, and histotype-stratified analyses are needed to advance the field.
The Importance of Plastic Surgery in Multidisciplinary Teams: A Systematic Review and Meta-analysis of Comparative Studies
Elemosho, Abdulaziz , Kardan, Ramiz, Reece, Edward M., GORDON, C, Heniford, B. Todd, Janis, Jeffrey E., Janis, Jeffrey E. , Souza, Jason M. , Heniford, B. Todd

Mayo Clinic

Plastic and Reconstructive Surgery - Global Open | April 21, 2026 | Volume: 14 | Issue: 4 | Pages: e7631

10.1097/gox.0000000000007631 | PMID 42021977 Get It

Background: Multidisciplinary team (MDT) care facilitates coordinated expertise that leads to improved patient safety and outcomes. Yet, no prior study has quantified reported benefits from plastic surgery–inclusive MDTs across several procedures. We thereby hypothesized that plastic surgery–inclusive MDTs would lead to better surgical outcomes following cranioplasty, spine surgery, abdominoperineal resection, abdominal wall reconstruction, and extremity reconstruction, compared with the primary specialties acting alone. Methods: Following Preferred Reporting Items for Systematic Reviews and Meta-analysis guidelines, we searched PubMed, Embase, Scopus, and Web of Science for comparative studies comparing outcomes of care provided by plastic surgery–inclusive MDT and non–plastic surgery–inclusive MDT. Results: Thirty studies with a total of 9614 patients were included. Plastic surgery–inclusive MDT care was associated with reduced odds of wound complications in abdominoperineal resection (odds ratio [OR] = 0.65; 95% confidence interval [CI], 0.47–0.90) and spine procedures (OR = 0.57; 95% CI, 0.33–0.97). In addition, plastic surgery–inclusive MDT care for extremity reconstruction and abdominal wall reconstruction was associated with lower odds of wound complications ([OR = 0.24; 95% CI, 0.12–0.46] [OR = 0.33; 95% CI, 0.12–0.90]), reoperation ([OR = 0.13; 95% CI, 0.04–0.49] [OR = 0.26; 95% CI, 0.03–2.39]), and shorter length of stay (mean difference, −19.5 and −0.62, respectively). Conclusions: Plastic surgery–inclusive MDT care significantly reduces wound complication and reoperation rates across complex surgical procedures. These findings support the formal integration of plastic surgeons within MDTs to improve patient outcomes and surgical safety.
Breast Implants and Pectus Deformity Repair: A Retrospective Study and Clinical Recommendations
Khedr, Ahmed E. , Zeineddine, Rawan M. , Odeh, Nour B., Senjab, Abdulrahman , Farina, Juan M, Rebecca, Alanna M. , Casey, W. B., Rhee, Dan H, Reece, Edward M., Jaroszewski, Dawn E. , Farina, Juan M.

Mayo Clinic

Journal of the American College of Surgeons | February 24, 2026 | Volume: 243 | Issue: 1 | Pages: 130-140

10.1097/xcs.0000000000001882 | PMID 41733249 Get It

BACKGROUND: Pectus deformities are common chest wall abnormalities, with surgical correction recommended for severe cases. Female patients undergoing repair may have a history of breast implants or seek concurrent augmentation. This retrospective study examines clinical implications of pectus repair in patients with breast implants and provides recommendations. STUDY DESIGN: A retrospective review of female patients undergoing pectus repair at Mayo Clinic Arizona (January 1, 2010 to February 1, 2025) was conducted. Outcomes and complications were analyzed in patients with and without breast implants. RESULTS: In total, 456 female patients were included (447 excavatum, 7 arcuatum, and 2 carinatum; median age 32.7). Most patients (78.5%) underwent primary minimally invasive repairs (MIRPE); 6.6% underwent primary hybrid MIRPE, 5.5% underwent redo MIRPE, and 9.4% underwent primary redo open and complex reconstructions. In total, 104 patients (22.8%) had a history of breast implants, with 68 patients having breast implant-related procedures at the time of pectus surgery. At 12 months, the cumulative incidence of infection was significantly higher in patients with implants present at the time of pectus repair than in those without (8.8% vs 1.8%; log rank, p = 0.0015). A 4.9-fold increase in overall infection was seen in patients with indwelling or placed implants during pectus surgery. Deep infections were significantly more common in patients with implants (4.4%) than without (1.0%; p = 0.035). Similarly, superficial infections were more frequent in patients with implants (4.4%) than without (0.8%; p = 0.016). At 30 days, patients with implants had higher rates of infection (p = 0.032), pneumothorax (p = 0.008), and hematoma (p = 0.027), with no significant differences in other complications. CONCLUSIONS: Breast implants at the time of pectus repair were associated with increased risk of postoperative infection, pneumothorax, and hematoma. Removal of implants before pectus repair is recommended with delayed replacement, if desired.
Department or Division: Does it Matter for Plastic Surgery Programs?
Ruta, Michael R , Plonkowski, Alexander, Mahanti, Hannah J., Bernard, Robert W. , Reece, Edward M., Jungbauer, Walter N , Plonkowski, Alexander T. , Mahanti, Hannah

Mayo Clinic

Journal of Craniofacial Surgery | February 18, 2026 | Volume: 37 | Issue: 6 | Pages: 1541-1544

10.1097/scs.0000000000012463 | PMID 41705705 Get It

As plastic surgery has grown, leaders within the field have advocated transforming plastic surgery divisions into independent departments. This shift raises critical questions regarding departmental identity, resource allocation, and potential administrative conflicts. The purpose of this study was to explore the potential implications of these institutional hierarchies from the perspective of plastic surgery program chairs. An anonymous online survey was distributed to chairs of accredited plastic surgery programs. Thirty-five of 103 (34.0%) individuals responded to the online questionnaire. Twenty-eight of 33 (84.8%) programs were classified as divisions of surgery, whereas 5 of 33 (15.2%) were independent departments. Nine of 28 (32.1%) respondents believed their division had lost patients to other surgical specialties because their program was not an independent department. Eighteen of 33 (54.5%) respondents believed that plastic surgery is negatively impacted when institutional programs are not independent departments. Respondents who indicated losing patients to other specialties, compared with those who did not, were 22.4 times more likely to be critical of institutional hierarchies ( P =0.004). Respondents from independent departments were 12.6 times more likely to also express a negative view ( P =0.049). Our findings provide a nuanced understanding of the institutional structures within plastic surgery programs. The extent to which institutional hierarchies negatively impact plastic surgery remains unclear. The significant association between patient loss and negative perceptions implies that direct clinical or financial repercussions strongly shape opinions. Moreover, chairs from independent departments may be more critical of institutional hierarchies because they have a deeper appreciation for the advantages that come with departmental status.
Biologic Reconstruction in the Compromised Spine: A Review of Vascularized Bone Grafts to Mitigate Complications After Sarcoma Resection
Carcione, Tanner, Jeger, Jonathan L. , Jungbauer, W. Nicholas , Meyer, Jenna, Reece, Edward, Jungbauer, Walter N , Carcione, Tanner, Jeger, Jonathan L , Meyer, Jenna, Reece, Edward

Mayo Clinic

Complications | December 12, 2025 | Volume: 2 | Issue: 4 | Pages: 30

10.3390/complications2040030 Get It

Spinal sarcomas are rare, aggressive tumors requiring wide resection that creates large, challenging defects. Conventional reconstruction using allografts or metallic implants is prone to failure in compromised settings like irradiated or infected tissue. This narrative review synthesizes the literature on biologic reconstruction strategies, focusing on vascularized bone grafts (VBGs) and the ‘spinoplastic’ reconstruction approach, to provide a clinical framework for their application. We performed a narrative literature review using PubMed and Scopus to synthesize clinical studies describing biologic spinal reconstruction in compromised host beds. The main findings show that pedicled VBGs (e.g., rib, iliac crest) and free VBGs (e.g., fibula) function as living structural components. ‘Spinoplastic’ reconstruction leverages these grafts to promote biologic fusion, with clinical series reporting high union rates, even in irradiated or revision settings, offering a durable alternative to avascular constructs. Biologic reconstruction using VBGs is a critical strategy for achieving durable spinal stability in these challenging scenarios, and future directions point toward hybrid strategies combining 3D-printed implants with the biologic power of VBGs.
Lymphovenous Anastomosis and Vascularized Lymph Node Transfer Reduce Long-term Cellulitis Events in Patients With Secondary Lymphedema
Solomon, Santana, Verhey, Erik M., Jeger, Jonathan L. , Rhee, Daniel H. , Rebecca, Alanna M. , Saint-Cyr, Michel, Reece, Edward M., Casey, William J., Jungbauer, Walter N , Solomon, Santana, Jeger, Jonathan L , Chang, Yu‐Hui

Mayo Clinic

Annals of Plastic Surgery | October 10, 2025 | Volume: 95 | Issue: 5 | Pages: 522-530

10.1097/sap.0000000000004508 | PMID 41071856 Get It

Background Secondary lymphedema frequently occurs following surgery, malignancy, trauma, or radiation and is characterized by limb swelling, discomfort, and recurrent infections. Two advanced supermicrosurgical techniques—lymphovenous anastomosis (LVA) and vascularized lymph node transfer (VLNT)—have recently gained popularity as treatment options. However, long-term outcome data for these procedures remain limited. This systematic review and meta-analysis aim to evaluate the long-term efficacy of LVA and VLNT in patients with secondary lymphedema followed for more than 2 years postoperatively, focusing on outcomes such as cellulitis rates and limb circumference. Methods This study followed the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines. Inclusion criteria encompassed studies involving adult patients with secondary lymphedema treated with LVA or VLNT and with at least 24 months of follow-up. The primary outcomes were annual cellulitis incidence and limb circumference change, analyzed separately for upper and lower extremities. Meta-analysis was conducted using R version 4.3.1. Pooled effect sizes were estimated using random-effects models. Subgroup and sensitivity analyses were also performed. Results A total of 23 studies met the inclusion criteria, covering 648 limbs treated with either LVA (n = 216) or VLNT (n = 432). The weighted average patient age was 56.3 years, and the cohort was predominantly female (99.9%). For LVA, the pooled mean reduction in annual cellulitis events was −1.13 (95% confidence interval [CI], −1.70 to −0.57) for upper extremities and −1.32 (95% CI, −2.08 to −0.55) for lower extremities. VLNT yielded greater reductions in cellulitis, with pooled mean differences of −2.43 (95% CI, −3.36 to −1.50) and −1.38 (95% CI, −2.11 to −0.65) for upper and lower limbs, respectively. Additionally, VLNT reduced limb circumference by 42.7% (95% CI, 36.7–49.7) in upper extremities and 21.98% (95% CI, 19.8–24.4) in lower extremities. Conclusion LVA and VLNT both result in durable, long-term improvements in cellulitis rates, and VLNT was shown to reduce limb circumference. Given the significant impact on patient quality of life, these interventions should remain integral to the treatment algorithm for secondary lymphedema.
Spinoplastic Surgery: A Review of Techniques, Indications, and Optimal Patient Selection
Vernik, Daniel M. , Payne, Camryn, Sinha, Krishna , Martinez, Casey , Jeger, Jonathan L. , Bohl, Michael A. , Ropper, Alexander E., Winocour, Sebastian, Reece, Edward M., Vernik, Daniel , Jungbauer, Walter Nicholas, Jeger, Jonathan L , Payne, Camryn, Sinha, Krishna , Jungbauer, Walter N

Mayo Clinic

Brain Sciences | July 1, 2025 | Volume: 15 | Issue: 7 | Pages: 705

10.3390/brainsci15070705 | PMID 40722298 Get It

Background/Objectives: Spinoplastic surgery is an emerging multidisciplinary field developed to address and reduce the complication of pseudoarthrosis following complex spinal reconstructions. While the number of spinal fusion procedures continues to rise every year, fusion failure rates remain as high as 40%. Although pseudoarthrosis may not always manifest clinically, it remains a leading cause of persistent pain and need for subsequent revision surgeries. The multidisciplinary collaboration between spine and plastic surgeons in spinoplastic surgery has therefore emerged as a proactive strategy aimed at preventing complications, particularly in patients identified as high-risk for pseudoarthrosis. As the patient population expands and spinoplastic surgery continues to evolve, refining patient selection criteria becomes essential for achieving optimal surgical outcomes. This review aims to provide a comprehensive overview of recent advancements in spinoplastic surgery, highlighting current indications, surgical techniques, recent case reports, and strategies for identifying suitable candidates. Methods: We performed a narrative review of English language literature through April 2025. Spinoplastic case reports and case series published within the last 20 years were included in the review. Results: Indications for use of a spinoplastic approach clustered into prior fusion failure, extensive oncologic resection, severe spinal deformity, procedures requiring extensive spinal involvement, and/or patients at risk for impaired bone healing. Succesful radiographic union and improvement of symptoms were widely reported across all 9 case reports/series. Conclusions: Although evidence is presently limited, spinoplastic surgery appears to achieve high bone graft fusion rates with acceptable morbidity and functional improvement in a carefully selected group of high-risk spinal reconstruction patients. Still, larger prospective studies are warranted to refine patient selection and validate functional benefit.
Continuous Performance Improvement: Know Your Data
Aiello, Christopher, Smith, Isabelle T. , Reece, Edward M., Tanna, Neil

Mayo Clinic

FACE | June 16, 2025 | Volume: 6 | Issue: 3 | Pages: 526-528

10.1177/27325016251351164 Get It

Impact of Judicious Fluid Administration in the Setting of Abdominally Based Free Flaps
Kandi, Lyndsay A. , Spronsen, Nicole Van , Jungbauer, W. Nicholas , Sexton, Jaime, Movtchan, Nellie V., Reece, Edward, Rebecca, Alanna M. , Casey, William J., Movtchan, Nellie, Jungbauer, Walter N , Sexton, Jaime, Chang, Yu‐Hui

Mayo Clinic

Journal of Reconstructive Microsurgery | May 20, 2025 | Volume: 42 | Issue: 03 | Pages: 214-221

10.1055/a-2616-4598 | PMID 40393684 Get It

Abstract Abdominally based free flaps are commonly utilized in the context of breast reconstruction. Historically, postoperative care of these patients involved liberal amounts of intravenous fluid administration; however, overadministration of fluids puts patients at risk of developing flap edema via fluid shifts, electrolyte imbalances, wound dehiscence, and other sequelae. The purpose of this study is to assess fluid administration trends in this cohort at the authors' institution and assess its impact on patient outcomes. A retrospective review was performed on patients who underwent free-flap breast reconstruction. Patient demographics and hospitalization data were collected, and type of abdominal flap and reconstruction timing was noted. Perioperative fluid administration volumes were tracked, and primary outcomes included complication rate and type (e.g., acute blood loss anemia [ABLA], partial/total flap loss, etc.). Multivariable logistic regression was performed to assess the impact of fluid volume on patient outcomes. A total of 115 patients (mean age of 51.3 ± 10.5 years) underwent 188 abdominally based free flaps. Deep inferior epigastric artery perforator flaps were performed most often (n = 91), followed by muscle-sparing transverse rectus abdominis flaps (n = 88). Multivariable logistic regression demonstrated that high perioperative fluid administration (≥9,000 mL) was associated with increased odds of medical complications (odds ratio [OR] = 21.7; confidence interval [CI]: 5.54–84.5; p < 0.001). Patients with high fluid administration volumes experienced an increased (but nonstatistically significant) flap complication rate (OR = 2.96; CI: 0.89–9.88; p = 0.08) and developed ABLA at a higher rate (OR = 15.86; CI: 5.30–46.4; p < 0.001). High-volume resuscitation (≥9,000 mL) was associated with increased odds of ABLA as well as a greater likelihood of medical and flap complications in patients undergoing abdominally based free flaps for breast reconstruction. These data should be used to guide the development of protocols within institutions, which perform free flaps for breast reconstruction.
The Future of Robotics in Plastic and Reconstructive Surgery
Payne, Camryn, Martinez, Casey , Spronsen, Nicole Van , Shrout, Max A., Morris, Bryn E., Casey, William J., Rhee, Daniel H. , Reece, Edward, Yi, Johnny , Rebecca, Alanna M. , Payne, Cynthia S. , Van Spronsen, Nicole, Shrout, Max, Casey, William, Rhee, Daniel, Rebecca, Alanna, Payne, Camryn S , Payne, Camryn, Jungbauer, Walter N

Mayo Clinic

Annals of Plastic Surgery | May 1, 2025 | Volume: 94 | Issue: 5S | Pages: S421-S424

10.1097/sap.0000000000004278 | PMID 40310003 Get It

Abstract Robots have been used effectively in plastic and reconstructive surgery (PRS) for reconstruction. The utilization of robotics in all surgical specialties is expanding with the goal of offering the most appropriate patient-centered care possible, especially in complex multidisciplinary cases. Despite the safety, efficiency, and reproducibility of robotics in PRS, there is a paucity of required and formalized training in PRS residency programs. The ACGME and industry published guidelines were investigated. Robotic surgery case logs of Mayo Clinic Arizona General Surgery residents were analyzed with attention to equivalency certification (EQ). Over the past 5 years, the equivalency certification from Intuitive (Sunnyvale, CA) was obtained by 30% of all general surgery residents at our institution (range, 0–100). The case numbers to obtain the equivalence certification are industry recommendations, and proficiency is determined by the program director. The ACGME does not mandate robotics training in general surgery residency. According to the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES), trainees must complete 20 console cases and 10 bedside cases to become industry certified. With respect to training and advancing the field, PRS residents could successfully obtain certification in their residency programs. The minimum case requirement recommended by SAGES is not burdensome and can ensure robotic privileges in PRS practice immediately following graduation. By improving the training for minimally invasive robotic surgery in plastic surgery, patients and healthcare systems benefit from improved quality of life outcomes and decreased postoperative length of stay, which results in less strain on our entire medical system.