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5486 citation(s) found for "Yu, Stephen".

Abstract 13990: ECG Interpretation Proficiency of Healthcare Professionals
Kashou, Anthony H. , Beckman, Thomas J. , Anavekar, Nandan S., Cullen, Michael W. , Angstman, Kurt B. , Shapiro, Brian P. , Wiley, Brandon W., Kates, Andrew M., Huneycutt, David, Braisted, Andrew , Grauer, Ken, OʼBrien, Kevin , Kaul, Viren , Gambhir, Harvir Singh , Knohl, Stephen J. , Albert, D.J. , Kligfield, Paul, Macfarlane, Peter W. , Noseworthy, Peter A. , Sandefur, Benjamin J. , Smith, Stephen W. , Baranchuk, Adrián , May, Adam M.

Mayo Clinic

Circulation | December 19, 2023 | Volume: 148 | Issue: Suppl_1 | Pages: No page available

10.1161/circ.148.suppl_1.13990 Get It

Background: ECG interpretation is crucial in medical practice, but professionals struggle with achieving and maintaining competency. Identifying proficiency gaps aids in designing educational interventions. Methods: Medical professionals from various disciplines interpreted 30 12-lead ECGs containing commonly taught urgent and non-urgent findings. Performance metrics evaluated were overall adjusted score (% of correctly identified findings using a point-value score based on clinical relevance), unadjusted score (% of correctly identified findings), interpretation time per ECG, and self-reported confidence (rated on an ordinal scale of 0 [not confident], 1 [somewhat confident], or 2 [confident]). Results: Among 1206 participants, there were 72 (6%) primary care physicians (PCPs), 146 (12%) cardiology fellows-in-training (FIT), 353 (29%) resident physicians, 182 (15%) medical students, 84 (7%) advanced practice providers (APPs), 120 (10%) nurses, 249 (21%) allied health professionals, 571 (47%) physicians, and 453 (38%) non-physicians. Participants had a mean adjusted score of 46.9% (± 15.9%), unadjusted score of 56.4% (± 17.2%), interpretation time of 142 seconds (± 67 seconds), and confidence of 0.83 (± 0.53) (Table 1) . Performance varied across groups; cardiology FIT had superior performance in all metrics. Physicians generally outperformed non-physicians, with higher overall adjusted score (52% vs. 43%; p<0.01), unadjusted score (62% vs. 52%; p<0.01), and confidence (0.91 vs. 0.80; p<0.01). Unadjusted score for PCPs was higher than nurses and APPs (58% vs. 47% and 51%; p<0.01) but lower than resident physicians (58% vs. 60%; p<0.01). Allied health professionals outperformed nurses and APPs and closely matched resident physicians and PCPs. Conclusions: Significant gaps in ECG interpretation proficiency exist, emphasizing the need for comprehensive, scalable, and accessible educational tools.
Abstract 13633: Modern Treatment Patterns in Incident Pulmonary Arterial Hypertension (PAH) Patients: Real-World Data From the Pulmonary Hypertension Association (PHA) Registry
Kime, Noah , Williams, Kayleen , Rendon, Gabriela Gomez , Mathai, Stephen C. , Mathai, Stephen C , Paoli, Carly J. , Tonelli, Adriano R. , Cajigas, Héctor , Khan, Sarah L. , Sahay, Sandeep

Mayo Clinic

Circulation | December 19, 2023 | Volume: 148 | Issue: Suppl_1 | Pages: No page available

10.1161/circ.148.suppl_1.13633 Get It

Purpose: New 2022 European Society of Cardiology/European Respiratory Society PAH guidelines recommend treatment guided by a multi-parameter risk assessment. 1 Patients with low/intermediate risk without cardiopulmonary comorbidities should start dual PAH combination therapy; those with cardiopulmonary comorbidities should be reassessed early for rapid escalation to dual therapy. Initial triple therapy is recommended for high-risk patients. We examined use of dual and triple PAH therapy in the US (before guideline update). Methods: We used the Pulmonary Hypertension Association Registry (PHAR), a prospective US registry of pulmonary hypertension (PH) patients, enrolled within 6 months of their first outpatient visit at one of 54 participating PH care centers in the US, between Sep 2015-Jun 2022. We included adults (≥18 years at enrollment) with incident PAH (newly diagnosed and treated within 6 months of enrollment) and ≥1 follow-up clinic visit post baseline visit. Chronic thromboembolic PH patients were excluded. Results: We analyzed (descriptive statistics) 794 incident patients (baseline characteristics in Table 1). Treatment patterns at baseline (n=794)/last follow-up visit (n=610) were 289 (36.4%)/102 (16.7%) on monotherapy, 419 (52.8%)/314 (51.5%) on dual combination, 83 (10.5%)/179 (29.3%) on triple combination therapy, respectively. Mean time from enrollment to dual and triple combination therapy was 86.1 (standard deviation [SD]: 209.0) and 346.1 days (SD: 430.8), respectively. Conclusions: Among incident PHAR patients, half received initial dual and 10% triple upfront combination therapy. At last follow-up, most (>80%) patients had escalated to dual/triple combination therapies. Clinical Implications: At PH care centers, most incident PHAR patients are escalated to dual and triple therapy (at last follow-up) per current guidelines. Reference 1. Humbert M, et al. Eur Heart J. 2022;43:3618-731.
From pain to gain: Leveraging acetaminophen in hepatocyte transplantation for phenylketonuria
Schulze, Ryan J. , Nyberg, Scott L. , Strom, Stephen C , Nyberg, Scott L

Mayo Clinic

Hepatology | December 12, 2023 | Volume: 79 | Issue: 5 | Pages: 973-975

10.1097/hep.0000000000000713 | PMID 38085850 Get It

Combined Lateral Closing and Medial Opening-Wedge Proximal Humerus Osteotomy in an Adolescent with Extreme Varus Deformity
Oeding, Jacob F. , Jacobson, Nathan J , Wentworth, Adam, Sems, S.A. , Stans, Anthony A. , Barlow, Jonathan D. , Wentworth, Adam J , Sems, Stephen A , Barlow, Jonathan D , Oeding, Jacob F

Mayo Clinic

JBJS Case Connector | December 8, 2023 | Volume: 13 | Issue: 4 | Pages: No page available

10.2106/jbjs.cc.23.00426 | PMID 38064580 Get It

Case: This report describes the case of an athletic 12-year-old boy who presented with a 64° left proximal humeral varus angulation deformity and physeal bar secondary to multiple operations for a proximal humeral metaphyseal cystic lesion and pathologic fracture. Using a combined lateral closing and medial opening-wedge osteotomy, a 68° valgus correction was achieved with excellent clinical and functional outcomes at 16-month follow-up. Forward flexion increased from 120 to 170° preoperatively to postoperatively while abduction improved from 110° preoperatively to 170° postoperatively. Conclusion: A combined lateral closing and medial opening-wedge osteotomy of the proximal humerus can successfully treat cases of extreme proximal humerus varus in the growing shoulder where unilateral or dome osteotomies are not suitable.
Efficacy of Two Dose Regimens of Subcutaneous Fremanezumab Versus Placebo for the Preventive Treatment of Chronic Migraine (S32.005)
Silberstein, Stephen D., Aycardi, Ernesto, Bigal, Marcelo E. , Yeung, Paul, Blankenbiller, Tricia , Grozinski‐Wolff, Melissa, Yang, Ronghua , Ma, Yuju, Dodick, David W. , Goadsby, Peter J.

Mayo Clinic

Neurology | December 7, 2023 | Volume: 90 | Issue: 15_supplement | Pages: No page available

10.1212/wnl.90.15_supplement.s32.005 Get It

Primary Results of PROMISE-1 (Prevention Of Migraine via Intravenous eptinezumab Safety and Efficacy–1) Trial: a Phase 3, Randomized, Double-blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Eptinezumab for Prevention of Frequent Episo
Saper, Joel R., Kudrow, David, Hirman, Joe, Silberstein, Stephen D., Chakhava, George, Smith, Jeff , Lipton, Richard B. , Dodick, David W.

Mayo Clinic

Neurology | December 7, 2023 | Volume: 90 | Issue: 15_supplement | Pages: No page available

10.1212/wnl.90.15_supplement.s20.001 Get It

Arteriovenous Fistula Presenting as Progressive Bifrontal Intracerebral Hemorrhage (P6.209)
Cox, Benjamin C. , Johnson, Stephen A. , Scharf, Eugene

Mayo Clinic

Neurology | December 7, 2023 | Volume: 90 | Issue: 15_supplement | Pages: No page available

10.1212/wnl.90.15_supplement.p6.209 Get It

Efficacy Of Fremanezumab in Patients With Chronic Migraine With or Without Concomitant Use of Preventive Medication (P4.099)
Silberstein, Stephen D., Yeung, Paul, Blankenbiller, Tricia , Ning, Xiaoping , Yang, Ronghua , Ma, Yuju, Aycardi, Ernesto, Bigal, Marcelo E. , Goadsby, Peter J. , Dodick, David W.

Mayo Clinic

Neurology | December 7, 2023 | Volume: 90 | Issue: 15_supplement | Pages: No page available

10.1212/wnl.90.15_supplement.p4.099 Get It

Erenumab Immunogenicity: a Pooled Analysis of Phase 2 and Phase 3 Migraine Prevention Clinical Trials (P4.098)
Vargas, Bert B., Starling, Amaal J. , Silberstein, Stephen D., Zhou, Yanchen , Trotman, Marie‐Louise, Xue, Fei , Sahebkar-Moghaddam, Farhad, Picard, Hernàn , Mikol, Daniel D.

Mayo Clinic

Neurology | December 7, 2023 | Volume: 90 | Issue: 15_supplement | Pages: No page available

10.1212/wnl.90.15_supplement.p4.098 Get It