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80 citation(s) found for "Lu, Lichun".

Photo-Cross-Linked Hybrid Polymer Networks Consisting of Poly(propylene fumarate) and Poly(caprolactone fumarate): Controlled Physical Properties and Regulated Bone and Nerve Cell Responses
Wang, Shanfeng , Kempen, Diederik H.R. , Simha, N.K., Lewis, Jack L. , Windebank, Anthony J. , Yaszemski, Michael J. , Lu, Lichun

Mayo Clinic

Biomacromolecules | February 29, 2008 | Volume: 9 | Issue: 4 | Pages: 1229-1241

10.1021/bm7012313 | PMID 18307311 Get It

Synthesis and Evaluation of Novel Biodegradable Hydrogels Based on Poly(ethylene glycol) and Sebacic Acid as Tissue Engineering Scaffolds
Kim, Jinku , Lee, Kee‐Won , Hefferan, Theresa E., Currier, Bradford L. , Yaszemski, Michael J. , Lu, Lichun

Mayo Clinic

Biomacromolecules | December 12, 2007 | Volume: 9 | Issue: 1 | Pages: 149-157

10.1021/bm700924n | PMID 18072747 Get It

Characterization of Photo-Cross-Linked Oligo[poly(ethylene glycol) fumarate] Hydrogels for Cartilage Tissue Engineering
Dadsetan, Mahrokh, Szatkowski, J. , Yaszemski, Michael J. , Lu, Lichun

Mayo Clinic

Biomacromolecules | April 10, 2007 | Volume: 8 | Issue: 5 | Pages: 1702-1709

10.1021/bm070052h | PMID 17419584 Get It

Poly(propylene fumarate) Bone Tissue Engineering Scaffold Fabrication Using Stereolithography:  Effects of Resin Formulations and Laser Parameters
Lee, Kee‐Won , Fox, Bradley C., Ritman, Erik L., Yaszemski, Michael J. , Lu, Lichun , Wang, Shanfeng

Mayo Clinic

Biomacromolecules | February 28, 2007 | Volume: 8 | Issue: 4 | Pages: 1077-1084

10.1021/bm060834v | PMID 17326677 Get It

Fabrication and Characterization of Poly(Propylene Fumarate) Scaffolds with Controlled Pore Structures Using 3-Dimensional Printing and Injection Molding
Lee, Kee‐Won , Lu, Lichun , Jabbari, Esmaiel , Currier, Bradford L. , Yaszemski, Michael J. , Wang, Shanfeng

Mayo Clinic

Tissue Engineering | October 20, 2006 | Volume: 12 | Issue: 10 | Pages: 2801-2811

10.1089/ten.2006.12.2801 | PMID 17518649 Get It

Bone-Tissue-Engineering Material Poly(propylene fumarate):  Correlation between Molecular Weight, Chain Dimensions, and Physical Properties
Wang, Shanfeng , Lu, Lichun , Yaszemski, Michael J.

Mayo Clinic

Biomacromolecules | June 10, 2006 | Volume: 7 | Issue: 6 | Pages: 1976-1982

10.1021/bm060096a | PMID 16768422 Get It

Effects of Dynamic Fluid Pressure on Chondrocytes Cultured in Biodegradable Poly(glycolic acid) Fibrous Scaffolds
Lu, Lichun , Pederson, Larry, Jabbari, Esmaiel , Currier, Bradford L. , O’Driscoll, Shawn W. , Yaszemski, Michael J. , Zhu, Xun , Fitzsimmons, James S

Mayo Clinic

Tissue Engineering | January 13, 2006 | Volume: 11 | Issue: 11-12 | Pages: 1852-1859

10.1089/ten.2005.11.1852 | PMID 16411831 Get It

Synthesis, Material Properties, and Biocompatibility of a Novel Self-Cross-Linkable Poly(caprolactone fumarate) as an Injectable Tissue Engineering Scaffold
Jabbari, Esmaiel , Lu, Lichun , Gruetzmacher, James A., Ameenuddin, Syed, Hefferan, Theresa E., Currier, Bradford L. , Windebank, Anthony J. , Yaszemski, Michael J. , Wang, Shanfeng

Mayo Clinic

Biomacromolecules | September 12, 2005 | Volume: 6 | Issue: 5 | Pages: 2503-2511

10.1021/bm050206y | PMID 16153086 Get It

A Biodegradable and Cross-Linkable Multiblock Copolymer Consisting of Poly(propylene fumarate) and Poly(ε-caprolactone):  Synthesis, Characterization, and Physical Properties
Wang, Shanfeng , Lu, Lichun , Gruetzmacher, James A., Currier, Bradford L. , Yaszemski, Michael J.

Mayo Clinic

Macromolecules | August 16, 2005 | Volume: 38 | Issue: 17 | Pages: 7358-7370

10.1021/ma050884c Get It

Biological Activity of rhBMP-2 Released From PLGA Microspheres
Oldham, Jacob B., Lu, Lichun , Zhu, and X., Porter, Blaise D., Hefferan, T. E., Larson, David, Currier, Bradford L. , Mikos, Antonios G. , Yaszemski, Michael J.

Mayo Clinic

Journal of Biomechanical Engineering | July 27, 2002 | Volume: 122 | Issue: 3 | Pages: 289-292

10.1115/1.429662 | PMID 10923299 Get It

Human recombinant bone morphogenetic protein-2 (rhBMP-2) has been proven effective in stimulating the regeneration of bone in both skeletal and extraskeletal locations. Through encapsulation within, and release from, biodegradable poly(DL-lactic-co-glycolic acid) (PLGA) microspheres, a proven vehicle for sustained delivery of various proteins, the local concentrations of rhBMP-2 could be maintained at optimal levels to stimulate bone regeneration and remodeling at the site of healing in diverse clinical settings. Thus the purpose of this work was to investigate the encapsulation of rhBMP-2 in PLGA microspheres and its biologic activity upon release. Using in vitro tests in simulated body fluids, the effect of rhBMP-2 released from PLGA microspheres upon osteoblast cell cultures was found to be statistically similar to the effect produced by positive controls consisting of nonencapsulated aqueous rhBMP-2 in simulated body fluids. This clarifies an important step in skeletal tissue engineering strategies aimed at the use of encapsulated rhBMP-2 to stimulate bone regeneration and remodeling. [S0148-0731(00)01303-0]