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898 citation(s) found for "Cook, D A".

Information needs of generalists and specialists using online best-practice algorithms to answer clinical questions
Cook, David A. , Sorensen, Kristi J., Linderbaum, Jane A. , Pencille, Laurie J., Rhodes, Deborah J.

Mayo Clinic

Journal of the American Medical Informatics Association | January 5, 2017 | Volume: 24 | Issue: 4 | Pages: 754-761

10.1093/jamia/ocx002 | PMID 28339685 Get It

AbstractObjective: To better understand clinician information needs and learning opportunities by exploring the use of best-practice algorithms across different training levels and specialties.Methods: We developed interactive online algorithms (care process models [CPMs]) that integrate current guidelines, recent evidence, and local expertise to represent cross-disciplinary best practices for managing clinical problems. We reviewed CPM usage logs from January 2014 to June 2015 and compared usage across specialty and provider type.Results: During the study period, 4009 clinicians (2014 physicians in practice, 1117 resident physicians, and 878 nurse practitioners/physician assistants [NP/PAs]) viewed 140 CPMs a total of 81 764 times. Usage varied from 1 to 809 views per person, and from 9 to 4615 views per CPM. Residents and NP/PAs viewed CPMs more often than practicing physicians. Among 2742 users with known specialties, generalists (N = 1397) used CPMs more often (mean 31.8, median 7 views) than specialists (N = 1345; mean 6.8, median 2; P < .0001). The topics used by specialists largely aligned with topics within their specialties. The top 20% of available CPMs (28/140) collectively accounted for 61% of uses. In all, 2106 clinicians (52%) returned to the same CPM more than once (average 7.8 views per topic; median 4, maximum 195). Generalists revisited topics more often than specialists (mean 8.8 vs 5.1 views per topic; P < .0001).Conclusions: CPM usage varied widely across topics, specialties, and individual clinicians. Frequently viewed and recurrently viewed topics might warrant special attention. Specialists usually view topics within their specialty and may have unique information needs.
Reporting quality and risk of bias in randomised trials in health professions education
Horsley, Tanya , Galipeau, James , Zeiter, Jeanie, Hamstra, Stanley J. , Cook, David A. , Hamstra, Stanley J , Petkovic, Jennifer

Mayo Clinic

Medical Education | December 17, 2016 | Volume: 51 | Issue: 1 | Pages: 61-71

10.1111/medu.13130 | PMID 27981660 Get It

Context Complete reporting of research is essential to enable consumers to accurately appraise, interpret and apply findings. Quality appraisal checklists are giving way to tools that judge the risk for bias. Objectives We sought to determine the prevalence of these complementary aspects of research reports (completeness of reporting and perceived risk for bias) of randomised studies in health professions education. Methods We searched bibliographic databases for randomised studies of health professions education. We appraised two cohorts representing different time periods (2008–2010 and 2014, respectively) and worked in duplicate to apply the CONSORT guidelines and Cochrane Risk of Bias tool. We explored differences between time periods using independent‐samples t ‐tests or the chi‐squared test, as appropriate. Results We systematically identified 180 randomised studies (2008–2010, n = 150; 2014, n = 30). Frequencies of reporting of CONSORT elements within full‐text reports were highly variable and most elements were reported in fewer than 50% of studies. We found a statistically significant difference in the CONSORT reporting index (maximum score: 500) between the 2008–2010 (mean ± standard deviation [SD]: 242.7 ± 55.6) and 2014 (mean ± SD: 311.6 ± 53.2) cohorts (p < 0.001). High or unclear risk for bias was most common for allocation concealment (157, 87%) and blinding of participants (147, 82%), personnel (152, 84%) and outcome assessors (112, 62%). Most risk for bias elements were judged to be unclear (range: 51–84%). Risk for bias elements significantly improved over time for blinding of participants (p = 0.007), incomplete data (p < 0.001) and the presence of other sources of bias (p < 0.001). Conclusions Reports of randomised studies in health professions education frequently omit elements recommended by the CONSORT statement. Most reports were assessed as having a high or unclear risk for bias. Greater attention to how studies are reported at study outset and in manuscript preparation could improve levels of complete transparent reporting.
Using In-Training Evaluation Report (ITER) Qualitative Comments to Assess Medical Students and Residents: A Systematic Review
Sawatsky, Adam P. , Ginsburg, Shiphra , Cook, David A. , Hatala, Rose , Dudek, Nancy L.

Mayo Clinic

Academic Medicine | December 7, 2016 | Volume: 92 | Issue: 6 | Pages: 868-879

10.1097/acm.0000000000001506 | PMID 28557953 Get It

Purpose In-training evaluation reports (ITERs) constitute an integral component of medical student and postgraduate physician trainee (resident) assessment. ITER narrative comments have received less attention than the numeric scores. The authors sought both to determine what validity evidence informs the use of narrative comments from ITERs for assessing medical students and residents and to identify evidence gaps. Method Reviewers searched for relevant English-language studies in MEDLINE, EMBASE, Scopus, and ERIC (last search June 5, 2015), and in reference lists and author files. They included all original studies that evaluated ITERs for qualitative assessment of medical students and residents. Working in duplicate, they selected articles for inclusion, evaluated quality, and abstracted information on validity evidence using Kane’s framework (inferences of scoring, generalization, extrapolation, and implications). Results Of 777 potential articles, 22 met inclusion criteria. The scoring inference is supported by studies showing that rich narratives are possible, that changing the prompt can stimulate more robust narratives, and that comments vary by context. Generalization is supported by studies showing that narratives reach thematic saturation and that analysts make consistent judgments. Extrapolation is supported by favorable relationships between ITER narratives and numeric scores from ITERs and non-ITER performance measures, and by studies confirming that narratives reflect constructs deemed important in clinical work. Evidence supporting implications is scant. Conclusions The use of ITER narratives for trainee assessment is generally supported, except that evidence is lacking for implications and decisions. Future research should seek to confirm implicit assumptions and evaluate the impact of decisions.
Guideline for Reversal of Antithrombotics in Intracranial Hemorrhage: Executive Summary. A Statement for Healthcare Professionals From the Neurocritical Care Society and the Society of Critical Care Medicine
Frontera, Jennifer , Lewin, John J. , Aisiku, Imo, Alexandrov, Anne W. , Cook, Aaron M. , Zoppo, Gregory J. del, Kumar, Monisha A. , Stiefel, Michael , Teitelbaum, Jeanne , Wartenberg, Katja E. , Zerfoss, Cindy, Frontera, Jennifer A, Rabinstein, Alejandro A. , Aisiku, Imoigele P. , Peerschke, Ellinor I.B. , Cook, Aaron M , Frontera, Jennifer

Mayo Clinic

Critical Care Medicine | November 18, 2016 | Volume: 44 | Issue: 12 | Pages: 2251-2257

10.1097/ccm.0000000000002057 | PMID 27858808 Get It

The monitoring of activity at home after total hip arthroplasty
Toogood, Paul , Spear, Joshua A. , Cook, S. M., Taunton, Michael J. , Abdel, Matthew P. , Cook, David J. , Taunton, Michael J

Mayo Clinic

The Bone & Joint Journal | November 1, 2016 | Volume: 98-B | Issue: 11 | Pages: 1450-1454

10.1302/0301-620x.98b11.bjj-2016-0194.r1 | PMID 27803219 Get It

Aims Total hip arthroplasty (THA) has well known subjective benefits, but little is known objectively about the recovery of mobility in the early post-operative period. Patients and Methods A total of 33 patients aged > 60 years who underwent elective primary THA had their activity monitored for 30 days post-operatively using an at-home (Fitbit) ankle accelerometer. Their mean age was 70.7 years (61 to 86); 15 (45.5%) were female. The rate of compliance and the mean level of activity were determined. Comparisons between subgroups based on age, body mass index (BMI), surgical approach, and the destination of the patients when discharged were also performed. Results The mean compliance over the 30 days was 26.7 days (16 to 30; 89%) of use. The mean number of steps increased from 235 (5 to 1152) to 2563 (87 to 7280) (p < 0.001) between the first and the 30th post-operative day. Age < 70 years and an anterior surgical approach were significantly associated with higher levels of activity (1600 to 2400 (p = 0.016 to 0.031) and 1000 to 1800 (p = 0.017 to 0.037) more steps per day, respectively) between the second and the fourth week post-operatively. There was also a trend towards higher levels of activity in those who were discharged to their home rather than to a nursing facility (a mean of 1500 more steps per day, p = 0.02). BMI greater or less than 30 kg/m 2 was not predictive of activity (p = 0.45 to 0.98). Conclusion At-home remote mobility monitoring using existing commercially available technology is feasible in patients who have undergone THA. It showed a clear trend towards increased activity with the passage of time. Additionally, the remote device was able to detect differences in levels of activity clearly between patients in relation to variables of interest including age, BMI, surgical approach, and the destination of the patient at the time of discharge from hospital. Such monitoring may allow for the early identification and targeted intervention in patients who recover slowly. Cite this article: Bone Joint J 2016;98-B:1450–4.
IC‐01‐05: Neuropathologic Features of AV1451 TAU Pet Autoradiography in Dementia
Curran, Geoffry L., Fang, Ping , Josephs, Keith A. , Parisi, Joseph E., Bruinsma, Tyler J. , Petrucelli, Leonard , Cook, Casey , Petersen, Ronald C. , Lowe, Val J. , Murray, Melissa E. , Kantarci, Kejal , Boeve, Bradley F. , Pandey, Mukesh K. , Knopman, David S. , Jones, David T. , Dickson, Dennis W. , Jack, Clifford R.

Mayo Clinic

Alzheimer's & Dementia | October 17, 2016 | Volume: 12 | Issue: 7S_Part_1 | Pages: No page available

10.1016/j.jalz.2016.06.065 Get It

Effect of antiplatelet therapy on mortality and acute lung injury in critically ill patients: A systematic review and meta-analysis
Sethi, Jaskaran , Villablanca, Pedro , Ali, Muhammad , Kumar, Rohit , Baruah, Anushka , Bhatia, Nirmanmoh , Agrawal, Sahil , Hussain, Zeeshan , Shamoun, Fadi , Augoustides, John T., Shamoun, Fadi E., Ramakrishna, Harish , Mohananey, Divyanshu

Mayo Clinic

Annals of Cardiac Anaesthesia | October 7, 2016 | Volume: 19 | Issue: 4 | Pages: 626-637

10.4103/0971-9784.191576 | PMID 27716693 Get It

Aim: Platelet function is intricately linked to the pathophysiology of critical Illness, and some studies have shown that antiplatelet therapy (APT) may decrease mortality and incidence of acute respiratory distress syndrome (ARDS) in these patients. Our objective was to understand the efficacy of APT by conducting a meta-analysis. Materials and Methods: We conducted a meta-analysis using PubMed, Central, Embase, The Cochrane Central Register, the ClinicalTrials.gov Website, and Google Scholar. Studies were included if they investigated critically ill patients receiving antiplatelet therapy and mentioned the outcomes being studied (mortality, duration of hospitalization, ARDS, and need for mechanical ventilation). Results: We found that there was a significant reduction in all-cause mortality in patients on APT compared to control (odds ratio [OR]: 0.83; 95% confidence interval [CI]: 0.70–0.97). Both the incidence of acute lung injury/ARDS (OR: 0.67; 95% CI: 0.57–0.78) and need for mechanical ventilation (OR: 0.74; 95% CI: 0.60–0.91) were lower in the antiplatelet group. No significant difference in duration of hospitalization was observed between the two groups (standardized mean difference: −0.02; 95% CI: −0.11–0.07). Conclusion: Our meta-analysis suggests that critically ill patients who are on APT have an improved survival, decreased incidence of ARDS, and decreased need for mechanical ventilation.
Does Anterior Cruciate Ligament Innervation Matter for Joint Function and Development of Osteoarthritis?
Nagelli, Christopher V. , Kuroki, Kei , Bozynski, Chantelle C. , Ma, Richard , Hewett, Timothy E. , Cook, James L.

Mayo Clinic

The Journal of Knee Surgery | September 20, 2016 | Volume: 30 | Issue: 04 | Pages: 364-371

10.1055/s-0036-1592145 | PMID 27648746 Get It

Motivation to learn: an overview of contemporary theories
Cook, David A. , Artino, Anthony R.

Mayo Clinic

Medical Education | September 15, 2016 | Volume: 50 | Issue: 10 | Pages: 997-1014

10.1111/medu.13074 | PMID 27628718 Get It

Objective To succinctly summarise five contemporary theories about motivation to learn, articulate key intersections and distinctions among these theories, and identify important considerations for future research. Results Motivation has been defined as the process whereby goal‐directed activities are initiated and sustained. In expectancy‐value theory, motivation is a function of the expectation of success and perceived value. Attribution theory focuses on the causal attributions learners create to explain the results of an activity, and classifies these in terms of their locus, stability and controllability. Social‐ cognitive theory emphasises self‐efficacy as the primary driver of motivated action, and also identifies cues that influence future self‐efficacy and support self‐regulated learning. Goal orientation theory suggests that learners tend to engage in tasks with concerns about mastering the content (mastery goal, arising from a ‘growth’ mindset regarding intelligence and learning) or about doing better than others or avoiding failure (performance goals, arising from a ‘fixed’ mindset). Finally, self‐determination theory proposes that optimal performance results from actions motivated by intrinsic interests or by extrinsic values that have become integrated and internalised. Satisfying basic psychosocial needs of autonomy, competence and relatedness promotes such motivation. Looking across all five theories, we note recurrent themes of competence, value, attributions, and interactions between individuals and the learning context. Conclusions To avoid conceptual confusion, and perhaps more importantly to maximise the theory‐building potential of their work, researchers must be careful (and precise) in how they define, operationalise and measure different motivational constructs. We suggest that motivation research continue to build theory and extend it to health professions domains, identify key outcomes and outcome measures, and test practical educational applications of the principles thus derived.
Characterization of Exercise and Alcohol Self-Management Behaviors of Type 1 Diabetes Patients on Insulin Pump Therapy
Grando, Adela , Groat, Danielle , Soni, Hiral , Boyle, Mary , Bailey, Marilyn, Thompson, Bithika , Grando, Maria Adela, Cook, Curtiss B. , Grando, Maria Adela

Mayo Clinic

Journal of Diabetes Science and Technology | September 5, 2016 | Volume: 11 | Issue: 2 | Pages: 240-246

10.1177/1932296816663746 | PMID 27595712 Get It

Background: There is a lack of systematic ways to analyze how diabetes patients use their insulin pumps to self-manage blood glucose to compensate for alcohol ingestion and exercise. The objective was to analyze “real-life” insulin dosing decisions occurring in conjunction with alcohol intake and exercise among patients using insulin pumps. Methods: We recruited adult type 1 diabetes (T1D) patients on insulin pump therapy. Participants were asked to maintain their daily routines, including those related to exercising and consuming alcohol, and keep a 30-day journal on exercise performed and alcohol consumed. Thirty days of insulin pump data were downloaded. Participants’ actual insulin dosing behaviors were compared against their self-reported behaviors in the setting of exercise and alcohol. Results: Nineteen T1D patients were recruited and over 4000 interactions with the insulin pump were analyzed. The analysis exposed variability in how subjects perceived the effects of exercise/alcohol on their blood glucose, inconsistencies between self-reported and observed behaviors, and higher rates of blood glucose control behaviors for exercise versus alcohol. Conclusion: Compensation techniques and perceptions on how exercise and alcohol affect their blood glucose levels vary between patients. Improved individualized educational techniques that take into consideration a patient’s unique life style are needed to help patients effectively apply alcohol and exercise compensation techniques.