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65 citation(s) found for "DeTure, Michael".

O2‐05‐04: The involvement of the 5lipoxygenase pathway in tauopathy
Praticò, Domenico , Giannopoulos, Phillip F., Li, Jianguo , DeTure, Michael , Li, Jian-Guo, Dickson, Dennis W.

Mayo Clinic

Alzheimer's & Dementia | December 15, 2015 | Volume: 11 | Issue: 7S_Part_4 | Pages: No page available

10.1016/j.jalz.2015.07.157 Get It

P3‐004: TDP‐43 FILAMENT ASSEMBLY IS INHIBITED BY HEAT SHOCK PROTEINS
DeTure, Michael , Carlomagno, Yari , Davis, Mary Dabney , Lin, Wen‐Lang, Petrucelli, Leonard , Zhang, Yong‐Jie

Mayo Clinic

Alzheimer's & Dementia | September 6, 2014 | Volume: 10 | Issue: 4S_Part_17 | Pages: No page available

10.1016/j.jalz.2014.05.1091 Get It

P1‐372: Regulation of the Hsp90 chaperone complex by HDAC6
Cook, Casey , Dunmore, Judy H., DeTure, Michael , Petrucelli, Leonard , Gendron, Tania F.

Mayo Clinic

Alzheimer's & Dementia | July 11, 2010 | Volume: 6 | Issue: 4S_Part_9 | Pages: No page available

10.1016/j.jalz.2010.05.926 Get It

P1‐371: Characteristics of cytosolic hyperphosphorylated tau species in rTg4510 mouse brain
DeTure, Michael , Ebrahim, Abdul-Shukkur, Christensen, S⊘ren, Kang, Dongcheul, Knight, Josh , Petrucelli, Leonard , Yen, Shu‐Hui, Lewis, Jada , Sahara, Naruhiko , Volbracht, Christiane

Mayo Clinic

Alzheimer's & Dementia | July 11, 2010 | Volume: 6 | Issue: 4S_Part_9 | Pages: No page available

10.1016/j.jalz.2010.05.925 Get It

Tau Suppression in a Neurodegenerative Mouse Model Improves Memory Function
SantaCruz, Karen S., Lewis, Jada , Spires‐Jones, Tara L. , Paulson, Jennifer , Kotilinek, Linda, Guimaraes, Aaron, DeTure, Michael , Ramsden, M., Forster, Colleen L. , Yue, Mei, Orne, Jennifer D., Janus, Christopher , Mariash, Ami, Kuskowski, Michael A., Ashe, Karen H. , Ingelsson, Martin , McGowan, Eileen , Hyman, Bradley T. , Hutton, M.

Mayo Clinic

Science | July 14, 2005 | Volume: 309 | Issue: 5733 | Pages: 476-481

10.1126/science.1113694 | PMID 16020737 Get It

Neurofibrillary tangles (NFTs) are the most common intraneuronal inclusion in the brains of patients with neurodegenerative diseases and have been implicated in mediating neuronal death and cognitive deficits. Here, we found that mice expressing a repressible human tau variant developed progressive age-related NFTs, neuronal loss, and behavioral impairments. After the suppression of transgenic tau, memory function recovered, and neuron numbers stabilized, but to our surprise, NFTs continued to accumulate. Thus, NFTs are not sufficient to cause cognitive decline or neuronal death in this model of tauopathy.