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45 citation(s) found for "Ware, M".

Ventilator-induced lung injury: in vivo and in vitro mechanisms
Matthay, Michael A. , Bhattacharya, Sunita , Gaver, Donald P. , Ware, Lorraine B. , Syrkina, Olga, Eyal, Fabien, Hubmayr, Rolf D., Lim, Lina H. K.

Mayo Clinic

American Journal of Physiology-Lung Cellular and Molecular Physiology | March 3, 2015 | Volume: 283 | Issue: 4 | Pages: L678-L682

10.1152/ajplung.00154.2002 | PMID 12225942 Get It

A lung-protective ventilator strategy significantly reduces mortality in patients with acute lung injury. Substantial progress has been made in understanding how mechanical stress can injure the lung, both in terms of alterations in barrier properties of the pulmonary endothelium and epithelium as well as in stimulating proinflammatory responses of macrophages and neutrophils.
Evidence gaps in the management of sickle cell disease: A summary of needed research
Savage, William, Buchanan, George R., Yawn, Barbara P. , Afenyi‐Annan, Araba, Ballas, Samir K. , Goldsmith, Jonathan C. , James, Allison , John‐Sowah, Joylene, Jordan, Lanetta, Lottenberg, Richard , Murad, M. Hassan , Ortíz, Eduardo , Tanabe, Paula , Lanzkron, Sophie , Hassell, Kathryn Louise , Ware, Russell E. , Murad, M Hassan , James, Andra H

Mayo Clinic

American Journal of Hematology | January 12, 2015 | Volume: 90 | Issue: 4 | Pages: 273-275

10.1002/ajh.23945 | PMID 25639238 Get It

Management of Sickle Cell Disease
Yawn, Barbara P. , Buchanan, George R., Afenyi‐Annan, Araba, Ballas, Samir K. , James, Allison , Jordan, Lanetta, Lanzkron, Sophie , Lottenberg, Richard , Savage, William, Tanabe, Paula , Murad, M. Hassan , Goldsmith, Jonathan C. , Ortíz, Eduardo , Fulwood, Robinson, Horton, Ann, John‐Sowah, Joylene, Hassell, Kathryn Louise , Ware, Russell E. , Murad, M Hassan , James, Andra H

Mayo Clinic

JAMA | September 9, 2014 | Volume: 312 | Issue: 10 | Pages: 1033

10.1001/jama.2014.10517 | PMID 25203083 Get It

Advancing Alzheimer's disease diagnosis, treatment, and care: Recommendations from the Ware Invitational Summit
Naylor, Mary D. , Karlawish, Jason , Arnold, Steven E. , Khachaturian, Ara S. , Khachaturian, Zaven S., Baumgart, Matthew, Banerjee, Sube , Beck, Cornelia, Blennow, Kaj , Brookmeyer, Ron , Brunden, Kurt R. , Buckwalter, Kathleen C., Comer, Meryl, Covinsky, Kenneth E. , Feinberg, Lynn Friss, Frisoni, Giovanni B. , Guimarães, Renato Maia, Gwyther, Lisa P., Hutton, Michael , Kawas, Claudia H. , Kent, David M. , Kuller, Lewis H. , Langa, Kenneth M. , Mahley, Robert W. , Maslow, Katie, Masters, Colin L. , Meier, Diane E. , Neumann, Peter J. , Paul, Steven M., Petersen, Ronald C. , Sager, Mark A., Sano, Mary , Schenk, Dale, Soares, Holly , Stahl, Sidney M., Stern, Yaakov , Weir, David R. , Trojanowski, John Q. , Frisoni, Giovanni B. , Lee, Virginia M.‐Y. , Green, Colin Richard , Hefti, Franz F. , Sperling, Reisa Anne , Deerlin, Vivianna M. Van , Wolk, David A. , Stern, Yaakov , Masters, Colin L , Kent, David M

Mayo Clinic

Alzheimer's & Dementia | September 7, 2012 | Volume: 8 | Issue: 5 | Pages: 445-452

10.1016/j.jalz.2012.08.001 | PMID 22959699 Get It

AbstractTo address the pending public health crisis due to Alzheimer's disease (AD) and related neurodegenerative disorders, the Marian S. Ware Alzheimer Program at the University of Pennsylvania held a meeting entitled “State of the Science Conference on the Advancement of Alzheimer's Diagnosis, Treatment and Care,” on June 21‐22, 2012. The meeting comprised four workgroups focusing on Biomarkers; Clinical Care and Health Services Research; Drug Development; and Health Economics, Policy, and Ethics. The workgroups shared, discussed, and compiled an integrated set of priorities, recommendations, and action plans, which are presented in this article.
Beyond Mortality: Future Clinical Research in Acute Lung Injury
Spragg, Roger G., Bernard, Gordon R. , Checkley, William , Gajić, Ognjen, Hall, Jesse B., Israel, Elliott, Jain, Manu , Needham, Dale M. , Randolph, Adrienne G. , Rubenfeld, Gordon D., Schoenfeld, David , Ware, Lorraine B. , Young, Duncan , Harabin, Andrea L., Curtis, J. Randall , Guyatt, Gordon , Thompson, Bruce , Randolph, Adrienne G

Mayo Clinic

American Journal of Respiratory and Critical Care Medicine | March 11, 2010 | Volume: 181 | Issue: 10 | Pages: 1121-1127

10.1164/rccm.201001-0024ws | PMID 20224063 Get It

Abstract Mortality in National Heart, Lung and Blood Institute–sponsored clinical trials of treatments for acute lung injury (ALI) has decreased dramatically during the past two decades. As a consequence, design of such trials based on a mortality outcome requires ever-increasing numbers of patients. Recognizing that advances in clinical trial design might be applicable to these trials and might allow trials with fewer patients, the National Heart, Lung and Blood Institute convened a workshop of extramural experts from several disciplines. The workshop assessed the current state of clinical research addressing ALI, identified research needs, and recommended: (1) continued performance of trials evaluating treatments of patients with ALI; (2) development of strategies to perform ALI prevention trials; (3) observational studies of patients without ALI undergoing prolonged mechanical ventilation; and (4) development of a standardized format for reporting methods, endpoints, and results of ALI trials.