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126 citation(s) found for "Ramanan, Vijay K".

O4‐05‐01: Gwas of longitudinal amyloid PET identifies IL1RAP as a new potential Alzheimer's disease target
Kim, Sungeun , Aisen, Paul, Petersen, Ronald C. , Jagust, William J. , Weiner, Michael W. , (ADNI), Alzheimer's Disease Neuroimaging Initiative, Ramanan, Vijay K. , Risacher, Shannon L. , Nho, Kwangsik T. , Shen, Li , Foroud, Tatiana , Toga, Arthur W. , Green, Robert C. , Saykin, Andrew J. , (ADNI), Alzheimer's Disease Neuroimaging Initiative

Mayo Clinic

Alzheimer's & Dementia | December 15, 2015 | Volume: 11 | Issue: 7S_Part_6 | Pages: No page available

10.1016/j.jalz.2015.07.369 Get It

Protective variant for hippocampal atrophy identified by whole exome sequencing
Kim, Sungeun , Risacher, Shannon L. , Shen, Li , Corneveaux, Jason J., Swaminathan, Shanker , Lin, Hai , Inlow, Mark , Siniard, Ashley L., Reiman, Rebecca, Aisen, Paul, Petersen, Ronald , Jack, Clifford R. , Weiner, Michael W. , Baldwin, Clinton T., Lunetta, Kathryn L. , Farrer, Lindsay A. , Furney, Simon J. , Lovestone, Simon , Simmons, Andrew , Mecocci, Patrizia , Vellas, Bruno , Tsolaki, Magda , Kłoszewska, Iwona, McDonald, Brenna C. , Farlow, Martin R. , Study, for the Indiana Memory and Aging, Huentelman, Matthew J. , Saykin, Andrew J. , Initiative, for the Alzheimer's Disease Neuroimaging, Nho, Kwangsik T. , Ramanan, Vijay K. , Liu, Yunlong , Foroud, Tatiana , Green, Robert C. , Soininen, Hilkka S. , Ghetti, Bernardino , Study, for the Indiana Memory and Aging, Initiative, for the Alzheimer's Disease Neuroimaging, Jack, Clifford R , Saykin, Andrew J , Shen, Li , Tsolaki, Magda , Mecocci, Patrizia

Mayo Clinic

Annals of Neurology | January 5, 2015 | Volume: 77 | Issue: 3 | Pages: 547-552

10.1002/ana.24349 | PMID 25559091 Get It

We used whole‐exome sequencing to identify variants other than APOE associated with the rate of hippocampal atrophy in amnestic mild cognitive impairment. An in‐silico predicted missense variant in REST (rs3796529) was found exclusively in subjects with slow hippocampal volume loss and validated using unbiased whole‐brain analysis and meta‐analysis across 5 independent cohorts. REST is a master regulator of neurogenesis and neuronal differentiation that has not been previously implicated in Alzheimer's disease. These findings nominate REST and its functional pathways as protective and illustrate the potential of combining next‐generation sequencing with neuroimaging to discover novel disease mechanisms and potential therapeutic targets. Ann Neurol 2015;77:547–552
P3‐024: NEXT‐GENERATION SEQUENCING OF THE BCHE LOCUS IDENTIFIES A FUNCTIONAL SNP ASSOCIATED WITH ALZHEIMER'S DISEASE BIOMARKERS AND AGE OF ONSET
Kim, Sungeun , Aisen, Paul, Huentelman, Matthew J. , Jagust, William J. , Petersen, Ronald Carl, Shaw, Leslie M. , Trojanowski, John Q. , Weiner, Michael W. , Ramanan, Vijay K. , Nho, Kwangsik T. , Risacher, Shannon L. , Shen, Li , Swaminathan, Shanker , Foroud, Tatiana , Håkonarson, Håkon , Jack, Clifford R. , Potkin, Steven G. , Green, Robert C. , Toga, Arthur W. , Saykin, Andrew J.

Mayo Clinic

Alzheimer's & Dementia | September 6, 2014 | Volume: 10 | Issue: 4S_Part_17 | Pages: No page available

10.1016/j.jalz.2014.05.1111 Get It

O3–01–03: Protective variant for rate of hippocampal volume loss identified by whole exome sequencing in APOE‐ε3ε3 males with MCI
Corneveaux, Jason J., Lin, Hai , Inlow, Mark , Reiman, Rebecca, Aisen, Paul, Petersen, Ronald, Weiner, Michael W. , Baldwin, Clinton T., Simmons, Andrew , Vellas, Bruno , Kłoszewska, Iwona, Farlow, Martin R. , Huentelman, Matthew J. , Nho, Kwangsik T. , Kim, Sungeun , Risacher, Shannon L. , Shen, Li , Swaminathan, Shanker , Ramanan, Vijay K. , Liu, Yunlong , Foroud, Tatiana , Green, Robert C. , Jack, Clifford R. , Farrer, Lindsay A. , Lovestone, Simon , Mecocci, Patrizia , Tsolaki, Magda , Soininen, Hilkka S. , McDonald, Brenna C. , Saykin, Andrew J.

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Alzheimer's & Dementia | October 9, 2013 | Volume: 9 | Issue: 4S_Part_13 | Pages: No page available

10.1016/j.jalz.2013.04.238 Get It

P3–008: Genome‐wide analysis of genetic variants associated with depressive symptoms in older adults
Mackin, Scott, Aisen, Paul, Petersen, Ronald, Weiner, Michael W. , Farlow, Martin R. , Gao, Sujuan , Nho, Kwangsik T. , Swaminathan, Shanker , Kim, Sungeun , Risacher, Shannon L. , Ramanan, Vijay K. , Shen, Li , McDonald, Brenna C. , Ghetti, Bernardino , Saykin, Andrew J. , Green, Robert C.

Mayo Clinic

Alzheimer's & Dementia | October 9, 2013 | Volume: 9 | Issue: 4S_Part_14 | Pages: No page available

10.1016/j.jalz.2013.05.1077 Get It

P3‐212: Hippocampal subfield atrophy in the Alzheimer's Disease Neuroimaging Initiative (ADNI) Cohort: Relationships to diagnosis and memory impairment
Boddu, Mohan, West, John D. , Wan, Jing , Weiner, Michael W. , Initiative, The Alzheimer's Disease Neuroimaging, Ramanan, Vijay K. , Shen, Li , Risacher, Shannon L. , Kim, Sungeun , Wang, Yang , Crane, Paul K. , Jack, Clifford R. , Saykin, Andrew J. , Initiative, The Alzheimer's Disease Neuroimaging

Mayo Clinic

Alzheimer's & Dementia | July 19, 2012 | Volume: 8 | Issue: 4S_Part_14 | Pages: No page available

10.1016/j.jalz.2012.05.1434 Get It