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131 citation(s) found for "Allen, Mariet".

O2‐10‐04: A Regulatory Variant at the TREM Gene Cluster Associates with Decreased Alzheimer’s Disease Risk and Increased TREML1 and TREM2 Brain Gene Expression
Carrasquillo, Minerva M. , Allen, Mariet , Strickland, Samantha L. , Aryal, Shivani , Kachadoorian, Michaela, Medway, Christopher, Younkin, Curtis, Nair, Asha, Chanana, Pritha , Wang, Xue , Serie, Daniel, Nguyen, Thuy , Lincoln, Sarah, Malphrus, Kimberly G., Golde, Todd E. , Jager, Philip L. De , Asmann, Yan W. , Younkin, Steven G., Ertekin‐Taner, Nilüfer , Carrasquillo, Minerva M. , Burgess, Jeremy D. , Siuda, Joanna S. , Morgan, Kevin , Price, Nathan D. , White, Charles, Soni, Rajesh K , Crook, Julia E. , Dickson, Dennis W.

Mayo Clinic

Alzheimer's & Dementia | October 17, 2016 | Volume: 12 | Issue: 7S_Part_5 | Pages: No page available

10.1016/j.jalz.2016.06.451 Get It

IC‐P‐072: Gene Expression Of ABCA7 Dysregulated in Peripheral Blood is Associated With Decreased Metabolic Activity in Hippocampus
Kim, Sungeun , Horgousluoglu, Emrin, Apostolova, Liana G. , Lin, Kuang , Allen, Mariet , Wang, Xue , Ertekin‐Taner, Nilüfer , Petersen, Ronald , Soares, Holly , Singh, Parul , Wang, Lisu, Qi, Zhenhao, He, Aiqing, Neuhaus, Isaac , Patel, Vishal , Faber, Kelley, Simmons, Andrew , Weiner, Michael W. , Nho, Kwangsik T. , Risacher, Shannon L. , Keohane, Aoife , Lunnon, Katie , Hodges, Angela , Burgess, Jeremy D. , Foroud, Tatiana , Lovestone, Simon , Saykin, Andrew J.

Mayo Clinic

Alzheimer's & Dementia | October 17, 2016 | Volume: 12 | Issue: 7S_Part_1 | Pages: No page available

10.1016/j.jalz.2016.06.102 Get It

P4‐048: Convergent Analysis of Endophenotypes in Progressive Supranuclear Palsy
Allen, Mariet , Wang, Xue , Younkin, Curtis, Serie, Daniel, Baheti, Saurabh , Nguyen, Thuy , Lincoln, Sarah, Malphrus, Kimberly G., Carrasquillo, Minerva M. , Zou, Fanggeng, Chai, High-Seng, Schellenberg, Gerard D. , Younkin, Steven G. , Ördög, Tamás , Asmann, Yan W. , Ertekin‐Taner, Nilüfer , Sun, Zhifu , Burgess, Jeremy D. , Kouri, Naomi , Carrasquillo, Minerva M. , Murray, Melissa E. , Crook, Julia E. , Dickson, Dennis W.

Mayo Clinic

Alzheimer's & Dementia | October 17, 2016 | Volume: 12 | Issue: 7S_Part_21 | Pages: No page available

10.1016/j.jalz.2016.06.2137 Get It

F2‐01‐04: From Systems Level Transcriptomics to new Immune Targets for Alzheimer’s Disease
Golde, Todd E. , Ertekin‐Taner, Nilüfer , Chakrabarty, Paramita , Allen, Mariet , Carrasquillo, Minerva M. , Younkin, Steven G. , Levites, Yona , Funk, Corey, Heavner, Benjamen D., Logsdon, Ben , Li, Hongdong , Younkin, Curtis, Petersen, Ronald C. , Ceballos‐Diaz, Carolina, Rosario, Awilda M., Adamson, Jeniffer, Giasson, Benoit I. , Graff‐Radford, Neill R. , Yachnis, Tony, Zou, Fanggeng, Eddy, James A. , Wang, Xue , Chai, High-Seng, Serie, Daniel, Nguyen, Thuy , Lincoln, Sarah, Malphrus, Kimberly G., Bisceglio, Gina, Asmann, Yan W. , Carrasquillo, Minerva M. , Dickson, Dennis W. , Price, Nathan D. , Mangravite, Lara M. , Li, Hong-Dong, Burgess, Jeremy D. , Cruz, Pedro E. , Crook, Julia E. , Wang, Chen , Ma, Li

Mayo Clinic

Alzheimer's & Dementia | October 17, 2016 | Volume: 12 | Issue: 7S_Part_4 | Pages: No page available

10.1016/j.jalz.2016.06.383 Get It

P1‐117: Blood Gene Expression Changes Implicated in Alzheimer’s Disease
Allen, Mariet , Wang, Xue , Nguyen, Thuy , Malphrus, Kimberly G., Serie, Daniel, Strickland, Samantha L. , Lincoln, Sarah, Carrasquillo, Minerva M. , Schellenberg, Gerard D. , Lowe, Val J. , Younkin, Steven G. , Asmann, Yan W. , Petersen, Ronald C. , Ertekin‐Taner, Nilüfer , Burgess, Jeremy D. , Nho, Kwangsik T. , Carrasquillo, Minerva M. , Crook, Julia E. , Knopman, David S. , Saykin, Andrew J. , Jack, Clifford R.

Mayo Clinic

Alzheimer's & Dementia | October 17, 2016 | Volume: 12 | Issue: 7S_Part_9 | Pages: No page available

10.1016/j.jalz.2016.06.865 Get It

O2‐06‐02: Genome‐Wide Meta‐Analysis of Transcriptome Profiling Identifies Novel Dysregulated Genes Implicated in Alzheimer's Disease
Apostolova, Liana G. , Lin, Kuang, Allen, Mariet , Wang, Xue , Ertekin‐Taner, Nilüfer , Petersen, Ronald , Soares, Holly , Wang, Lisu, Qi, Zhenhao, He, Aiqing, Neuhaus, Isaac , Patel, Vishal , Faber, Kelley, Simmons, Andrew , Weiner, Michael W. , Nho, Kwangsik T. , Kim, Sungeun , Risacher, Shannon L. , Keohane, Aoife , Lunnon, Katie , Hodges, Angela , Burgess, Jeremy D. , Singh, Parul , Foroud, Tatiana , Lovestone, Simon , Saykin, Andrew J.

Mayo Clinic

Alzheimer's & Dementia | October 17, 2016 | Volume: 12 | Issue: 7S_Part_5 | Pages: No page available

10.1016/j.jalz.2016.06.425 Get It

P4‐031: Integrative Network Analysis of Multiple Alzheimer's Disease Rnaseq Studies From the Accelerating Medicine Partnership‐Alzheimer's Disease Consortium
Zhang, Bin , Komashko, Vitalina, Mostafavi, Sara , Funk, Cory C. , Allen, Mariet , Amberkar, Sandeep , Hide, Winston, Schadt, Eric , Jager, Philip L. De , Ertekin‐Taner, Nilüfer , Logsdon, Ben , Chen, Mingming , Perumal, Thanneer Malai , Hide, Winston, Friend, Stephen , Bennett, David A. , Price, Nathan D. , Mangravite, Lara M.

Mayo Clinic

Alzheimer's & Dementia | October 17, 2016 | Volume: 12 | Issue: 7S_Part_21 | Pages: No page available

10.1016/j.jalz.2016.06.2120 Get It

P3‐092: Mapping Regulatory Variants in the Alzheimer's Disease Candidate Gene ABCA7
Clement, Naomi , Medway, Christopher, Ertekin‐Taner, Nilüfer , Carrasquillo, Minerva M. , Younkin, Steven G. , Allen, Mariet , Tam, Tammie , Petersen, Ronald C. , Graff‐Radford, Neill R. , Carrasquillo, Minerva M. , Guetta‐Baranes, Tamar , Burgess, Jeremy D. , Dickson, Dennis W. , Chappell, Sally , Morgan, Kevin

Mayo Clinic

Alzheimer's & Dementia | October 17, 2016 | Volume: 12 | Issue: 7S_Part_17 | Pages: No page available

10.1016/j.jalz.2016.06.1751 Get It

P4‐027: Combing Evidence Across Multiple Cohorts for Systems‐Based Target Discovery: the AMP‐AD Knowledge Portal
Allen, Mariet , Funk, Corey, Xu, Jishu , Logsdon, Ben , Yu, Lei , Schuyler, Sarah, Friend, Stephen , Schadt, Eric , Jager, Philip L. De , Ertekin‐Taner, Nilüfer , Dang, Kristen K. , Perumal, Thanneer Malai , Wang, Minghui , Bennett, David A. , Zhang, Bin , Price, Nathan D. , Mangravite, Lara M.

Mayo Clinic

Alzheimer's & Dementia | October 17, 2016 | Volume: 12 | Issue: 7S_Part_21 | Pages: No page available

10.1016/j.jalz.2016.06.2116 Get It

MAPT haplotype H1G is associated with increased risk of dementia with Lewy bodies
Lorenzo‐Betancor, Oswaldo , Soto‐Ortolaza, Alexandra I., Walton, Ronald L., Murray, Melissa E. , Allen, Mariet , Uitti, Ryan J. , Smith, Glenn E. , Kantarci, Kejal , Lowe, Val J. , Jack, Clifford R. , Ertekin‐Taner, Nilüfer , Hassan, Anhar , Savica, Rodolfo , Petersen, Ronald C. , Parisi, Joseph E., Maraganore, Demetrius M. , Graff‐Radford, Neill R. , Ferman, Tanis J. , Ross, Owen A. , Soto‐Beasley, Alexandra I. , Labbé, Catherine, Lorenzo-Betancor, Oswaldo, Soto-Ortolaza, Alexandra I., Labbé, Catherine , Heckman, Michael G. , Wszołek, Zbigniew K. , Knopman, David S. , Boeve, Bradley F. , Dickson, Dennis W. , Jack, Clifford R , Ross, Owen A , Kantarci, Kejal , Murray, Melissa E , Ferman, Tanis J , Beasley, Alexandra I

Mayo Clinic

Alzheimer's & Dementia | June 8, 2016 | Volume: 12 | Issue: 12 | Pages: 1297-1304

10.1016/j.jalz.2016.05.002 | PMID 27287057 Get It

Abstract Introduction The MAPT H1 haplotype has been associated with several neurodegenerative diseases. We were interested in exploring the role of MAPT haplotypic variation in risk of dementia with Lewy bodies (DLB). Method We genotyped six MAPT haplotype tagging SNPs and screened 431 clinical DLB cases, 347 pathologically defined high‐likelihood DLB cases, and 1049 controls. Result We performed haplotypic association tests and detected an association with the protective H2 haplotype in our combined series (odds ratio [OR] = 0.75). We fine‐mapped the locus and identified a relatively rare haplotype, H1G, that is associated with an increased risk of DLB (OR = 3.30, P = .0017). This association was replicated in our pathologically defined series (OR = 2.26, P = .035). Discussion These results support a role for H1 and specifically H1G in susceptibility to DLB. However, the exact functional variant at the locus is still unknown, and additional studies are warranted to fully explain genetic risk of DLB at the MAPT locus.