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47 citation(s) found for "Whyte, MP".

Strengthening Physical Medicine and Rehabilitation Departmental Research: Insights From the Association of Academic Physiatrists Research Consulting Program
Wang, Qing Mei , Lencioni, Stephen, Huber, Justin , Rizzo, John‐Ross , Scholten, Paul , Swanson, Randel L. , Schnappinger, Amy, Arnold, W David , Annaswamy, Thiru M. , Bean, Allison , Kumbhare, Dinesh Arun , Li, Sheng , Paganoni, Sabrina , Suskauer, Stacy J. , Whyte, John , Arnold, W. David

Mayo Clinic

American Journal of Physical Medicine & Rehabilitation | October 9, 2025 | Volume: 104 | Issue: 12 | Pages: 1186-1189

10.1097/phm.0000000000002769 | PMID 41065593 Get It

Abstract Clinical and translational research is important for health care and the growth of medical specialties. Physical medicine and rehabilitation offers many opportunities for research, but research growth in physical medicine and rehabilitation is lacking, and research resources and productivity vary across academic physical medicine and rehabilitation departments across North America. The Physiatric Research Consulting Program was developed by the Association of Academic Physiatrists to provide customized recommendations to enhance research capacity and productivity in physical medicine and rehabilitation departments. This report outlines the three components of the Physiatric Research Consulting Program, including a previsit needs assessment, an in-person visit, and a postvisit follow-up final report. The report also provides a qualitative assessment of the impact of the Physiatric Research Consulting Program, with general themes of feedback, site visit evaluations, and final report evaluations. The Physiatric Research Consulting Program was found to be valuable in identifying gaps and needs for physical medicine and rehabilitation departments, providing outside perspectives, and energizing faculty toward research growth in their departments.
A bioadhesive pacing lead for atraumatic cardiac monitoring and stimulation in rodent and porcine models
Deng, Jue , Wu, Jingjing , Sarrafian, Tiffany L. , Varela, Claudia E., Roche, Ellen T. , Griffiths, Leigh G. , Yuk, Hyunwoo , Chen, Xiaoyu , Sarrafian, Tiffany L , Varela, Claudia E , Whyte, William , Guo, Chuan Fei , Roche, Ellen T , Griffiths, Leigh G , Nabzdyk, Christoph , Zhao, Xuanhe , Chen, Xiaoyu , Nabzdyk, Christoph S. , Zhao, Xuanhe

Mayo Clinic

Science Translational Medicine | June 19, 2024 | Volume: 16 | Issue: 752 | Pages: No page available

10.1126/scitranslmed.ado9003 | PMID 38896601 Get It

Current clinically used electronic implants, including cardiac pacing leads for epicardial monitoring and stimulation of the heart, rely on surgical suturing or direct insertion of electrodes to the heart tissue. These approaches can cause tissue trauma during the implantation and retrieval of the pacing leads, with the potential for bleeding, tissue damage, and device failure. Here, we report a bioadhesive pacing lead that can directly interface with cardiac tissue through physical and covalent interactions to support minimally invasive adhesive implantation and gentle on-demand removal of the device with a detachment solution. We developed 3D-printable bioadhesive materials for customized fabrication of the device by graft-polymerizing polyacrylic acid on hydrophilic polyurethane and mixing with poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) to obtain electrical conductivity. The bioadhesive construct exhibited mechanical properties similar to cardiac tissue and strong tissue adhesion, supporting stable electrical interfacing. Infusion of a detachment solution to cleave physical and covalent cross-links between the adhesive interface and the tissue allowed retrieval of the bioadhesive pacing leads in rat and porcine models without apparent tissue damage. Continuous and reliable cardiac monitoring and pacing of rodent and porcine hearts were demonstrated for 2 weeks with consistent capture threshold and sensing amplitude, in contrast to a commercially available alternative. Pacing and continuous telemetric monitoring were achieved in a porcine model. These findings may offer a promising platform for adhesive bioelectronic devices for cardiac monitoring and treatment.
Rehabilitation Treatment Specification System: Content and Criterion Validity Across Evidence-Based Voice Therapies for Muscle Tension Dysphonia
Stan, Jarrad H. Van , Roy, Nelson , Stemple, Joseph C., Gartner-Schmidt, Jaqueline, Gillespie, Amanda I. , Duffy, Joseph R. , Turkstra, Lyn S. , Van Stan, Jarrad H , Duffy, Joseph R , Turkstra, Lyn , Roy, Nelson , Whyte, John

Mayo Clinic

American Journal of Speech-Language Pathology | April 10, 2024 | Volume: 33 | Issue: 4 | Pages: 1774-1791

10.1044/2024_ajslp-23-00362 | PMID 38597797 Get It

Purpose: Systematically improving voice therapy outcomes is challenging as the clinician actions (i.e., active ingredients) responsible for improved patient functioning (i.e., targets) are relatively unknown. The theory-driven Rehabilitation Treatment Specification System (RTSS) and standard, voice-specific terminology based on the RTSS (RTSS-Voice) may help address this problem. This qualitative study evaluated if the RTSS and RTSS-Voice can describe four evidence-based voice therapies for muscle tension dysphonia without missing critical aspects (content validity) and identify commonalities and differences across them (criterion validity). Method: Qualitative interviews were completed between the clinicians (protocol experts) who developed and/or popularized the vocal function exercises, laryngeal reposturing, circumlaryngeal massage, and conversation training therapies as well as RTSS experts to produce RTSS specifications that met two consensus criteria: (a) The protocol expert agreed that the specification represented their treatment theory, and (b) the RTSS experts agreed that the specifications correctly adhered to both the RTSS framework and the RTSS-Voice's standard terminology. Results: The RTSS and RTSS-Voice comprehensively described voice therapy variations across and within the four diverse treatment programs, needing only the addition of one new target: overall auditory-perceptual severity. Conclusions: The RTSS and RTSS-Voice exhibited strong content validity. The standard RTSS-Voice terminology helped identify, for the first time, commonalities and differences in treatment ingredients, targets, and mechanisms of action across four treatments developed for the same patient population. In the long term, the RTSS and RTSS-Voice could provide the framework for an ever-growing collection of clinically meaningful and evidence-based therapy algorithms with potential to improve research, education, and clinical care. Supplemental Material: https://doi.org/10.23641/asha.25537624
A survey of practice in the anesthetic management of adolescent idiopathic scoliosis spine fusion by the North American Pediatric Spine Anesthesiologists Collaborative
Gilbertson, Laura E. , Muhly, Wallis T. , Montana, Michael C. , Chidambaran, Vidya , Sadacharam, Kesavan , Wilder, Robert T., Whyte, Simon D. , Hifko, Alan, Frankville, David D., Investigators, North American Pediatric Spine Anesthesiologists, Whyte, Simon D , DiCindio, Sabina , Sponseller, Paul D. , Investigators, North American Pediatric Spine Anesthesiologists

Mayo Clinic

Pediatric Anesthesia | April 5, 2024 | Volume: 34 | Issue: 7 | Pages: 645-653

10.1111/pan.14895 | PMID 38578166 Get It

AbstractBackgroundAdolescent Idiopathic Scoliosis (AIS) affects 2%–4% of the general pediatric population. While surgical correction remains one of the most common orthopedic procedures performed in pediatrics, limited consensus exists on the perioperative anesthetic management.AimsTo examine the current state of anesthetic management of typical AIS spine fusions at institutions which have a dedicated pediatric orthopedic spine surgeon.MethodsA web‐based survey was sent to all members of the North American Pediatric Spine Anesthesiologists (NAPSA) Collaborative. This group included 34 anesthesiologists at 19 different institutions, each of whom has a Harms Study Group surgeon performing spine fusions at their hospital.ResultsThirty‐one of 34 (91.2%) anesthesiologists completed the survey, with a missing response rate from 0% to 16.1% depending on the question. Most anesthesia practices (77.4%; 95% confidence interval [CI], 67.7–93.4) do not have patients come for a preoperative visit prior to the day of surgery. Intravenous induction was the preferred method (74.2%; 95% CI 61.3–89.9), with the majority utilizing two peripheral IVs (93.5%; 95% CI 90.3–100) and an arterial line (100%; 95% CI 88.8–100). Paralytic administration for intubation and/or exposure was divided (51.6% rocuronium/vecuronium, 45.2% no paralytic, and 3.2% succinylcholine) amongst respondents. While tranexamic acid was consistently utilized for reducing blood loss, dosing regimens varied. When faced with neuromonitoring signal issues, 67.7% employ a formal protocol. Most anesthesiologists (93.5%; 95% CI 78.6–99.2) extubate immediately postoperatively with patients admitted to an inpatient floor bed (77.4%; 95% CI 67.7–93.3).ConclusionMost anesthesiologists (87.1%; 95% CI 80.6–99.9) report the use of some form of an anesthesia‐based protocol for AIS fusions, but our survey results show there is considerable variation in all aspects of perioperative care. Areas of agreement on management comprise the typical vascular access required, utilization of tranexamic acid, immediate extubation, and disposition to a floor bed. By recognizing the diversity of anesthetic care, we can develop areas of research and improve the perioperative management of AIS.
NeurologicManifestations of Neglected Tropical Diseases (P4.295)
Berkowitz, Aaron L., Headley-Whyte, E. Tessa, Raibagkar, Pooja , Pritt, Bobbi S. , Mateen, Farrah J.

Mayo Clinic

Neurology | December 7, 2023 | Volume: 82 | Issue: 10_supplement | Pages: No page available

10.1212/wnl.82.10_supplement.p4.295 Get It

Pulmonary Vessel Volume Using a Connected Graph-Based Approach in IPF and Healthy Controls
John, Joyce , Levin, D.L., Karworski, R., King, C., Wilsher, Margaret , Whyte, K., Milne, D. G., Clark, Alys Rachel , Kumar, Haribalan , Burrowes, Kelly , Bartholmai, Brian J. , Tawhai, Merryn Howatson

Mayo Clinic

B22. EMERGING MANAGEMENT OF FIBROTIC ILDs | May 2, 2022 | Volume: No volume available | Issue: No issue available | Pages: A2425-A2425

10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2425 Get It

Lung Shape in IPF Is Different from Healthy Controls, and Is Associated with Extent of Fibrosis
John, Joyce , Karworski, R., Levin, D.L., King, C., Wilsher, Margaret , Whyte, K., Milne, D. G., Clark, Alys Rachel , Kumar, Haribalan , Burrowes, Kelly , Bartholmai, Brian J. , Tawhai, Merryn Howatson

Mayo Clinic

B36. SPECTRUM OF FIBROTIC INTERSTITIAL LUNG DISEASES | May 2, 2022 | Volume: No volume available | Issue: No issue available | Pages: A2732-A2732

10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2732 Get It

Accuracy of Simulated Research Tasks by Community Hospitals Participating in a Multicenter Telemedicine Trial
Fang, Jennifer L. , Whyte, Hilary, Umoren, Rachel , Limjoco, Jamie , Yankanah, Rosanna, McCoy, Mike, Lo, Mark D., Demaerschalk, Bart M. , Demaerschalk, Bart M , Makkar, Abhishek , Herrin, Jeph

Mayo Clinic

Telemedicine and e-Health | February 15, 2022 | Volume: 28 | Issue: 10 | Pages: 1489-1495

10.1089/tmj.2021.0574 | PMID 35167373 Get It

Background/Aims: Clinical trials evaluating facility-to-facility telemedicine may include sites that have limited research experience. For the trial to be successful, these sites must correctly perform research-related tasks. This study aimed to determine whether health care professionals at community hospitals could accurately identify simulated study eligible patients and submit data to a research coordinating center. Methods: Twenty-seven community hospitals in the United States and Canada participated in this study. An electronic survey was sent to one designated health care professional at each site. The survey included a description of trial eligibility criteria and five written neonatal resuscitation scenarios. For each scenario, the participant determined whether the neonate was study eligible. One scenario required participants to submit 14 data elements to the coordinating center. Accuracy of study eligibility and data submission was summarized using standard descriptive statistics. Results: The survey response rate was 100% (27/27). Overall accuracy in determining study eligibility was 89% (120/135), and accuracy varied across the five scenarios (range 82–93%). Overall accuracy of data submission was 92% (310/336). Data were >95% accurate for 9 of the 14 data elements, with 100% accuracy achieved for 6 data elements. These results were used to clarify eligibility criteria, inform database design, and improve training materials for the subsequent clinical trial. Conclusions: Health care professionals at community hospitals accurately determined trial eligibility and submitted study data based on written clinical scenarios. Research teams conducting telemedicine trials with community hospitals should consider completing pre-trial simulation activities to identify opportunities for improving trial processes and materials.
Provider Perspectives on the Acceptability, Appropriateness, and Feasibility of Teleneonatology
Fang, Jennifer L. , Umoren, Rachel , Whyte, Hilary, Yankanah, Rosanna, McCoy, Mike, Lo, Mark D., Colby, Christopher E. , Limjoco, Jamie , Makkar, Abhishek , Herrin, Jeph , Jacobson, Robert M. , Demaerschalk, Bart M.

Mayo Clinic

American Journal of Perinatology | October 19, 2021 | Volume: No volume available | Issue: No issue available | Pages: No page available

10.1055/s-0041-1736587 Get It

Objective We aimed to measure provider perspectives on the acceptability, appropriateness, and feasibility of teleneonatology in neonatal intensive care units (NICUs) and community hospitals. Study Design Providers from five academic tertiary NICUs and 27 community hospitals were surveyed using validated implementation measures to assess the acceptability, appropriateness, and feasibility of teleneonatology. For each of the 12 statements, scale values ranged from 1 to 5 (1 = strongly disagree; 5 = strongly agree), with higher scores indicating greater positive perceptions. Survey results were summarized, and differences across respondents assessed using generalized linear models. Results The survey response rate was 56% (203/365). Respondents found teleneonatology to be acceptable, appropriate, and feasible. The percent of respondents who agreed with each of the twelve statements ranged from 88.6 to 99.0%, with mean scores of 4.4 to 4.7 and median scores of 4.0 to 5.0. There was no difference in the acceptability, appropriateness, and feasibility of teleneonatology when analyzed by professional role, years of experience in neonatal care, or years of teleneonatology experience. Respondents from Level I well newborn nurseries had greater positive perceptions of teleneonatology than those from Level II special care nurseries. Conclusion Providers in tertiary NICUs and community hospitals perceive teleneonatology to be highly acceptable, appropriate, and feasible for their practices. The wide acceptance by providers of all roles and levels of experience likely demonstrates a broad receptiveness to telemedicine as a tool to deliver neonatal care, particularly in rural communities where specialists are unavailable. Key Points
Provider Perspectives on the Acceptability, Appropriateness, and Feasibility of Teleneonatology
Fang, Jennifer L. , Umoren, Rachel , Whyte, Hilary, Limjoco, Jamie , Yankanah, Rosanna, McCoy, Mike, Lo, Mark D., Colby, Christopher E. , Jacobson, Robert M. , Makkar, Abhishek , Herrin, Jeph , Demaerschalk, Bart M.

Mayo Clinic

American Journal of Perinatology | September 28, 2021 | Volume: 40 | Issue: 14 | Pages: 1521-1528

10.1055/a-1656-6363 | PMID 34583392 Get It

Objective We aimed to measure provider perspectives on the acceptability, appropriateness, and feasibility of teleneonatology in neonatal intensive care units (NICUs) and community hospitals. Study Design Providers from five academic tertiary NICUs and 27 community hospitals were surveyed using validated implementation measures to assess the acceptability, appropriateness, and feasibility of teleneonatology. For each of the 12 statements, scale values ranged from 1 to 5 (1 = strongly disagree; 5 = strongly agree), with higher scores indicating greater positive perceptions. Survey results were summarized, and differences across respondents assessed using generalized linear models. Results The survey response rate was 56% (203/365). Respondents found teleneonatology to be acceptable, appropriate, and feasible. The percent of respondents who agreed with each of the twelve statements ranged from 88.6 to 99.0%, with mean scores of 4.4 to 4.7 and median scores of 4.0 to 5.0. There was no difference in the acceptability, appropriateness, and feasibility of teleneonatology when analyzed by professional role, years of experience in neonatal care, or years of teleneonatology experience. Respondents from Level I well newborn nurseries had greater positive perceptions of teleneonatology than those from Level II special care nurseries. Conclusion Providers in tertiary NICUs and community hospitals perceive teleneonatology to be highly acceptable, appropriate, and feasible for their practices. The wide acceptance by providers of all roles and levels of experience likely demonstrates a broad receptiveness to telemedicine as a tool to deliver neonatal care, particularly in rural communities where specialists are unavailable. Key Points