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55 citation(s) found for "Rizzo, Marco".

Metacarpophalangeal Arthroplasty: A 14-Year Nationwide Analysis of Trends and Acute Perioperative Outcomes in Rheumatoid Arthritis and Osteoarthritis
Schluttenhofer, Adam , Rizzo, Marco

Mayo Clinic

HAND | October 8, 2026 | Volume: No volume available | Issue: No issue available | Pages: No page available

10.1177/15589447261485505 | PMID 42847659 Get It

Background: Metacarpophalangeal (MCP) arthroplasty is an established surgical option for end-stage MCP arthritis. We analyzed trends in case volumes and 30-day perioperative outcomes after MCP arthroplasty performed for rheumatoid arthritis (RA) and osteoarthritis (OA). Methods: We used the National Surgical Quality Improvement Program database to identify all MCP arthroplasties performed for RA (n = 216) or OA (n = 452) between 2010 and 2023. Bivariate analysis was used to compare patient demographics, operative characteristics, and 30-day outcomes. We analyzed temporal trends in case volumes using Poisson regression models and trends in patient characteristics using linear regression. Results: Patients with RA were more likely to be female (85% vs 54%) and have a history of smoking (22% vs 10%) and chronic steroid use (58% vs 4%). Patients with OA had more prevalent comorbidities including obesity, diabetes, and hypertension. Patients with RA more frequently required multi-joint replacement, concomitant soft tissue balancing procedures, plastic surgery involvement, and inpatient admission. The annual case volume for OA increased at +5.9% per year ( P < .001), whereas the volume for RA remained steady. The outpatient case volume grew at a rate of +4.6% per year ( P < .001). Both groups had similarly low rates of 30-day complications (0.9% RA, 1.8% OA), readmission (0.5% RA, 1.5% OA), and reoperation (0% RA, 0.9% OA). Conclusions: Despite distinct patient profiles and operative complexity, both OA and RA patients experience low rates of perioperative adverse events after MCP arthroplasty. Osteoarthritis is a growing indication for this procedure, which is increasingly being performed in the outpatient setting.
Humility: The Essential Virtue Enhancing Patient Care, Education, Research, and Innovation
Rizzo, Marco, Lin, Ines, Murray, Peter, Sotereanos, Dean, Stern, Peter, Rizzo, Marco , Lin, Ines C. , Sotereanos, Dean G., Stern, Peter J.

Mayo Clinic

Journal of Bone and Joint Surgery | May 26, 2026 | Volume: 108 | Issue: 15 | Pages: 1149-1152

10.2106/jbjs.26.00381 | PMID 42189960 Get It

The word humility is derived from the Latin word humus, meaning “ground” or “soil.” Romans equated humility with being grounded. Perhaps because it contradicts our natural tendencies toward self-preservation, humility remains an often misunderstood and underappreciated virtue. It is foreign to many, especially in today’s society, which is so focused on self-promotion. However, it is truly one of the most important and powerful virtues that a person can possess and practice. Humility is a just assessment of ourselves and the world around us. It is not thinking less of oneself; rather, it is actually thinking less about oneself. In looking beyond ourselves, we can obtain an honest estimate of our limitations and what is needed to remain patient-centered. In approaching our profession with humility, we more closely honor the privileges of caring for patients, teaching others, innovating, and advancing science. The aim of this article is to show how humility nurtures our development in all aspects of medicine. A humble clinician maintains a steadfast focus on their patient, a humble educator emphasizes the learner, a humble researcher respects science through their honesty and integrity, and a humble innovator does not let pride blind them, recognizing that innovation without humility is doomed to fail. In addition to being a superpower in medicine, humility blesses us with the wisdom and gratitude that come from experiencing, living for, and working for something bigger than ourselves. Gratitude has been considered the father of all virtues, and our ability to be truly grateful requires a core of humility.
Silicone Metacarpophalangeal Arthroplasty: A Matched Cohort of Osteoarthritis and Rheumatoid Arthritis Patients
Postal, Zoe, Schluttenhofer, Adam , Bankes, Audrey, Rizzo, Marco , Schluttenhofer, Adam , Bankes, Audrey

Mayo Clinic

HAND | April 21, 2026 | Volume: No volume available | Issue: No issue available | Pages: No page available

10.1177/15589447261437819 | PMID 42012013 Get It

Background: Little is known about how silicone metacarpophalangeal (MCP) arthroplasty outcomes compare between rheumatoid arthritis (RA) and osteoarthritis (OA) patients. Methods: Using our single institutional data from 2000 to 2022, we propensity matched 46 primary silicone MCP arthroplasties in 33 OA patients 1:2 to 92 arthroplasties in 54 RA patients based on age, sex, body mass index, operative digit, and if the surgery was on the dominant hand. We used Kaplan-Meier estimates and cluster-robust Cox proportional hazard models to compare survival free from revision, all-cause reoperation, and development of coronal plane deviation >10°. Results: There was comparable 10-year survival free of revision (94% OA, 91% RA) and all-cause reoperation (91% OA, 87% RA), with no difference in risk for each outcome between groups. Revision in OA patients occurred early (mean 0.6 years) for recurrent deformity (n = 2) and periprosthetic joint infection (n = 1). Revision in the RA cohort occurred later (mean 6.3 years postoperatively) for recurrent deformity (n = 3) and dislocation (n = 1). Osteoarthritis patients had less coronal plane deviation at the final radiographic follow-up (6.5° vs 16.2°, P < .001), higher 10-year survival free from coronal deviation > 10° (79% vs 17%), and lower risk of progressive coronal deformity (hazard ratio 0.15, P < .001). Conclusions: Silicone MCP arthroplasty remains a durable option with low reoperation rates for RA and OA. Osteoarthritis patients experience less coronal deviation and late reoperation for deformity than RA patients, likely due to their more robust soft-tissue stabilizers and noninflammatory disease process.
Effect of Anti-Cyclic Citrullinated Peptide Antibody Serostatus on Outcomes of Silicone Metacarpophalangeal Arthroplasty in Patients With Rheumatoid Arthritis
Schluttenhofer, Adam T, Postal, Zoe, Bankes, A., Rizzo, Marco, Schluttenhofer, Adam , Schluttenhofer, Adam , Bankes, Audrey, Schaffer, Daniel, Rizzo, Marco , Bankes, Audrey , Schaffer, Daniel

Mayo Clinic

HAND | March 30, 2026 | Volume: No volume available | Issue: No issue available | Pages: No page available

10.1177/15589447261430933 | PMID 41905894 Get It

Background: Anti-cyclic citrullinated peptide antibodies (ACPAs) are associated with more aggressive rheumatoid arthritis disease. We aimed to determine the effect of ACPA serostatus on survival free from revision, all-cause reoperation, and recurrence of coronal plane deformity in patients with rheumatoid arthritis (RA) undergoing silicone metacarpophalangeal (MCP) arthroplasty. Methods: We retrospectively identified silicone MCP arthroplasties performed in patients with RA with known ACPA serostatus from 2000 to 2022. Kaplan-Meier estimates were used to report survival free from revision, all-cause reoperation, and recurrence of coronal plane deviation >10° on postoperative radiographs. We analyzed ACPA serostatus as a risk factor for these endpoints using cluster-robust Cox proportional hazard models, adjusting for patient sex. Results: We included 133 joints in 39 ACPA seropositive patients (9.0 years mean follow-up) and 63 joints in 21 ACPA seronegative patients (5.7 years mean follow-up). Survival free from revision, all-cause reoperation, and recurrent coronal deformity was higher in seropositive patients than in seronegative patients. Anti-cyclic citrullinated peptide antibody seropositivity was significantly associated with lower risk for revision (hazard ratio [HR] = 0.16), all-cause reoperation (HR = 0.20), and recurrent coronal plane deviation >10° (HR = 0.28). Seropositive patients had longer average time to recurrent coronal deviation >10° (3.5 years vs 1.3 years) and less coronal deviation at final radiographic follow-up (15.9° vs 21.5°). Conclusions: Anti-cyclic citrullinated peptide antibody seropositivity is associated with improved silicone MCP implant survivorship and lower risk of recurrent coronal plane deformity in patients with rheumatoid arthritis. More work is needed to better understand the biologic basis of these findings.
The Complex Relationship Between Body Mass Index and Risk for Adverse Outcomes Following Pyrocarbon Metacarpophalangeal Arthroplasty for Rheumatoid Arthritis
Schluttenhofer, Adam T, Rizzo, Marco, Schluttenhofer, Adam , Schluttenhofer, Adam , Rizzo, Marco

Mayo Clinic

HAND | February 27, 2026 | Volume: No volume available | Issue: No issue available | Pages: No page available

10.1177/15589447261416989 | PMID 41748130 Get It

Background: Use of pyrocarbon metacarpophalangeal (MCP) implants in rheumatoid arthritis (RA) patients has been associated with high rates of complications and reoperations. To date, few patient-specific prognostic factors have been identified. This study investigated body mass index (BMI) as a risk factor for RA patients undergoing pyrocarbon MCP arthroplasty. Methods: We included 148 joints (51 patients) that underwent pyrocarbon MCP implantation at our institution from 2000 to 2022. We analyzed survival free from revision, reoperation, and development of postoperative complications using cluster-robust Cox proportional hazard models with restricted cubic splines to plot non linear relationships. Secondarily, we compared survival above and below the World Health Organization cutoff for obesity of ≥ 30 kg/m 2 , adjusting for patient age and sex. Results: The relationship between BMI and risk for complications and revisions was J-shaped, with an increase in risk beyond 29 kg/m 2 . The relationship between BMI and late reoperations was U-shaped, with patients above 27.3 kg/m 2 and below 23.2 kg/m 2 at elevated risk. A BMI ≥ 30 kg/m 2 was associated with a 7.9-times increased risk for revision, 8.3-times increased risk for late reoperations, and 3.7-times increased risk for postoperative complications. Body mass index did not significantly influence risk for early reoperation. Conclusions: Body mass index was associated with pyrocarbon MCP implant failure in a non linear fashion, with overweight patients at risk for complications leading to revisions and late reoperations. Underweight patients may be at increased risk for late reoperations. These findings should inform patient and implant selection and help guide counseling for postoperative expectations.
The Hidden Power of Humility: Elevating Patient and Provider Experience Through Clinician Self-Awareness and Patient-Centered Care
Rizzo, Marco, Hunderfund, Andrea Leep, Pestorious, Ann, Welch, Thomas J, Rizzo, Marco , Hunderfund, Andrea N. Leep , Welch, Thomas

Mayo Clinic

Journal of Patient Experience | January 20, 2026 | Volume: 13 | Issue: No issue available | Pages: No page available

10.1177/23743735261415652 | PMID 41573242 Get It

Humility is one of the most powerful and sometimes least understood virtues we can possess. It is often misinterpreted as a sign of weakness, especially today, where self-promotion is encouraged and celebrated. Many people view humility as “thinking less of ourselves.” In truth, humility is not thinking less of oneself; rather it is appropriately thinking less about oneself. Our ability as caregivers in putting the needs of the patient at the center of all we do is enhanced through our humility. A steady focus on the needs of the patient helps us gain an honest assessment of both our strengths and limitations. Studies have shown that patient outcomes and experiences are strongly associated with provider humility. This article aims to shine a light on the power of humility and its impact on patient experience, psychological and cultural safety, and the provider-patient relationship.
Very Low Preoperative Grip Strength Associated With Poor Pyrocarbon Metacarpophalangeal Implant Survivorship in Rheumatoid Arthritis
Schluttenhofer, Adam T, Yonkman, A M , Tom, Andy, Mundi, Manpreet S., Rizzo, Marco, Schluttenhofer, Adam , Schluttenhofer, Adam , Yonkman, Alex, Rizzo, Marco , Mundi, Manpreet S.

Mayo Clinic

HAND | January 19, 2026 | Volume: No volume available | Issue: No issue available | Pages: No page available

10.1177/15589447251411543 | PMID 41552940 Get It

Background: Pyrocarbon metacarpophalangeal (MCP) arthroplasty is associated with high rates of recurrent deformity and reoperation in patients with rheumatoid arthritis (RA). We sought to determine the impact of preoperative hand grip strength (HGS) on implant survivorship in these patients. Methods: We included primary pyrocarbon MCP arthroplasties in patients with RA at our single institution from 2000 to 2022. Cox proportional hazard models with restricted cubic splines were used to model the continuous relationship between HGS and hazard for revision, all-cause reoperation, and development of any complication, accounting for multiple joints per patient and adjusting for sex. Kaplan-Meier estimates were used to report survivorship at 2, 5, and 10 years. Results: We included 75 joints in 27 patients with an average preoperative HGS of 8.6 kg (11.1 years of follow-up). There were 16 (21%) total revisions, most commonly for recurrent deformity, along with 8 nonrevision reoperations, most commonly for tendon/ligamentous repair. There was a significant, J-shaped relationship between HGS and hazard for revision ( P = .001) and all-cause reoperation ( P < .001). Patients with HGS below 5.5 and 5.3 kg had an increased risk for revision (hazard ratio [HR]: 13.5) and all-cause reoperation (HR: 9.8) compared with patients with sufficiently high HGS. The 10-year revision survival was 93% in patients with HGS >5.5 kg and 63% in patients ≤5.5 kg. Hand grip strength did not significantly affect hazard for developing a first complication. Conclusion: Very low preoperative HGS is associated with worsened implant survivorship following pyrocarbon MCP arthroplasty in patients with RA.
Retrospective Review of Pyrocarbon Hemiarthroplasty for Carpometacarpal Arthritis: An Examination of Long-Term Outcomes and Complications
Rode, Matthew M. , Mullen, Barbara , Schrader, Samuel N., Rizzo, Marco , Moran, Steven L. , Mullen, Barbara L , Rode, Matthew

Mayo Clinic

Journal of Wrist Surgery | September 29, 2025 | Volume: No volume available | Issue: No issue available | Pages: No page available

10.1055/a-2698-9954 Get It

AbstractThumb carpometacarpal (CMC) arthritis is a common and sometimes debilitating condition with a variety of surgical treatments. Pyrocarbon thumb CMC hemiarthroplasty is one option, which has demonstrated promise; however, no long-term outcomes have been reported.We performed a retrospective institutional review of 106 primary thumb CMC pyrocarbon hemiarthroplasties with a minimum of 1 year, median 6.1-year follow-up. We analyzed rates of pain relief, reoperation, and implant failure as well as biomechanical, radiographic, and patient-reported outcomes.Pain was significantly decreased after surgery. Radial and palmar abduction were modestly improved postoperatively (increased from 40–50 degrees). Implants showed high rates of radiographic osteolysis (53%) and subsidence (44%). Two-, 5-, and 10-year rates of reoperation (18, 21, 21%) and implant removal (15, 19, and 19%), respectively.Pyrocarbon thumb CMC hemiarthroplasty provides high rates of pain relief and preservation of pinch and grip strength. Patients had modest improvement in radial and palmar abduction; however, hemiarthroplasty was associated with moderate rates of reoperation and implant revision.Therapy Level IV.
Flexor Pollicis Longus Palsy Following Both-Bone Forearm Fracture Fixation: A Case-Based and Cadaveric Evaluation
Strother, Courtney Carlson , Boe, Chelsea C., Trentadue, Taylor P. , Rizzo, Marco , Carlson Strother, Courtney , Trentadue, Taylor P , Rizzo, Marco , Pulos, Nicholas

Mayo Clinic

HAND | August 23, 2025 | Volume: No volume available | Issue: No issue available | Pages: No page available

10.1177/15589447251366455 | PMID 40847804 Get It

Background: Flexor pollicis longus (FPL) palsy following both-bone forearm fracture (BBFF) is a rare complication. Methods: A retrospective review of acute BBFF treated with open reduction internal fixation by a single surgeon from 2005 to 2023 was performed. Injury and surgical characteristics of patients with documented FPL palsy were reviewed. In addition, 10 cadaveric dissections were performed to evaluate the anatomy of the anterior interosseous nerve (AIN) and its branches. The distance of these branches from palpable elbow landmarks and variability in branching pattern were evaluated. Results: Twenty-nine patients underwent surgery for acute BBFF. Of these, 5 (17%) had evidence of an FPL palsy either at the time of injury presentation (n = 2) or immediately following surgery (n = 3). All patients with FPL palsy sustained fractures in the middle one-third of the radius. All palsies resolved after an average of 33 days of observation. In cadaveric dissections, the average distance from the lateral epicondyle to the AIN takeoff and branch to the FPL was 5.5 and 7.6 cm, respectively. The AIN takeoff and branch to the FPL were never less than 4 and 7 cm from the lateral epicondyle, respectively. Conclusion: Flexor pollicis longus palsy following BBFF can occur at the time of injury or following surgery. All FPL palsies involved midshaft radial fractures and were likely neurapraxia. The etiology of FPL palsy remains unclear, but cadaveric dissection suggests the FPL motor branch may be at risk from mid-to-proximal radius fracture fragments or excessive traction during surgery.
A Novel Technique for Collateral Ligament Reconstruction at the Proximal Interphalangeal Joint
Tagliero, Lauren E., Sarcon, Aida K. , Wu, Kitty Y. , Rizzo, Marco , Sarcon, Aida, Tagliero, Lauren E.

Mayo Clinic

Techniques in Hand & Upper Extremity Surgery | May 19, 2025 | Volume: No volume available | Issue: No issue available | Pages: No page available

10.1097/bth.0000000000000517 | PMID 40384492 Get It

Chronic proximal interphalangeal (PIP) joint instability is a rare and difficult problem to treat, with the main options including collateral ligament reconstruction and joint arthrodesis. To date, there are minimal described techniques for collateral ligament reconstruction. We describe a novel technique utilizing a slip of the flexor digitorum superficialis (FDS), harvested through a single minimal incision. This technique can be used for collateral ligament reconstruction with multiple applications, including chronic recurrent PIP joint dislocations and instability during PIP joint arthroplasty.