Practical Approach to Processing Osteosarcomas in the Surgical Pathology Laboratory
Wold, Lester E.
Pediatric and Developmental Pathology | July 25, 2002 | Volume: 1 | Issue: 5 | Pages: 449-454
10.1007/s100249900062
| PMID 9688771
The pathologic assessment of definitive surgical specimens in patients treated for osteosarcoma can be rapidly accomplished using a few pieces of special equipment. Rapid decalcification with formic acid–formalin and routine tissue processing allow the histology laboratory to rapidly prepare histologic slides for pathologic evaluation. A simple qualitative assessment of tumor response to chemotherapy allows the pathologist to classify the tumor response rapidly and reproducibly, and a simple report format allows for unambiguous communication with the patient and physician.