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TNB-738, a biparatopic antibody, boosts intracellular NAD+ by inhibiting CD38 ecto-enzyme activity

mAbs | July 22, 2022 | Volume: 14 | Issue: 1 | Pages: No page available

10.1080/19420862.2022.2095949 | PMID 35867844

Phase 1, open-label, dose-escalation and expansion study of ABT-165, a dual variable domain immunoglobulin (DVD-Ig) targeting both DLL4 and VEGF, in patients (pts) with advanced solid tumors.

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