Citations 4

Navigating the Landscape of Translational Geroscience in Canada: A Comprehensive Evaluation of Current Progress and Future Directions

The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences | March 15, 2024 | Volume: 79 | Issue: 7 | Pages: No page available

10.1093/gerona/glae069 | PMID 38486371

Abstract The inaugural Canadian Conferences on Translational Geroscience were held as 2 complementary sessions in October and November 2023. The conferences explored the profound interplay between the biology of aging, social determinants of health, the potential societal impact of geroscience, and the maintenance of health in aging individuals. Although topics such as cellular senescence, molecular and genetic determinants of aging, and prevention of chronic disease were addressed, the conferences went on to emphasize practical applications for enhancing older people’s quality of life. This article summarizes the proceeding and underscores the synergy between clinical and fundamental studies. Future directions highlight national and global collaborations and the crucial integration of early-career investigators. This work charts a course for a national framework for continued innovation and advancement in translational geroscience in Canada.
Corrigendum to: Report: NIA Workshop on Measures of Physiologic Resiliencies in Human Aging

The Journals of Gerontology: Series A | May 18, 2018 | Volume: 73 | Issue: 7 | Pages: 995-995

10.1093/gerona/glx172 | PMID 29788088

Report: NIA Workshop on Measures of Physiologic Resiliencies in Human Aging

The Journals of Gerontology: Series A | May 5, 2017 | Volume: 72 | Issue: 7 | Pages: 980-990

10.1093/gerona/glx015 | PMID 28475732

Disease drivers of aging

Annals of the New York Academy of Sciences | December 14, 2016 | Volume: 1386 | Issue: 1 | Pages: 45-68

10.1111/nyas.13299 | PMID 27943360

It has long been known that aging, at both the cellular and organismal levels, contributes to the development and progression of the pathology of many chronic diseases. However, much less research has examined the inverse relationship—the contribution of chronic diseases and their treatments to the progression of aging‐related phenotypes. Here, we discuss the impact of three chronic diseases (cancer, HIV/AIDS, and diabetes) and their treatments on aging, putative mechanisms by which these effects are mediated, and the open questions and future research directions required to understand the relationships between these diseases and aging.