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Petersen, Ronald

https://orcid.org/0009-0006-8296-6416

A5110342810 | I1330342723

Mayo Clinic

Mayo Clinic

Citations 70

F5‐05‐03: Detecting Functional Impairment in Preclinical Alzheimer’s Disease using a Brief Performance Measure of Financial Skills

Alzheimer's & Dementia | October 17, 2016 | Volume: 12 | Issue: 7S_Part_7 | Pages: No page available

10.1016/j.jalz.2016.06.701

Association Between Anticholinergic Medication Use and Cognition, Brain Metabolism, and Brain Atrophy in Cognitively Normal Older Adults

JAMA Neurology | April 18, 2016 | Volume: 73 | Issue: 6 | Pages: 721

10.1001/jamaneurol.2016.0580 | PMID 27088965

IC‐P‐034: Anticholinergic medication use in older adults is associated with memory and hippocampal volume

Alzheimer's & Dementia | December 15, 2015 | Volume: 11 | Issue: 7S_Part_1 | Pages: No page available

10.1016/j.jalz.2015.06.054

P3‐014: Influence of rare RELN variants on quantitative PET imaging and CSF phenotypes in late‐onset Alzheimer's disease

Alzheimer's & Dementia | December 15, 2015 | Volume: 11 | Issue: 7S_Part_13 | Pages: No page available

10.1016/j.jalz.2015.06.880

P1‐193: Anticholinergic medication use in older adults is associated with memory and hippocampal volume

Alzheimer's & Dementia | December 15, 2015 | Volume: 11 | Issue: 7S_Part_9 | Pages: No page available

10.1016/j.jalz.2015.06.392

IC‐P‐042: Influence of rare reelin variants on quantitative PET imaging and CSF phenotypes in late‐onset Alzheimer's disease

Alzheimer's & Dementia | December 15, 2015 | Volume: 11 | Issue: 7S_Part_1 | Pages: No page available

10.1016/j.jalz.2015.06.062

P1‐319: Alzheimer's prevention registry: A shared resource to the scientific community to facilitate enrollment in studies

Alzheimer's & Dementia | December 15, 2015 | Volume: 11 | Issue: 7S_Part_10 | Pages: No page available

10.1016/j.jalz.2015.06.534

P2‐079: Neuronal origin plasma exosomes provide novel biomarkers for lysosomal dysfunction in Alzheimer's disease

Alzheimer's & Dementia | December 15, 2015 | Volume: 11 | Issue: 7S_Part_11 | Pages: No page available

10.1016/j.jalz.2015.06.616

Brain amyloidosis ascertainment from cognitive, imaging, and peripheral blood protein measures

Neurology | January 22, 2015 | Volume: 84 | Issue: 7 | Pages: 729-737

10.1212/wnl.0000000000001231 | PMID 25609767

Protective variant for hippocampal atrophy identified by whole exome sequencing

Annals of Neurology | January 5, 2015 | Volume: 77 | Issue: 3 | Pages: 547-552

10.1002/ana.24349 | PMID 25559091

We used whole‐exome sequencing to identify variants other than APOE associated with the rate of hippocampal atrophy in amnestic mild cognitive impairment. An in‐silico predicted missense variant in REST (rs3796529) was found exclusively in subjects with slow hippocampal volume loss and validated using unbiased whole‐brain analysis and meta‐analysis across 5 independent cohorts. REST is a master regulator of neurogenesis and neuronal differentiation that has not been previously implicated in Alzheimer's disease. These findings nominate REST and its functional pathways as protective and illustrate the potential of combining next‐generation sequencing with neuroimaging to discover novel disease mechanisms and potential therapeutic targets. Ann Neurol 2015;77:547–552