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Juan, Jiaxiang

0009-0009-5170-9152

A5044143958 | I3923682

Mayo Clinic

Soochow University

Citations 1

The ubiquitin ligase HERC4 mediates c-Maf ubiquitination and delays the growth of multiple myeloma xenografts in nude mice

Blood | January 30, 2016 | Volume: 127 | Issue: 13 | Pages: 1676-1686

10.1182/blood-2015-07-658203 | PMID 26825710

Key Points HERC4 is the first identified ubiquitin ligase that mediates c-Maf ubiquitination and degradation. HERC4 suppresses MM cell proliferation and delays MM tumor growth.