Back to Authors

Patterson, Kara

A5057985193 | I52357470

Mayo Clinic

The Ohio State University

Citations 1

Validation of ZAP-70 methylation and its relative significance in predicting outcome in chronic lymphocytic leukemia

Blood | May 28, 2014 | Volume: 124 | Issue: 1 | Pages: 42-48

10.1182/blood-2014-02-555722 | PMID 24868078

Key Points Methylation analysis at ZAP-70 CpG+223 in CLL provides superior prognostic information vs IGHV status or CD38 or ZAP-70 expression. A pyrosequencing method for the feasible assessment of CpG+223 methylation in CLL samples is provided.