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C.H., Alvin

A5112312320 | I4210125099

Mayo Clinic

Mayo Clinic in Arizona

Citations 1

Functions of flt3 in zebrafish hematopoiesis and its relevance to human acute myeloid leukemia

Blood | March 4, 2014 | Volume: 123 | Issue: 16 | Pages: 2518-2529

10.1182/blood-2013-02-486688 | PMID 24591202

Key Points Zebrafish flt3 plays an important role in the initiation of definitive hematopoietic stem cells. Expression of human FLT3-ITD activates endogenous flt3 signaling and induces myeloid expansion.