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Wolf, Matthew J.

Mayo Clinic

Mayo Clinic

Citations 1

Comparison of the BioFire Joint Infection Panel to 16S Ribosomal RNA Gene-Based Targeted Metagenomic Sequencing for Testing Synovial Fluid from Patients with Knee Arthroplasty Failure

Journal of Clinical Microbiology | November 21, 2022 | Volume: 60 | Issue: 12 | Pages: No page available

10.1128/jcm.01126-22 | PMID 36409108

The diagnosis of periprosthetic joint infection (PJI) is challenging, often requiring multiple clinical specimens and diagnostic techniques, some with prolonged result turnaround times. Here, the diagnostic performance of the Investigational Use Only (IUO) BioFire Joint Infection (JI) Panel was compared to 16S rRNA gene-based targeted metagenomic sequencing (tMGS) applied to synovial fluid for PJI diagnosis.