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Li, Yong

Mayo Clinic

Children's Hospital of Philadelphia

Citations 1

Optimized depletion of chimeric antigen receptor T cells in murine xenograft models of human acute myeloid leukemia

Blood | February 28, 2017 | Volume: 129 | Issue: 17 | Pages: 2395-2407

10.1182/blood-2016-08-736041 | PMID 28246194

Key Points Depletion of CD123-redirected CAR T cells with monoclonal antibodies preserves leukemia remission in human AML xenograft models. AML CAR T-cell depletion enhances feasibility of subsequent allogeneic stem cell transplantation.